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Association Between Preoperative Opioid and Benzodiazepine Prescription Patterns and Mortality After Noncardiac Surgery

IMPORTANCE: The number of patients prescribed long-term opioids and benzodiazepines and complications from their long-term use have increased. Information regarding the perioperative outcomes of patients prescribed these medications before surgery is limited.OBJECTIVE: To determine whether patients prescribed opioids and/or benzodiazepines within 6 months preoperatively would have greater short- a

Working in the 'White man's grave': Wages and Migration from Europe to the Gold Coast in the Eighteenth Century

This article examines the economic incentives for Europeans to migrate to the so-called 'white man's grave' of West Africa. Ignorance and coercion have been proposed as explanations for migration to high mortality areas. We use data on the Royal African Company and their European employees on the Gold Coast during the period 1707-1740. We found that the employees received a premium above the wage

Antisecretory factor in severe traumatic brain injury (AFISTBI) : protocol for an exploratory randomized placebo-controlled trial

Background: Despite recent advances in neuroimaging and neurocritical care, severe traumatic brain injury (TBI) is still a major cause of severe disability and mortality, with increasing incidence worldwide. Antisecretory factor (AF), commercially available as Salovum®, has been shown to lower intracranial pressure (ICP) in experimental models of, e.g., TBI and herpes encephalitis. The aim of this

Adverse Pregnancy Outcomes and Long-Term Risk of Heart Failure in Women : National Cohort and Co-Sibling Study

Background: Adverse pregnancy outcomes, such as preterm delivery and hypertensive disorders of pregnancy, may be associated with higher future risks of heart failure (HF). However, the comparative effects of different adverse pregnancy outcomes on long-term risk of HF, and their potential causality, are unclear. OBJECTIVES: The authors sought to examine 5 major adverse pregnancy outcomes in relati

Association between movement synchrony and psychological pain in therapies with suicide attempters

Introduction: Psychological pain is a central risk factor for suicidal behaviour. Nonverbal synchrony between patients and therapists has been shown to facilitate the development of therapeutic alliance, which in turn is linked to symptom reduction. Building on these associations, the present study investigated whether movement synchrony in suicide-specific therapy exceeds random synchrony and whe

När brottsoffer blir gärningsperson – En genusrättsvetenskaplig analys av det svenska förtalsbrottet i kölvattnet av #metoo

Sedan #metoo-hösten 2017 har ett trettiotal kvinnor som berättat om sexuella övergrepp på sociala medier dömts för förtal i Sverige. Den svenska förtalslagstiftningen, som skiljer sig från andra länders reglering på området, har därför kritiserats. I Sverige existerar det inte någon allmän rätt att få säga sanningen. I detta arbete undersöks den svenska förtalslagstiftningen utifrån ett genusrätSince the #metoo movement which started in the autumn of 2017, around thirty women who has spoken out about sexual assault on social media has been convicted of defamation in Sweden. Therefore, the Swedish defamation law has been criticized, which differs from other countries´ regulations in the area. In Sweden, there is no general right to tell the truth. This essay examines the Swedish defamat

Pulmonary Nodule Prevalence at CT in Middle-Aged Participants from the Swedish CArdioPulmonary bioImage Study (SCAPIS)

Background Pulmonary nodules (PNs) are clinically challenging because differentiation between benign and malignant PNs is not possible at CT detection; recurring CT examinations and invasive procedures are often required in PN follow-up. Purpose To investigate PN prevalence in a middle-aged population and the risk factors associated with these nodules. Materials and Methods In this secondary analy

Unlocking Creativity: Integrating Electronic Digital Instruments in Music Education

The EDI Guidelines (https://www.ediguidelines.se), an outcome of the Swedishgovernment funded practice-based school research project “The Digital Student -Challenges and Opportunities with the Computer as an Instrument in Music Education” (2021-2024), provide a valuable resource for integrating Electronic Digital Instruments (EDI) into music education in upper secondary school. This workshop is de

Plasma pTau 217/β-amyloid 1–42 ratio for enhanced accuracy and reduced uncertainty in detecting amyloid pathology

Blood biomarkers have the potential to revolutionize Alzheimer's disease diagnosis, offering advantages over CSF and PET due to their accessibility, scalability and cost-effectiveness. This study evaluated the effectiveness of individual plasma biomarkers, such as phosphorylated Tau (pTau) 217, as well as biomarker combinations, with a focus on the pTau 217/β-Amyloid (Aβ) 1–42 ratio to predict amy

Building study-related relationships : How student relationships and readiness affect academic outcome in higher education

The present dissertation explores students’ perception of their own readiness for higher education and students’ study related relations and the effect on academic outcome. The complexity of student engagement and academic success means that it is relevant to conduct in-depth studies of particular student populations, to explore how certain factors play out in that specific context. First, student

Transcriptional Responses as Biomarkers of General Toxicity : A Systematic Review and Meta-Analysis on Metal-Exposed Bivalves

Through a systematic review and a series of meta-analyses, we evaluated the general responsiveness of putative transcriptional biomarkers of general toxicity and chemical stress. We targeted metal exposures performed on bivalves under controlled laboratory conditions, and selected six transcripts associated with general toxicity for evaluation: catalase (cat), glutathione-S-transferase (gst), heat