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The incidence of atherosclerosis is significantly increased in rheumatoid arthritis (RA). Infection is one factor that may be involved in the pathogenesis of both diseases. The cause of RA and atherosclerosis is unknown, and infection is one of the factors that may be involved in the pathogenesis of both diseases. The aims of this study were to identify bacteria in the aortic adventitia of patient
The inducement of electroactive consortia was carried Out in dual-chamber MFCS using acetate-based substrate- and a protein-rich synthetic wastewater in fed-batch mode. The characteristics of these MFCs were then compared. MFCs based on acetate-induced consortia (MFCAce) achieved more than twice higher maximum power, and one half of optimal external resistance in comparison to MFCs based on consor
The goal of the present study was to elucidate what influences medical students' attitudes and interests in medical ethics. At the end of their first, fifth and last terms, 409 medical students from all six medical schools in Sweden participated in an attitude survey. The questions focused on the students' experience of good and poor role models, attitudes towards medical ethics in general and per
Biosensors based on whole bacterial cells and on bacterial heavy metal binding protein were used to determine the mercury concentration in soil. The soil samples were collected in a vegetable garden accidentally contaminated with elemental mercury 25 years earlier. Bioavailable mercury was measured using different sensors: a protein-based biosensor, a whole bacterial cell based biosensor, and a pl
Popular Abstract in Swedish Medan akut smärta ofta kan bemästras på ett framgångsrikt sätt saknas ofta adekvat behandling av kroniska smärttillstånd. Smärta är ett dominerande symptom vid en mängd sjukdomar såsom till exempel, reumatoid artrit, cancer, migrän, ryggskador, fibromyalgi och tillgängliga analgetika är ofta otillräckliga. Det finns därför ett stort behov att utveckla nya och effektiva Introduction: To understand the function of the genes and their products in the pain system, studies will have to deal with complex issues related to intercellular communication, e.g. plasticity in neuronal networks. To provide a basis for such studies, the present thesis compares basic features of the nociceptive spinal systems including the organization of nociceptive withdrawal reflexes (NWR),
Since the 1950's, mass tourism has become a considerable part of modern western culture. Examining where, why and how people have traveled can tell us a lot about people's habits and cultural frames of reference. Yet, the area of tourism history is fairly uncharted, with travelogs being one of the more prevalent objects of interest for academic research. Research focused on travel guides a
Abstract: Before the introduction of prostate MRI, prostate cancer screening relied on prostate-specific antigen (PSA) testing followed by a systematic biopsy. Although this approach reduced prostate cancer mortality in large, randomized screening trials, its net benefit was questionable because of substantial overdiagnosis. In response, more precise screening tools have been developed. Diagnostic
Climate change models predict an increase in the intensity and frequency of drought periods as well as precipitation events. Moisture and its fluctuations have a large impact on soil microorganisms, which are key drivers of the terrestrial carbon (C) cycle. When there is a drought period followed by a rainfall event there is a big CO2 release from soil to the atmosphere, which can dominate the C b
Den här avhandlingen har som syfte att bidra till att täcka kunskapsluckor om hur tilläggssvårigheter vid attention deficit hyperactivity disorder (ADHD) hos barn förändras och om dessa har ett samband med hur ADHD-problematiken utvecklas under 3 års tid. ADHD är en utvecklingsrelaterad kognitiv funktionsnedsättning som debuterar hos barn och unga, 12 år eller yngre, genom höga nivåer av ouppmärksClarification on how cognitive, executive and emotional functioning contribute to symptom reduction or improved function in childhood attention deficit hyperactivity disorder (ADHD) is needed to find additional treatment methods. The clinical utility of continuous performance test (CPT) (Conners’ CPT-II, QbTest) to complement rating scales in diagnostic assessments and treatment evaluations (QbTes
Background: Anorectal malformations (ARM) occur in 1/5000 live births (1.2–1.6:1 male:female). Associated malformations are common, influencing, together with ARM-subtype complexity, long-term outcome, follow-up and need of transitional care. Reconstructive surgery, the posterior sagittal anorectoplasty (PSARP), is performed in infancy, either as a single-stage or multi-stage procedure with a colo
Identification of prostate gold fiducial markers in magnetic resonance imaging (MRI) images is challenging when CT images are not available, due to misclassifications from intra-prostatic calcifications. It is also a time consuming task and automated identification methods have been suggested as an improvement for both objectives. Multi-echo gradient echo (MEGRE) images have been utilized for manu
This cross-country comparison of administrative responses to the COVID-19 pandemic in France, Germany and Sweden is aimed at exploring how institutional contexts and administrative cultures have shaped strategies of problem-solving and governance modes during the pandemic, and to what extent the crisis has been used for opportunity management. The article shows that in France, the central governme
Editorial: This focus is dedicated to a special trend on the scenes of contemporary music: composers going on stage to perform their own pieces.The presented articles were developed during my research project 'The Creator on Stage'. They can be read as selection of perspectives, commentaries, analyses, reflections and gained knowledge-production on the topic.The intention with the project was part
This research aims to develop efficient process technologies that are capable of converting/utilising CO2 streams into energy-rich liquid products (fuels). This would result in better solutions with near-zero-carbon-emissions level. From an energetic and economic point of view, methanol synthesis from CO2 is a competitive alternate to methanol production from biomass. Our work considers the CO2 ba
Today, between 8% and 16% of all individuals worldwide suffer from chronic kidney disease (CKD), which is becoming a growing public health issue. Creatinine and cystatin C are commonly used markers for kidney function, and estimated glomerular filtration rate (eGFR) and albuminuria are used to stage CKD. However, creatinine and eGFR are rather insensitive in identifying individuals at high risk of
During the #metoo movement in the autumn of 2017, stories about sexual assault, including rape, garnered much attention worldwide. It might seem as if all of these stories came from nowhere. In fact, during the last decades several rape cases have been highlighted and debated in media all over the world. These discussions in the media and among the general public have led to scrutiny and a critica
A large number of systemically administered drugs have the potential to cause drug-induced interstitial lung disease (DIILD). We aim to characterize a model of DIILD in the rat and develop imaging biomarkers (IBs) for detection and quantification of DIILD. In this study, Sprague–Dawley rats received one single dose of intratracheal (i.t.) bleomycin and were longitudinally imaged at day 0, 3, 7, 14
Context While vascular endothelial growth factor-targeted therapy and mammalian target of rapamycin inhibition are effective strategies in treating clear cell renal cell carcinoma (ccRCC), the most effective therapeutic approach for patients with non-clear cell RCC (non-ccRCC) is unknown. Objective To systematically review relevant literature comparing the oncological outcomes and adverse events o
