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The aim of this study was to explore how healthcare counselors in their role as child representatives at adult habilitation clinics in Sweden experience the implementation of support for children as next of kin. Healthcare law in Sweden states that children as next of kin are entitled to information, advice and support by healthcare professionals when living together with an adult relative that ha
In recent years, several men in Sweden have been acquitted of different sexual offences because the courts deemed that it could have occurred in their sleep. According to a leading expert, several of the Swedish acquitting cases are based on incorrect or irrelevant arguments and reasoning regarding sexsomnia. Therefore, it is important to gain a deeper understanding of how sexsomnia manifests with
Lagstiftaren har gjort bedömningen att barn i åldrarna 15-17 år bör skyddas från vissa sexuella handlingar och därför har man kriminaliserat köp av sexuell handling av barn. För att ansvar ska kunna utkrävas måste gärningspersonen ha uppsåt ifråga om alla omständigheter utom barnets ålder, där måste denne endast agerat oaktsamt. Enligt 6:13 BrB kan en person dömas för köp av sexuell handling av ba
Introduction: In former studies from North America early Do-Not-Resuscitate orders (DNR orders) in patients with intracerebral haemorrhage (ICH) had negative prognostic impact on mortality. The influence of DNR orders on functional outcome and whether DNR orders are grounded on relevant patient characteristics is unknown. We aimed to determine the frequency and predictive factors of DNR-orders and
Background: Risk gene variants for celiac disease, identified in genome-wide linkage and association studies, might influence molecular pathways important for disease development. The aim was to examine expression levels of potential risk genes close to these variants in the small intestine and peripheral blood and also to test if the non-coding variants affect nearby gene expression levels in chi
Based on a literature review and the SSG experience, the most important prognostic factors in high-grade osteosarcoma appear to be the presence of detectable metastases at diagnosis, tumour volume, old age, sex, histologic response, and possibly tumoral P-glycoprotein expression. However, for an adolescent patient with non-metastatic extremity disease, there is no consensus regarding prognostic fa
Background Ligands of peroxisome proliferator-activated receptor alpha (PPAR-alpha) have been shown to reduce ischaemia/reperfusion injury. The mechanisms behind this effect are not well known. We hypothesized that activation of PPAR-alpha exerts cardioprotection via a mechanism related to nitric oxide (NO) and endothelin-1 (ET-1). Methods Five groups of anaesthetized open-chest Sprague-Dawley rat
Background: Contamination of drinking water by hazardous chemicals can be associated with human health risks. Recent studies using effect-based in vitro methods have demonstrated that a large part of the observed toxic effects are caused by unknown chemicals. In this study, we have used a panel of effect-based methods to study the presence of chemical contaminants in a unique material; glass-bottl
Objectives: Thermal and mechanical stresses during osteotomy preparation can impair implant osseointegration. This study investigated implant osseointegration following the measurement of temperature exposure during osteotomy drilling, varying drill design, sequence, and drill wear. Materials and methods: 36 tapered implants were placed in a mandibular minipig model after guided drilling of implan
Background: Treatment adaptation based on tumour biomarker response during radiotherapy of prostate cancer, could be used for both escalation and de-escalation of radiation doses and volumes. To execute an adaptation involving extension of treatment volumes during radiation can however be restricted by the doses already delivered. The aim of this work was to develop a treatment planning method tha
BACKGROUND: Gastrointestinal complications in diabetes may affect glucose and endocrine homeostasis. Glucosedependent insulinotropic peptide (GIP), glucagon-like peptide-1 (GLP-1), and leptin regulate glucose homeostasis, food intake, and gastric emptying. AIM: The aim was to investigate associations between diabetes complications and glucose homeostasis and plasma levels of GIP, GLP-1, and leptin
For some time, directional antennas have been considered to solve connectivity and interference issues in wireless networks. Several scenarios have been presented and often the conclusions drawn are positive, showing increase in capacity. However, to date there has been no effort to assess a holistic picture of the benefit/cost tradeoff and previous work mainly concerns either link scheduling or a
During pregnancy and involution, an extensive remodelling of the human cervical connective tissue occurs. This cervical ripening is one of the most pronounced physiological remodelling processes known in human connective tissue. To investigate how the remodelling is accomplished, the levels of mRNA for collagen I and III, versican and three small proteoglycans, biglycan, decorin and fibromodulin,
Lipases are the main fat digestive enzymes present in the digestive system of many animals, microorganisms and plants. Probiotic microorganisms that can possibly produce enzymes are of crucial importance since it can have an effect on human health. Two of the main probiotic strains are Lactobacillus rhamnosus and Biffidobacterium longum, in each there was a putative lipase encoded on the DNA and t
Kristianstadsslätten breder ut sig i nordöstra Skåne och in i sydvästra Blekinge med sin komplicerade och varierade geologi. De komplexa förhållandena leder till att det finns ett flertal akvifärer i både jordlager och berggrund, där den mest vattenförande formationen är den av glaukonitsand. Syftet med arbetet har varit att undersöka vilket infiltrerat vattenflöde, vid vilket pumptryck, en brunn Kristianstad plain stretches from the northeast of Scania to the southwest of Blekinge with a complicated and varying geology. The complexity has resulted in multiple aquifers in both soil and bedrock, where the highest amount of withdrawable groundwater is in the formation of glauconite sand. The aim of this paper has been to investigate which infiltrated water flow at a certain pumping pressure,
Chemical hazard assessment is a procedure in chemical regulation to set which concentrations of chemical substances that are safe to an ecological system, i.e. where a majority of the species in the systems is not negatively affected by the substance. The Species Sensitivity Distribution (SSD) is an assessment model to estimate hazardous concentration based on toxicity data from representative spe
