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BACKGROUND: Patients diagnosed with Crohn disease (CD) are known to be at an increased risk of bowel cancers and lymphoma. CD is an autoimmune disease and we hypothesize that the patients are predisposed to a wider spectrum of cancers.PATIENTS AND METHODS: A CD research database was constructed by identifying hospitalized CD patients from the Hospital Discharge Register and cancer patients from th
In the licentiate thesis, it is researched and analyzed how sustainability criteria may be used in a legal framework, with the purpose to promote and safeguard sustainable products and their production. The research and analysis are conducted on the basis of the EU approach to use sustainability criteria for biofuels in the transport sector, legally expressed in Directive 2009/28/EC, and its amend
Reduction of trans-[Pt(CN)4 X2]2- (X = Cl or Br) as model compounds for antitumour-active platinum(IV) pro-drugs, to [Pt(CN)4]2- by L-methionine, MeSR, has been studied at 25 °C in the range 0 < pH < 12 (X = Cl) and 0 < pH < 6 (X = Br) by use of stopped-flow spectrophotometry. The stoichiometry is [Pt IV] : [MeSR] ≈ 1 : 1; the reaction products are methionine S-oxide and [Pt(CN)4]2- as identified
Large software organizations with a product line development approach face many challenges regarding testing. Test managers need to make tradeoffs along three dimensions of repeated testing (abstraction level, time and product space) and consider a range of goals and constraints. In order to keep pace with the decreased development time for new products, which is enabled by the systematic reuse, s
Problem: Groin pain is common in soccer players but the prevalence has only been examined in uncontrolled studies. Methods: 479 male soccer players aged 25 years (17 - 43) (mean with range), 144 female soccer players aged 23 years (16 - 47), 74 men with no history of soccer training aged 26 years (16 - 42) and 94 women with no history of soccer training aged 23 years (range 15 - 43) answered a mai
Popular Abstract in English The concern about pollutant emissions from combustion devices has stimulated the development of modern combustion devices. As one of the major power generation machines, modern gas turbine engine has been designed to run at fuel-lean and premixed mode of combustion in which the combustion temperature is moderate so that NOx emission is low. Combustion in premixed mode rThis thesis deals with the physics of turbulent swirling flows. Large eddy simulation (LES) method is used to investigate the vortex breakdown process, the precessing vortex core (PVC), and the effect of swirl number and flow field configuration on swirling flows. The study is based on an open source CFD code, \textit{OpenFoam}. Turbulent swirling flows are widely used in combustion devices such a
Abstract Objectives: The area of regenerative work is still close to unexplored. The aim was to explore the possibility for employees to gain energy at work. Methods: Questionnaire to all employees (n = 599) from different professions in public and private primary health care centers in one health care district in Sweden. The questionnaire, which had a salutogenic perspective, included information
Forest ecosystems, covering over a third of land on the Earth, play a significant role in the global hydrological cycle, and influence soil erosion and climate change. However, the distribution, movements, quality of water, and hydrological processes in forested ecosystems are not well understood yet. This thesis aims to improve our understanding of the interaction between forest ecosystems and waForest ecosystems, covering over a third of land on the Earth, play a significant role in the global hydrological cycle, and influence soil erosion and climate change. However, the distribution, movements, quality of water, and hydrological processes in forested ecosystems are not well understood yet. This thesis aims to improve our understanding of the interaction between forest ecosystems and wa
Background: There is a great unmet clinical need to identify patients with thin primary cutaneous melanomas (T1, Breslow thickness ≤ 1 mm) who have a high risk for tumor recurrence and death from melanoma. Kin of IRRE-like protein 1 (KIRREL/NEPH1) is expressed in podocytes and involved in glomerular filtration, but its expression in human cancer has not yet been reported. Screening in the Human Pr
Background: After neoadjuvant chemotherapy (NAC), about 20% of pts with muscle-invasive UC are found to have advanced pT-stage or lymph node involvement and 5-year overall survival (OS) of them is < 30%. Tumor samples from these pts may provide information about chemotherapy resistance, and may predict for the activity of new drugs given postoperatively. Alterations of FGFR3 gene represent a thera
PURPOSE: Graft failure in heart transplant recipients is still the leading cumulative cause of death, rejection related injuries likely being an important contributor. In this study we used a genome-wide association approach using whole-genome data from chromosome 6 to analyze genetic associations with survival after heart transplantation. METHODS: The study included recipient samples from patient
PURPOSE: To investigate the survival of heart transplant (HTx) recipients during different time periods in Sweden. We hypothesized that the survival for HTx recipients has improved following advancements in the management of these patients. METHODS: Data was obtained through the database of the organ exchange organization Scandiatransplant. All patients who underwent HTx in Sweden between Jan 1988
Discussion on social media and their contribution to democratisation is dominated by scholarship on the use of social media in mobilizing and coordinating grassroots opposition in contentious movements (e.g., the Arab Spring). Such approach, however, fails to recognize the power dynamics underlying everyday uses of social media. To fill this gap, this article provides one of the first studies on t
Our current patterns of resource use have serious impact on the environment and are affecting our chances to future welfare. In this context, circular economy practices emerge as essential. Circular economy focuses on maximizing resource efficiency through reuse, repair, recycling, and product longevity—ultimately minimizing waste and reducing reliance on virgin materials. My dissertation presents
From June to November 1945, over 70 shipments of flat-packed architectural elements arrived at the harbours of Nexø and Rønne on the Danish island Bornholm. The shipments consisted of prefabricated interior fixtures and ready-to-be mounted walls. The Danish municipality prepared infrastructure, named new roads, and within a year, 300 wooden houses were assembled on site. The buildings, SvenskehuseFrom June to November 1945, over 70 shipments of flat-packed architectural elements arrived at the harbours of Nexø and Rønne on the Danish island Bornholm. The shipments consisted of prefabricated interior fixtures and ready-to-be mounted walls. The Danish municipality prepared infrastructure, named new roads, and within a year, 300 wooden houses were assembled on site. The buildings, Svenskehuse
Domain-specific languages are used in numerous problem domains, e.g. database handling, robot programming and numerical calculations. The main advantage of using such languages is the ease with which a problem within the domain can be expressed in the language. The resulting programs are easier to debug and maintain, and consist of higher quality code since the language constructs are close to the
Butterflies have been systematically monitored in Europe for several decades using standard protocols that are now adopted in over 30 countries. Butterflies are ideal biological indicators: they are well-documented, measurable, sensitive to environmental change, occur in a wide range of habitat types, represent many other insects, and are popular with the public because of their beauty. Records fr
This dissertation is set in the context of the modern space age, which is characterised by an overall increase in space activities on a global scale and a relative increase in private and commercial space activities. Space has become a business case.This study analyses the principle of international responsibility for activities in outer space as mainly codified in Article VI of the Outer Space Tr
Brevmall Address: Telephone +46-40-391058 CRC (Clinical Research Center) Telefax +46-40-391212 Jan Waldenströms gata 35, building 91, level 12 E-mail maria.gomez@med.lu.se S-21428 Malmö, Homepage http://www.ludc.lu.se/ Sweden Internpost Hs 36 Datum 2018-04-16 Ärende: LUDC konfokal plattform Följande mikroskop ingår i plattformen: Ett Zeiss LSM 800 with Airyscan som köptes hösten 2017 i utbyte mot
Brevmall Address: Telephone +46-40-391058 CRC (Clinical Research Center) Telefax +46-40-391212 Jan Waldenströms gata 35, building 91, level 12 E-mail maria.gomez@med.lu.se S-21428 Malmö, Homepage http://www.ludc.lu.se/ Sweden Internpost Hs 36 Datum 2018-04-04 Ärende: LUDC konfokal plattform Följande mikroskop ingår i plattformen: Ett Zeiss LSM 800 with Airyscan som köptes hösten 2017 i utbyte mot
https://www.ludc.lu.se/sites/ludc.lu.se/files/kontrakt_konfokal_plattform_5_april_2018.pdf - 2026-06-28
