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Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus

Objectives: Adverse pregnancy outcomes are more common in women with SLE compared with healthy women, but we lack prognostic biomarkers. Plasma IFN-α protein levels are elevated in a subgroup of pregnant women with SLE, but whether this is associated with pregnancy outcomes is unknown. We investigated the relationship between IFN-α, adverse pregnancy outcomes and the presence of autoantibodies in

Selective rotation and attractive persistent currents in antidipolar ring supersolids

A repulsively interacting Bose-Einstein condensate on a ring is well known to show persistent currents. For attractive interactions, however, a bound state may form that renders the rotation classical. Here we show that in a multiply connected confinement, the strong in-plane attraction of an antidipolar condensate can form stacks of ring-shaped density lumps which may coherently overlap to form a

Maximal steady-state entanglement in autonomous quantum thermal machines

We devise an autonomous quantum thermal machine consisting of three pairwise-interacting qubits, two of which are locally coupled to thermal reservoirs. The machine operates autonomously, as it requires no time-coherent control, external driving or quantum bath engineering, and is instead propelled by a chemical potential bias. Under ideal conditions, we show that this out-of-equilibrium system ca

Indole-3-propionic acid promotes hepatic stellate cells inactivation

Background & aims: We have previously reported that the serum levels of gut-derived tryptophan metabolite indole-3-propionic acid (IPA) are lower in individuals with liver fibrosis. Now, we explored the transcriptome and DNA methylome associated with serum IPA levels in human liver from obese individuals together with IPA effects on shifting the hepatic stellate cell (HSC) phenotype to inactiv

Simple and general bounds on quantum random access codes

Random access codes are a type of communication task that is widely used in quantum information science. The optimal average success probability that can be achieved through classical strategies is known for any random access code. However, only a few cases are solved exactly for quantum random access codes. In this paper, we provide bounds for the fully general setting of n independent variables,

Compression of Entanglement Improves Quantum Communication

Shared entanglement can significantly amplify classical correlations between systems interacting over a limited quantum channel. A natural avenue is to use entanglement of the same dimension as the channel because this allows for unitary encodings, which preserve global coherence until a measurement is performed. Contrasting this, a distributed task based on a qubit channel is demonstrated, for wh

Being the nurse's eyes and ears : a mixed methods study of assistant nurses' perceptions of their role regarding drug-related problems in nursing homes

BACKGROUND: Insufficient knowledge among assistant nurses (ANs) in nursing homes (NHs) on medicines and drug-related problems (DRPs) in older people causes difficulties in acknowledging the side effects of medications, which can be harmful to the individual and endangers patient safety. The aim of this study was to explore the ANs' thoughts on their professional role in preventing DRPs in NH resid

Information capacity of quantum communication under natural physical assumptions

The quantum prepare-and-measure scenario has been studied under various physical assumptions on the emitted states. Here, we first discuss how different assumptions are conceptually and formally related. We then identify one that can serve as a relaxation of all others, corresponding to a limitation on the one-shot accessible information of the state ensemble. This motivates us to study the optima

The risk for psychiatric disorders in offspring from thrombosis-prone pedigrees in Sweden : a nationwide family study

Background: Psychiatric disorders have been associated with venous thromboembolism (VTE). However, to our knowledge, no nationwide study has examined the familial association between VTE and psychiatric disorders. Objectives: We took a pedigree-based approach and examined the risk of psychiatric disorders in offspring from extended pedigrees according to the densities of VTE in pedigrees. Methods:

Aging towards walkable futures : insights from a multidisciplinary workshop held in Barcelona, Spain

Background: The aging of the world’s population and the increase in sedentary lifestyles are leading to an increase in walking impairments at older ages. Here, we aimed to comprehensively discuss walking in the context of an aging population; and identify and agree on a list of future research priorities and policy actions. Methods: We followed a participatory approach and held a multidisciplinary

Iron insight : exploring dietary patterns and iron deficiency among teenage girls in Sweden

PURPOSE: This observational study examined the relationship between self-reported dietary patterns-omnivore, pescatarian, vegetarian, and vegan-and iron status among Swedish teenage girls. Additionally, we compared the consumption of various food groups in relation to iron status.METHODS: Data were collected from 475 female high school students in Malmö and Lund, Sweden, using questionnaires on di

Bound Entangled States Are Useful in Prepare-and-Measure Scenarios

We show that bipartite bound entangled states make possible violations of correlation inequalities in the prepare-and-measure scenario. These inequalities are satisfied by all classical models as well as by all quantum models that do not feature entanglement. In contrast to the known Bell inequality violations from bound entangled states, we find that the violations in the prepare-and-measure scen

Photon counting statistics in Gaussian bosonic networks

The statistics of transmitted photons in microwave cavities play a foundational role in microwave quantum optics and its technological applications. By utilizing quantum mechanical phase-space methods, we here develop a general theory of the photon counting statistics in Gaussian bosonic networks consisting of driven cavities with beamsplitter interactions and two-mode-squeezing. The dynamics of t

Binarization of multioutcome measurements in high-dimensional quantum correlation experiments

High-dimensional systems are an important frontier for photonic quantum correlation experiments. These correlation tests commonly prescribe measurements with many possible outcomes but they are often implemented through many individual binary-outcome measurements that use only a single-detector. Here, we discuss how this binarization procedure for multioutcome measurements can open a loophole, unl

Zinc and Breast Cancer Survival: A Prospective Cohort Study of Dietary Intake and Serum Levels

Zinc has been suggested to play a role in breast cancer progression; however, no previous study on zinc levels and the potential effect on breast cancer survival has been conducted. This study investigates recurrence-free survival (RFS), breast cancer-specific survival (BCSS) and overall survival (OS) in relation to zinc levels, in serum and diet, overall and stratified for phosphorus and selenium

Growth selectivity control of InAs shells on crystal phase engineered GaAs nanowires

In this work we demonstrate a two-fold selectivity control of InAs shells grown on crystal phase and morphology engineered GaAs nanowire (NW) core templates. This selectivity occurs driven by differences in surface energies of the NW core facets. The occurrence of the different facets itself is controlled by either forming different crystal phases or additional tuning of the core NW morphology. Fi

Opioid use prior to total knee replacement : comparative analysis of trends in England and Sweden

Objectives: To describe and compare trends in the frequency of opioid prescribing/dispensing in English and Swedish patients with osteoarthritis prior to total knee replacement (TKR). Methods: 49,043 patients from an English national database (Clinical Practice Research Datalink) and 5,955 patients from the Swedish Skåne Healthcare register undergoing TKR between 2015 and 2019 were included, along

Polyp Segmentation of Colonoscopy Images by Exploring the Uncertain Areas

Colorectal cancer is one of the leading causes of death worldwide. Polyps are early symptoms of colorectal cancer and prone to malignant transformation. Polyp segmentation of colonoscopy images can help diagnosis. However, existing studies on polyp segmentation of colonoscopy images face two main difficulties: blurry polyp boundaries, close resemblances between polyps and surrounding tissues. The

The association between preexisting conditions and osteoarthritis development in peripheral joints: A population based nested case-control study

AimTo study the risk of receiving a new (incident) osteoarthritis (OA) diagnosis in different joint sites based on conditions diagnosed in the 20 years prior the OA diagnosis.MethodsWe used register data for the entire population of the Skåne region (Sweden) to perform a nested case-control study. The outcome was newly diagnosed (incident) OA in peripheral joints, i.e. knee (ICD-10 code M17), hip