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Comparison of the C-REX LapAid and Circular Stapled Colorectal Anastomoses in an Experimental Model

The rate of colorectal anastomotic leakage has remained unchanged for the last decades. The limitations of current anastomotic methods have generated an interest in alternative anastomotic techniques, such as compression anastomosis. The aim of this experimental study was to evaluate the early mechanical strength in left colonic anastomoses, comparing C-REX LapAid and circular stapled anastom

Tetrabromobenzene-based molecular alloys - a tool for tailoring the temperature of the thermosalient phase transition

A series of molecular alloys of 1,2,4,5-tetrabromobenzene and 1,2,4,5-tetrachlorobenzene with varying compositions were prepared in an attempt to obtain jumping crystals with adjustable temperature of thermosalient phase transition. Molecular alloys were studied with a combination of thermal and structural techniques (DSC, SCXRD, XRPD, hot-stage microscopy). Alloys with a high 1,2,4,5-tetrabromobe

The Burden to Plead Legal Facts

En vetenskaplig text i vilken jag på engelska och för en internationell läsarkrets presenterar de centrala forskningsresultaten och slutsatserna från min avhandling.

An Exercise Therapists' Guide to Neuromuscular Exercise for People With Knee or Hip Osteoarthritis

BACKGROUND: Neuromuscular exercise is commonly used in knee injury prevention programs and in rehabilitation following knee injury, and can also be used to address functional impairments is middle-aged and older individuals with knee and hip osteoarthritis (OA). CLINICAL QUESTION: What is neuromuscular exercise for OA? Why should clinicians use it? And how? Nine themes of common questions from exe

Social Differences in Maternal Mortality in Zeeland 1812–1913

Using population reconstructions from linked civil certificates for the province of Zeeland, the Netherlands, for the period 1812–1913, I study the social gradient in maternal mortality. Maternal mortality is defined as deaths in the first 42 days after the birth of a child. Among the women — mother to at least one child and followed between age 20 and 45 — maternal mortality constitutes about one

Sociodemographic disparities in primary care management of back pain in children and young people : a population-based cohort study

Background: Research on the primary care management of back pain in children and young people (CYP) is scarce. Sociodemographic factors may influence presentation and management, potentially contributing to disparities in care and outcomes. This study aimed to describe the management of back pain in CYP and examine associations with sociodemographic characteristics. Methods: Data were extracted fr

Childhood neighborhoods and cause-specific adult mortality in Sweden 1939–2015

The socioeconomic health gradient has widened since the mid-21st century, but the role of childhood neighborhoods remains underexplored. Most neighborhood studies on health are cross-sectional, and longitudinal research is lacking.We analyze how socioeconomic neighborhood conditions in childhood influence cause-specific deaths in adulthood. We use uniquely detailed geocoded longitudinal microdata

Urine and fecal incontinence prevalence is increased in later born 81-year old cohorts in the Swedish general elder population : data from the Good Aging in Skåne study (GÅS)

Background: The prevalence of urinary incontinence (UI) and fecal incontinence (FI) are conditions that increase with age. Apart from few larger studies data on prevalence and severity of UI and FI is scarce, especially among the > 80 yrs. and data of birth cohort effects is lacking. Methods: The purpose of this study was to evaluate birth cohort effects on prevalence of UI and FI in the general o

β-Glucan-Functionalized Nanoparticles Down-Modulate the Proinflammatory Response of Mononuclear Phagocytes Challenged with Candida albicans

Systemic fungal infections are associated with significant morbidity and mortality, and Candida albicans is the most common causative agent. Recognition of yeast cells by immune cell surface receptors can trigger phagocytosis of fungal pathogens and a pro-inflammatory response that may contribute to fungal elimination. Nevertheless, the elicited inflammatory response may be deleterious to the host

Exercise-based cardiac rehabilitation after acute myocardial infarction in Sweden–standards, costs, and adherence to European guidelines (The Perfect-CR study)

Aims: Information on standards including structure- and process-based metrics and how exercise-based cardiac rehabilitation (EBCR) is delivered in relation to guidelines is lacking. The aims of the study were to evaluate standards and adherence to guidelines at Swedish CR centers and to conduct a cost analysis of the physiotherapy-related activities of EBCR. Methods and Results: EBCR standards at

EFFECTS OF INTERNAL COOLANT CROSSFLOW ON FILM-COOLING PERFORMANCE OF DOUBLE-JET AND CYLINDRICAL HOLES

In this paper, the effects of internal coolant crossflow on double-jet holes were simulated and compared with two rows of cylindrical holes under three blowing ratios (M = 0.5, 1.0, and 1.5), with an established and validated turbulence model. The results show that double-jet holes can provide better film cooling performance for the three different blowing ratios compared with cylindrical holes. A

Synthesis and experimental study of improved double perovskite-type PrBaCo2O5+δ materials to produce oxygen-enriched CO2 for oxyfuel combustion application

Perovskite oxides are promising oxygen carrier materials to produce O2/CO2 gas for oxyfuel combustion application. In this study, PrBaCo2O5+δ double perovskite oxide was prepared by the EDTA sol-gel method and first applied as oxygen carrier for oxygen production. The oxygen adsorption/desorption performance of PrBaCo2O5+δ perovskite was carrried out in a fixed-bed set-up. The operating factors of

Ordered arrays of low-dimensional Au and Pd : synthesis and in situ observations

Electrodeposition of metals in templates of nano-porous anodic aluminum oxide (NP-AAO) is a versatile way of fabricating ordered arrays of metal nanowires. Thanks to the self-arranged long-range hexagonal order of the pores, electrodeposition in NP-AAO is an easily scalable bottom-up synthesis route and an attractive alternative to traditional top-down fabrication methods such as electron beam lit

Comparison of fractal and grid electrodes for studying the effects of spatial confinement on dissociated retinal neuronal and glial behavior

Understanding the impact of the geometry and material composition of electrodes on the survival and behavior of retinal cells is of importance for both fundamental cell studies and neuromodulation applications. We investigate how dissociated retinal cells from C57BL/6J mice interact with electrodes made of vertically-aligned carbon nanotubes grown on silicon dioxide substrates. We compare electrod

Pan-cancer analysis of pre-diagnostic blood metabolite concentrations in the European Prospective Investigation into Cancer and Nutrition

Background: Epidemiological studies of associations between metabolites and cancer risk have typically focused on specific cancer types separately. Here, we designed a multivariate pan-cancer analysis to identify metabolites potentially associated with multiple cancer types, while also allowing the investigation of cancer type-specific associations. Methods: We analysed targeted metabolomics data

Pesticide exposure and cortical brain activation among farmworkers in Costa Rica

Background: Previous epidemiological studies have reported associations of pesticide exposure with poor cognitive function and behavioral problems. However, these findings have relied primarily on neuropsychological assessments. Questions remain about the neurobiological effects of pesticide exposure, specifically where in the brain pesticides exert their effects and whether compensatory mechanism

Deviations from the extended London model at high magnetic fields in YBa2Cu3 O7

We report on the evolution with the magnetic field and the temperature of the vortex lattice (VL) in fully oxygenated YBa2Cu3O7 as studied by time-of-flight small-angle neutron scattering. Using the High Field Magnet/Extreme Environment Diractometer beamline at Helmholtz-Zentrum Berlin, we have obtained data up to 25.9 T - much higher than data available previously. Our VL structure results are co