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Chemical hazard assessment is a procedure in chemical regulation to set which concentrations of chemical substances that are safe to an ecological system, i.e. where a majority of the species in the systems is not negatively affected by the substance. The Species Sensitivity Distribution (SSD) is an assessment model to estimate hazardous concentration based on toxicity data from representative spe
A model is used to describe a system physically or mathematically and to give information about changes in the system variables. Physical knowledge about the system and its quantities can be useful to build a physical model obeying the laws of nature. However, if the system is to be regarded as a black box with only input and output signals, system identification can be used to fit a mathematical
Sustainable finance has become of great importance over the past years, especially due to global climate development, resulting in increased awareness among public and private sectors, and hence, more conscientious investors. In a market familiar with green bonds, Sustainability-Linked Bonds (SLBs) emerged as a new financial instrument posing a lesser greenwashing risk and, therefore, greater pote
The Greenhouse Gas Reduction Mandate (GGRM, reduktionsplikten) is Swedish legislation focused on reducing carbon emissions by mandating that the emissions of certain fuels are reduced by a specified percentage, that percentage increasing each year. This paper investigates the rationale behind a political drive to decrease the GGRM, the cost-effectiveness of the GGRM, and the consequences of t
With significant changes expected in the earth's global climate over the next century, due to global warming, and its resulting changes in the frequency and amount of precipitation, there has been growing concerns on climate change impacts on water resources. Especially concerned to water managers and governments is the potential impacts on groundwater aquifers since they are the main availabl
The formation of industry standards for environmental issues and corporate social responsibility is gaining acceptance but the number of successfully implemented programs are few. On an individual level companies have for some time applied company standards or codes of conduct. But on a collective level cooperation seems much more difficult. Although from an economic point of view there are clear
Populärvetenskaplig sammanfattning: Småvatten är en svacka eller hålighet som är vattenfylld året om. Dessa småvatten fyller många viktiga funktioner i naturen. De fungerar som utjämnare av flödesvariationer, uppehållsplats och födoplats för många djur och växter och som rena estetiska inslag i naturen, och inte minst som reningsplatser för oönskade näringsämnen så som kväve. Dessa småvatten har iWetlands play an important role in the ecosystem. They reduce the impact of flow flux in the drainage area, acts as upholder of biodiversity, as an esthetic and recreational component in the landscape and they have the ability to reduce nutrients such as nitrogen, and help preventing eutrophication in costal areas. The number of wetlands in Scania have, due to the intensified agriculture been redu
Towards a New Eldercare? Middle managers reflections on how to create good service within homes for the elderly. [translated title] For the past twenty years there has been a governing trend of efficiency and privatization of the swedish elder care. These trends have put the elder cares very foundation, it’s purpose, in a tremble. Middle managers within the swedish elder care are struggling to
En ökad medvetenhet om värdet av ett rent grundvatten yttrar sig i allt fler sammanhang, bl.a. i det nationella miljömål om grundvatten av god kvalitet som riksdagen presenterat. Simrishamns kommun ser över vattenskyddsområdena runt kommunens grundvattentäkter för att säkerställa ett rent grundvatten. Målet med detta examensarbete är att ta fram ett underlag som skall kunna ligga till grund för avThe increased awareness of the value of clean groundwater can be seen in a growing number of contexts. This is also emphasized in the national environmental goals, put up by the Swedish government. The municipality of Simrishamn, in southern Sweden, is re-evaluating the extension of the existing restriction areas around the groundwater wells of the municipality. The aims in this investigation were
Background: Giant cell arteritis (GCA; sometimes referred to as temporal arteritis) and polymyalgia rheumatica (PMR) are common and interrelated inflammatory conditions that almost exclusively affect adults older than 50 years. There is a need for updated information on the epidemiology of these diseases. Objective: This systematic literature review (SLR) aims to summarize current evidence regardi
Background: During 2013 and 2016 the region of Skåne, Sweden started to analyse human papillomavirus (HPV) and cytology in postmenopausal women 60–65 years of age. Our aim was to evaluate high-risk (HR) HPV mRNA testing for the triage of HPV DNA-positive postmenopausal women with normal cytology. Methods: A total of 271 women, 60–65 years of age, underwent liquid-based cytology (LBC) and HPV testi
BACKGROUND: Highly increased risk of injuries has been noted around the time of cancer diagnosis. Whether there is a similar increase in risk around the diagnosis of cervical cancer and its precursor lesions was unknown.METHODS: We performed a cohort study including 3,016,307 Swedish women that participated in cervical screening during 2001 to 2012. We calculated the incidence rates (IR) of hospit
OBJECTIVES: Stroke is a serious complication in patients with acute type A aortic dissection (ATAAD). Previous studies investigating stroke in ATAAD patients have been limited by small cohorts and have shown diverging results. We sought to identify risk factors for stroke and to evaluate the effect of stroke on outcomes in surgical ATAAD patients. METHODS: The Nordic Consortium for Acute Type A Ao
INTRODUCTION: The pituitary gland has a high expression of somatostatin receptors (SSTRs) and is therefore a potential organ at risk for radiation-induced toxicity after 177Lu-DOTATATE treatment.OBJECTIVE: To study changes in pituitary function in patients with neuroendocrine tumors (NETs) treated with dosimetry-based 177Lu-DOTATATE to detect possible late toxicity.METHODS: 68 patients from a phas
Statistical emulation allows combining advantageous features of statistical and process-based crop models for understanding the effects of future climate changes on crop yields. We describe here the development of emulators for nine process-based crop models and five crops using output from the Global Gridded Model Intercomparison Project (GGCMI) Phase 2. The GGCMI Phase 2 experiment is designed w
Aim: To examine the hypothesis that, based on their glucose curves during a seven-point oral glucose tolerance test, people at elevated type 2 diabetes risk can be divided into subgroups with different clinical profiles at baseline and different degrees of subsequent glycaemic deterioration. Methods: We included 2126 participants at elevated type 2 diabetes risk from the Diabetes Research on Patie
Background: Ultra-high field magnetic resonance imaging (MR) may be used to improve intracranial blood flow measurements. However, standard cardiac synchronization methods tend to fail at ultra-high field MR. Therefore, this study aims to investigate an alternative synchronization technique using Doppler ultrasound. Methods: Healthy subjects (n = 9) were examined with 7T MR. Flow was measured in t
Context.-The diagnostic distinction of pulmonary neuroendocrine (NE) tumors from non-small cell lung carcinomas (NSCLCs) is clinically relevant for prognostication and treatment. Diagnosis is based on morphology and immunohistochemical staining. Objective.-To determine the diagnostic value of insulinoma-associated protein 1 (INSM1), in comparison with established NE markers, in pulmonary tumors. D
