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Lesson enactments : Maintenance in everyday educational practice

This article explores lesson enactments as co-constitutive of human-technology relationality in everyday schooling, rather than neutral backdrops for educational activities. In doing so, the article introduces maintenance as its key concept, drawing on insights from maintenance studies and actor-network theory (ANT). Being both theoretically and empirically informed, maintenance means reconsiderin

Inferring compound heterozygosity from large-scale exome sequencing data

Recessive diseases arise when both copies of a gene are impacted by a damaging genetic variant. When a patient carries two potentially causal variants in a gene, accurate diagnosis requires determining that these variants occur on different copies of the chromosome (that is, are in trans) rather than on the same copy (that is, in cis). However, current approaches for determining phase, beyond pare

Obstetric outcome in women with congenital heart disease : A nationwide cohort in Sweden

INTRODUCTION: Survival and healthcare for patients with congenital heart disease have improved, and the number of pregnancies among women of childbearing age with congenital heart disease has increased. Our aim was to investigate obstetric outcomes in a large retrospective, national registry study of women with congenital heart disease compared to controls.MATERIAL AND METHODS: The study included

Enabling PhD student collaboration in research groups

Independence and collaboration both play crucial roles in PhD students’ research practice and in their socialization into the PhD role. This study examines how theexpectation of PhD students' academic independence intersects with the need for more collaborative engagements within research groups. Drawing on interviews with supervisors and an analysis of co-authorship patterns in PhD studentdissert

Vaccine protection against COVID-19 mortality in relation to time since last booster dose among nursing home residents in Sweden - A case-control study over 35 months

BACKGROUND: The implementation of COVID-19 vaccination among older persons at nursing homes has lowered the infection-associated mortality considerably, but emerging virus variants and decline in vaccine-induced immunity over time necessitate examination of future booster dosing strategies. The overall aim of this study was to assess vaccine protection against COVID-19 mortality in relation to tim

Brain Tumor Characterization Using Multibiometric Evaluation of MRI

The aim was to evaluate volume, diffusion, and perfusion metrics for better presurgical differentiation between high-grade gliomas (HGG), low-grade gliomas (LGG), and metastases (MET). For this retrospective study, 43 patients with histologically verified intracranial HGG (n = 18), LGG (n = 10), and MET (n = 15) were chosen. Preoperative magnetic resonance data included pre- and post-gadolinium co

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Circulating proteins are vital in human health and disease and are frequently used as biomarkers for clinical decision-making or as targets for pharmacological intervention. Here, we map and replicate protein quantitative trait loci (pQTL) for 90 cardiovascular proteins in over 30,000 individuals, resulting in 451 pQTLs for 85 proteins. For each protein, we further perform pathway mapping to obtai

Right ventricular function parameters in pulmonary hypertension: echocardiography vs. cardiac magnetic resonance

BackgroundRight ventricular (RV) function is a major determinant of outcome in patients with pulmonary hypertension. Cardiac magnetic resonance (CMR) is gold standard to assess RV ejection fraction (RVEFCMR), however this is a crude measure. New CMR measures of RV function beyond RVEFCMR have emerged, such as RV lateral atrio-ventricular plane displacement (AVPDlat), maximum emptying velocity (S’C

DN Debatt. ”Digitaliserad socialtjänst kan lösa framtidens behov”

Denna debattartikel argumenterar för att socialt arbete och socialtjänst behöver utvecklas i förhållande till digitalisering. Som ett led i ett samarbetsprojekt mellan Lunds universitet och Helsingborg stad, finansierat av både Vinnova och Helsingborg stad, skriver företrädare för både universitet och stad en debattartikel i DN. Hur kan socialtjänsten utvecklas med hjälp av digitalisering - nu och

The states of water in Norway spruce (Picea abies (L.) Karst.) studied by low-field nuclear magnetic resonance (LFNMR) relaxometry : Assignment of free-water populations based on quantitative wood anatomy

Low-field nuclear magnetic resonance (LFNMR) relaxometry was applied to determine the spin-spin relaxation time (T2) of water-saturated Norway spruce (Picea abies (L.) Karst.) specimens cut from mature sapwood (sW) and mature and juvenile heartwood (hW), where earlywood (EW) and latewood (LW) were separated. In combination with quantitative wood anatomy data focusing on the void volumes in various

Size-based sorting of dynamic bacterial clusters

Group A Streptococcus (GAS) forms highly deformable aggregates with broad variations in size and morphology, complicating controlled separation and biological analysis. Reliable methods to isolate fractions of GAS clusters with defined properties are essential for studying host–pathogen interactions that depend on cluster size. Here, we present a simple deterministic lateral displacement (DLD) mic

Weight trajectories and obesity onset between 17 and 60 years of age, and cause-specific mortality: the Obesity and Disease Development Sweden (ODDS) pooled cohort study

BackgroundLongitudinal data on weight change, its timing, and the age of obesity onset in relation to cause-specific mortality are limited.MethodsFrom ODDS, a nationwide pooled cohort study in Sweden, we included 258,269 men and 361,784 women with at least three weight assessments between ages 17 and 60, collected in 1963–2015. We applied linear mixed-effects models to estimate weight trajectories

Sound of democracy : Towards the democratisation of standards for soundscapes​

With this audio paper, our aim is to explore the connection between sound and democracy. Recognizing the multifaceted nature of this field, we approach it through the notion of care and an empirical analysis of the democratic implications of trying to regulate sound in public spaces. We examine ISO standards as one example of the many attempts to control sound in both public and private spaces. St

Markfuktighetens påverkan på granens tillväxt i Guvarp

Populärvetenskaplig sammanfattning: Drunkningsrisk för skogen? Att mängden vatten i marken är viktig för att granen ska kunna ha så god tillväxt som möjligt är ingen nyhet. Är det för fuktigt drunknar rötterna, på grund av att de inte får en tillräckligt mycket syre. I denna studie har två markberedningsmetoder, högläggning och ingen markberedning, jämförts för att se vilket alternativ som är mestNorway spruce is a coniferous tree with many different fields of application. For an example, they are used as Christmas trees, decoration and as timber or pulpwood. The reason why many foresters in Sweden tend to choose spruce as their main species for plantation is partly because of their fast growth rate and partly because the main products are derived from the actual tree trunks. In the forest

Allochthonous and autochthonous carbon sources of lake bacterioplankton

Popular Abstract in Swedish Pelagiska bakterier använder löst organiskt material som kol- och energikälla. Det lösta materialet kan ha sitt ursprung i intern (autokton) eller terrester (allokton) primärproduktion. Den här avhandlingen handlar om hur bakterier använder autoktont och alloktont producerat kol. Dessutom undersöker jag om det finns en koppling mellan kolkällans ursprung och strukturen Organic substrates for pelagic bacteria are derived from dissolved organic carbon (DOC) in the water column that originates either from primary production from within the lake itself (autochthonous), or import of organic matter from the terrestrial watershed (allochthonous production). This thesis addresses the utilization of allochthonous versus autochthonous carbon (C) sources by lake bacteriopl

Stable Peptide of the Endogenous Opioid Enkephalin Precursor and Breast Cancer Risk.

In experimental studies, enkephalins (ENKs) and related opioids have been implicated as negative regulators of breast cancer development by enhancing immune-mediated tumoral defense as well as directly inhibiting cancer cells. We hypothesized that plasma levels of ENKs are predictive of the long-term breast cancer risk. Therefore, our objective was to measure pro-ENK A, a surrogate for mature ENK,