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Despite improvements, lung transplantation remains hampered by both a scarcity of donor organs and by mortality following primary graft dysfunction (PGD). Since acute respiratory distress syndrome (ARDS) limits donor lungs utilization, we investigated cytokine adsorption as a means of treating ARDS donor lungs. We induced mild to moderate ARDS using lipopolysaccharide in 16 donor pigs. Lungs were

BACKGROUND: Asthma is the most frequent chronic disease in children. One of the most replicated genetic findings in childhood asthma is the ORMDL3 gene confirmed in several GWA studies in several paediatric populations.OBJECTIVES: The purpose of this study was to analyse ORMDL3 variants and expression in childhood asthma in the Polish population.MATERIALS AND METHODS: In the study we included 416

Multiple sclerosis leads to diffuse damage of the central nervous system, affecting also the normal-appearing white matter. Demyelination and axonal degeneration reduce regional fractional anisotropy in normal-appearing white matter, which can be routinely mapped with diffusion tensor imaging. However, the standard fractional anisotropy metric is also sensitive to physiological variations in orien

Hematopoietic stem cells (HSCs) enable hematopoietic stem cell transplantation (HCT) through their ability to replenish the entire blood system. Proliferation of HSCs is linked to decreased reconstitution potential, and a precise regulation of actively dividing HSCs is thus essential to ensure long-term functionality. This regulation becomes important in the transplantation setting where HSCs unde

IMPORTANCE Moderate-grade adolescent idiopathic scoliosis (AIS) may be treated with full-time bracing. For patients who reject full-time bracing, the effects of alternative, conservative interventions are unknown. OBJECTIVE To determine whether self-mediated physical activity combined with either nighttime bracing (NB) or scoliosis-specific exercise (SSE) is superior to a control of physical activ

The X-linked DDX3X gene encodes an ATP-dependent DEAD-box RNA helicase frequently altered in various human cancers, including melanomas. Despite its important roles in translation and splicing, how DDX3X dysfunction specifically rewires gene expression in melanoma remains completely unknown. Here, we uncover a DDX3X-driven post-transcriptional program that dictates melanoma phenotype and poor dise

Abstract Noroviruses are now the leading cause of gastroenteritis worldwide. Noroviruses are effectively transmitted due to a low infectious dose, viral shedding in high concentrations, environmental stability, and they induce only a limited immunity after infection. Especially, the norovirus variants of genotype II.4 (GII.4) have seemed greatly adapted for pandemic spread. The high infectivity of

BACKGROUND: Osteoarthritis is a leading cause of disability worldwide. Current treatment supports coping strategies to improve health-related quality of life (HRQoL). The need to predict response to treatment has been raised to personalise care. This study aims to examine change in HRQoL from baseline to three and nine months follow-up after participating in a Supported Osteoarthritis Self-Managem

Background and Objectives: There is considerable heterogeneity in the association between increasing β-amyloid (Aβ) pathology and early cognitive dysfunction in preclinical Alzheimer disease (AD). At this stage, some individuals show no signs of cognitive dysfunction, while others show clear signs of decline. The factors explaining this heterogeneity are particularly important for understanding pr

Background: The failing heart is traditionally described as metabolically inflexible and oxygen starved, causing energetic deficit and contractile dysfunction. Current metabolic modulator therapies aim to increase glucose oxidation to increase oxygen efficiency of adenosine triphosphate production, with mixed results. Methods: To investigate metabolic flexibility and oxygen delivery in the failing

Background: Gallbladder cancer (GBC) is rare but aggressive. The extent of surgical intervention for different GBC stages is non-uniform, ranging from cholecystectomy alone to extended resections including major hepatectomy, resection of adjacent organs and routine extrahepatic bile duct resection (EBDR). Robust evidence here is lacking, however, and survival benefit poorly defined. This study ass

Objective: Analyze the outcomes of endovascular complex abdominal and thoracoabdominal aortic aneurysm repair using the Cook fenestrated device with the modified preloaded delivery system (MPDS) with a biport handle and preloaded catheters. Methods: A multicenter retrospective single arm cohort study was performed, including all consecutive patients with complex abdominal aortic aneurysm repair an

This article presents a fully integrated millimeter-wave (mmW) transceiver front end covering 24.25–29.5 GHz. It features a wideband Doherty power amplifier utilizing adaptive bias and a transmit/receive switch (TRX-switch) that has embedded low noise amplifier to antenna matching. The phase shift of 90 $^\circ$ to

BACKGROUND: Patients with diabetes have increased rates of major adverse cardiac events (MACEs). We hypothesized that this is explained by diabetes-associated differences in coronary plaque morphology and lipid content. METHODS: In PROSPECT II (Providing Regional Observations to Study Predictors of Events in the Coronary Tree), 898 patients with acute myocardial infarction with or without ST-segme

We present a novel method for the determination of density and compressibility of individual particles and cells undergoing microchannel acoustophoresis in an arbitrary 2D acoustic field. Our method is a critical advancement within acoustophoretic separation of biological cells, as the ability to determine the density and compressibility of individual cells enables the prediction and alteration of

This paper presents an improved synthetic loading method to measure the performance of an interior permanent magnet synchronous machine (IPMSM). A complete analysis of torque-, flux-, and efficiency-maps are done by means of a vector controlled drive implemented with in a field programmable gate array (FPGA). The measurements are compared to results from Finite Element Analysis (FEA). A key featur

BACKGROUND CONTEXT: Several studies report a favorable short-term outcome after nonoperatively treated two-column thoracic or lumbar burst fractures in patients without neurological deficits. Few reports have described the long-term clinical and radiological outcome after these fractures, and none have, to our knowledge, specifically evaluated the long-term outcome of the discs adjacent to the fra

2 3 Skånska är mitt modersmål UtställningsprodUktion: Håkan Håkansson, Mikael lindgren, Birgitta lindHolM, Jan-eric MalMqUist, svante nordin Foto: Bengt Melliander Utställningsansvarig: BJörn dal en Utställning oM Frans g. Bengtsson Universitetsbibliotekets utställningskatalog 59 Universitetsbiblioteket, Lunds universitet Box 3, 221 00 LUND UB Media. ISSN 0281-3823 LULID/LIBR - 1547 rans G. Bengts

https://www.ub.lu.se/en/sites/ub.lu.se.en/files/2010_frans_g_bengtsson.pdf - 2026-05-24

- - Lunds universitets målsättning inom arbetsmiljöarbetet Lunds universitet har som målsättning att, genom ett systematiskt arbetsmiljöarbete (SAM), erbjuda anställda och studerande en god arbetsmiljö. Årlig uppföljning av det systematiska arbetsmiljöarbetet, SAM Syftet med denna uppföljning är att universitetets högsta ledning får klart för sig hur arbetsmiljöarbetet har fungerat samt om och på

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2018_sam-uppfoljning_lu-mall.pdf - 2026-05-24

PPoolliiccyy aanndd IInnssttiittuuttiioonnaall AAssppeeccttss ooff WWaatteerr RReessoouurrcceess MMaannaaggeemmeenntt iinn NNiiccaarraagguuaa -- TThhee ccaassee ooff MMaannaagguuaa MMaasstteerr''ss TThheessiiss By Marisa Espinosa December 2000 AAddddrreessss:: 6492 rue Pérodeau Montréal, Canada, H1M 1J4 Email: isaespinosa@bigfoot.com SSuuppeerrvviissoorr:: Peder Hjorth Department of Water Resource

https://www.lumes.lu.se/sites/lumes.lu.se/files/espinosa_marisa.pdf - 2026-05-24