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The effects of the physical-spatial-technical environment on aging well have been overlooked both conceptually and empirically. In the spirit of M. Powell Lawton's seminal work on aging and environment, this article attempts to rectify this situation by suggesting a new model of how older people interact with their environment. Goals of the paper include (a) integration of the essential elements o

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Engaging old users in the exploration of future product concepts can be challenging. It is of great value to find ways to actively involve them in the design of novel technologies intended for them, particularly when they have no prior experience of the technology in question. One obstacle in this process is that many old people do not identify themselves as being old or they think that it (the te

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The lithium salt of 2,6-difluoro-2′-sulfobenzophenone was conveniently synthesized in one-pot by reacting 2,6-difluorophenyllithium with 2-sulfobenzoic acid cyclic anhydride in THF at −70 °C whereafter the product crystallized out of solution. A poly(arylene ether) and a poly(arylene sulfide) were prepared by polycondensation reactions to demonstrate the reactivity and efficacy of this new monomer

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Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features seen on neuroimaging include recent small subcortical infarcts, lacunes, white matter hyperintensities, perivascular spaces, microbleeds, and brain atrophy. SVD can present as a stroke or cognitive decline, or can have few or no symptoms. SVD frequently coexists with neurodegenerative disease, and can exacerbate cogn

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This article presents a polar diagram method developed for describing and evaluating the potential machinability of different workpiece materials. The potential machinability is examined in terms of five critical properties of the workpiece material. Two groups of materials, a group of common steel grades and the other a group of stainless steels, were examined in detail, their polar diagrams illu

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Purpose – The aim of this study is to test the assumption that ability to handle communication and liability of newness (LoN) is enhanced by academic entrepreneurship education and/or previous start‐up experience. Design/methodology/approach – The data collection includes a questionnaire with a total sample of 392 responding entrepreneurs in Sweden. Statistical analyses are made between entrepren

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Accounting for bioenergy's carbon dioxide (CO2) emissions, as done under the Kyoto Protocol (KP) and European Union (EU) Emissions Trading Scheme, fails to capture the full extent of these emissions. As a consequence, other approaches have been suggested. Both the EU and United States already use value-chain approaches to determine emissions due to biofuels - an approach quite different from that

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The limit of detection of low-molecular weight compounds in tissue sections, analyzed by matrix assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI), was significantly improved by employing sample washing using a pH-controlled buffer solution. The pH of the washing solutions were set at values whereby the target analytes would have low solubility. Washing the tissue sections

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The nexus of population growth and changing diets has increased the demands placed on agriculture to supply food for human consumption, animal feed and fuel. Rising incomes lead to dietary changes, from staple crops, towards commodities with greater land requirements, e.g. meat and dairy products. Despite yield improvements partially offsetting increases in demand, agricultural land has still been

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Understanding the role of electrostatics in protein stability requires knowledge of these interactions in both the folded and unfolded states. Electrostatic interactions can be probed experimentally by characterizing ionization equilibria of titrating groups, parameterized as pK(a) values. However, pK(a) values of the unfolded state are rarely accessible under native conditions, where the unfolded

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The main objective of this study was to investigate the risk of type 1 diabetes mellitus (T1D) in children exposed to tobacco smoking in utero, also taking genetic predisposition as expressed by HLA haplotype into account. In Skåne, the southernmost county of Sweden, all children born 1999-2005 who developed T1D were registered, resulting in 344 cases. For each child with T1D, three control childr

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The neural correspondence between the systems responsible for the execution and recognition of actions has been suggested both in humans and non-human primates. Apart from being a key region of this visuo-motor observation-execution matching (OEM) system, the human inferior frontal gyrus (IFG) is also important for speech production. The functional overlap of visuo-motor OEM and speech, together w

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Androgen deprivation therapy (ADT) is first-line treatment for metastatic prostate cancer (PCa). Gonadotrophin-releasing hormone (GnRH) agonists are the most commonly used ADT but have several theoretical physiologic disadvantages (e.g. initial testosterone surge, potential microsurges upon repeat administration). Testosterone surge delays the intended serologic endpoint of testosterone suppressio

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Human aquaporin 2 (AQP2) is a water channel found in the kidney collecting duct, where it plays a key role in concentrating urine. Water reabsorption is regulated by AQP2 trafficking between intracellular storage vesicles and the apical membrane. This process is tightly controlled by the pituitary hormone arginine vasopressin and defective trafficking results in nephrogenic diabetes insipidus (NDI

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Scholarly discourses on energy security have developed in response to initially separate policy agendas such as supply of fuels for armies and transportation, uninterrupted provision of electricity, and ensuring market and investment effectiveness. As a result three distinct perspectives on energy security have emerged: the `sovereignty' perspective with its roots in political science; the `robust

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The nitrogen (N) cycle contains two different processes of dissimilatory nitrate (NO(3)(-)) reduction, denitrification and dissimilatory NO(3)(-) reduction to ammonium (DNRA). While there is general agreement that the denitrification process takes place in many soils, the occurrence and importance of DNRA is generally not considered. Two approaches have been used to investigate DNRA in soil, (1) m

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We present a calculation of the finite volume corrections to meson masses and decay constants in three flavour Partially Quenched Chiral Perturbation Theory ( PQChPT) through two-loop order in the chiral expansion for the flavour-charged ( or off-diagonal) pseudoscalar mesons. The analytical results are obtained for three sea quark flavours with one, two or three different masses. We reproduce the

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We report on a full-Holocene pollen, charcoal and macrofossil record from a small forest hollow in Gribskov, eastern Denmark. The Fagus sylvatica pollen record suggests the establishment of a small Fagus population at Gribskov in the early Holocene together with early establishment of other thermophilous broadleaved trees, including Quercus sp., Tilia sp. and Ulmus sp. The macrofossils contribute

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In this work, we report for the first time the rotational coherent anti-Stokes Raman spectroscopy (CARS) spectrum of water vapor, recorded through experiments at 400K and 670K for Raman shifts up to 600cm(-1). Using the standard dual-broadband pure rotational CARS approach, the resonant structure was overwhelmed by a strong non-resonant background. By employing a polarization technique, this backg

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Neutron-rich ^{96,98}Sr isotopes have been investigated by safe Coulomb excitation of radioactive beams at the REX-ISOLDE facility. Reduced transition probabilities and spectroscopic quadrupole moments have been extracted from the differential Coulomb excitation cross sections. These results allow, for the first time, the drawing of definite conclusions about the shape coexistence of highly deform