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Site localisation on bacterial surface proteins using super resolution imaging

I snart 500 år har människan använt sig av diverse optiska instrument för att betrakta sådant som inte är möjligt att se med blotta ögat. Teleskop har använts för att studera himlakroppar och mikroskop för att exempelvis undersöka små biologiska beståndsdelar. Det finns idag många olika metoder inom optisk mikroskopi men samtliga följer en liknande grundprincip. Objektet som ska avbildas exponerasSeveral significant pathogenic bacteria exhibit surface proteins that bind human antibodies, preventing them from being recognized by the human immune system. These bacteria are thus protected from elimination and can survive in the host organism. One common such bacteria is the Streptococcus pyogenes that exhibits the antibody binding M protein on its surface. Streptococcus pyogenes causes more t

Comics’ and graphic novels’ effect on the perception of climate change and natural disasters

There is a paucity of research in the field of communicating disasters and climate change through comics and the effect sequential art has on the perception of these two subjects. Increasingly, communication through comics is becoming very trendy, and a few studies demonstrate evidence that comics have effects on the people’s perception of complex matters. In order to extend our understanding of w

Den nya generationens preferenser för employer branding - En kvalitativ studie med kommunikationsstudenter på svenska universitet

Denna studie syftar till att öka kunskapen om hur organisationer kan använda em-ployer branding i sin kommunikation för att attrahera ny talang. Tidigare forskning kring extern employer branding är huvudsakligen fokuserad på arbetskraft som redan är etablerad på arbetsmarknaden, och dessutom finns mycket få studier i en svensk kontext. För att bidra till ökad kunskap i strategisk kommunikation ochThis study aims to increase the knowledge of how organizations can use employer branding communication to attract new talent. Previous research on external em-ployer branding has been mainly focused on employees already established on the labour market and there are very few studies performed in a Swedish context. To contribute to increased knowledge in the field of strategic communication and em-

Confirmed association between neonatal phototherapy or neonatal icterus and risk of childhood asthma

We have previously demonstrated an association between neonatal phototherapy and/or neonatal icterus and risk of hospitalization for childhood asthma. This study included children who were prescribed anti-asthmatic medication on a population basis to study exposures during the foetal and neonatal period and risk of childhood asthma. The Swedish Medical Birth Register was linked to the Swedish Pres

Mallomonas pseudocoronata Prescott (Synurophyceae), a recent arrival in Scania, southern Sweden?

Since the early 1960s, water chemistry and phytoplankton have been monitored in several lakes in Sweden. However, as early as 1900-1901, the German algologist Lemmermann investigated phytoplankton from lakes in Scania, southern Sweden. Several phytoplankton samples from these investigations were preserved and saved, and are deposited at the Department of Ecology in the University of Lund. These ol

Ultrafast Excited State Dynamics of 5,6-Dihydroxyindole, A Key Eumelanin Building Block: Nonradiative Decay Mechanism.

As part of a program designed to elucidate the excited state properties of key eumelanin building blocks, we report herein a study of 5,6-dihydroxyindole (DHI) in phosphate buffer at pH 3 and pH 7 using femtosecond transient absorption spectroscopy. The transient absorption changes following excitation at 266 nm were used to directly monitor relaxation of the excited states. It was found that the

Register studies of cancer in the Southern Health Care Region in Sweden

Popular Abstract in Swedish Södra Regionvårdsnämnden har önskat att få belyst om vi har en rättvis och jämlik cancervård i Södra sjukvårdsregionen. Därför har en populationsbaserad registerstudie med många olika etapper genomförts. Basinformationen har hämtats från Tumörregistret i Södra sjukvårdsregionen. Första diagnosdatum noterades och hemort (kommun, distrikt, län) samt sjukhus definierades eThe overall aim was to study different aspect of health care use and health care costs on a population based level for persons with cancer and their partners, and from an individual level to explore the impact of comorbidities in incidence and survival. In the beginning of the study all persons in the Southern Health Care Region in Sweden diagnosed with colon, rectal, breast, prostate and lung can

Application of enzymes, sodium tripolyphosphate and cation exchange resin for the release of extracellular polymeric substances from sewage sludge - Characterization of the extracted polysaccharides/glycoconjugates by a panel of lectins

The study describes extraction of extracellular polymeric substances (EPS) from sewage sludge by applying enzymes and enzymes combined with sodium tripolyphosphate (STPP). Additionally, a systematic study of two non-enzymatic extraction agents is described. The assessment of the released products is made by colorimetrical methods and polysaccharides/glycoconjugates identification by the interactio

Budd-Chiari syndrome in Sweden: epidemiology, clinical characteristics and survival - an 18-year experience

The exact incidence and prevalence of Budd-Chiari syndrome (BCS) is unknown in the general population. Published reports differ in terms of the clinical characteristics, effects of therapy and survival. To investigate the epidemiology, clinical presentation and survival in patients with BCS. Retrospective multicentre study in Sweden reviewing the medical records of all patients with BCS 1986-2003,

A Leukotriene A(4) Hydrolase-Related Aminopeptidase from Yeast Undergoes Induced Fit upon Inhibitor Binding.

Vertebrate leukotriene A(4) hydrolases are bifunctional zinc metalloenzymes with an epoxide hydrolase and an aminopeptidase activity. In contrast, highly homologous enzymes from lower organisms only have the aminopeptidase activity. From sequence comparisons, it is not clear why this difference occurs. In order to obtain more information on the evolutionary relationship between these enzymes and t

The 14-3-3 protein family - Conserved structure, diverse functions

While once abstruse, 14-3-3 proteins are now well known as players in several cellular processes. These processes range from apoptosis and mitosis in mammals and yeast, to regulation of primary metabolism in plants. To date, 104 proteins have been shown to interact with 14-3-3s of which 85 are found in mammals and yeast, and 21 are found in plants. Their consensus action is to bind to phosphorylat

Processing of raw Cassava (Manihot esculenta) - Experiments and Modelling.

The objective of the present thesis was to understand how the quality and performance of dried cassava products could be developed by drying and other processing steps. This goal was achieved in several stages. First, a survey of the composition of six cassava varieties from Bolivia, was performed, which resulted in the report of chemical and mineral compositions of the tubers. The mineral composi

Protein-RNA interplay in translation. Structural studies of RRF, SelB and L1.

Popular Abstract in Swedish Allt levande består till stor del av proteiner. De bygger upp muskler och hår, transporterar syre i blodet och ser till att kemin i kroppen fungerar som den ska. Men hur tillverkas då dessa proteiner? Jo i alla celler finns ribosomer, proteinfabriker. En bakterieribosom är ungefär 0.02 mikrometer stor. Den är sammansatt av proteiner och RNA-kedjor. RNA utgör den funktioTranslation is a central biological process, that is catalysed by a machinery consisting of RNA and protein. In this thesis three different protein components of the bacterial protein synthesis system have been structurally studied. Ribosome recycling factor (RRF) is essential for the recycling step of the translation cycle, elongation factor SelB is a specialised elongation factor needed for co-t

The Biblical Odes and the Text of the Christian Bible : A Reconsideration of the Impact of Liturgical Singing on the Transmission of the Gospel of Luke

Sung in Christian liturgies from the earliest period, biblical Odes—a set of songs excerpted from the biblical and apocryphal books—were central to emerging Christian practices and texts, yet their significance as textual witnesses has rarely been studied. Overlooked by text critics and editors, the Odes have largely been omitted from contemporary critical editions of the biblical books, including

Convergent patterns of long-distance nocturnal migration in noctuid moths and passerine birds.

Vast numbers of insects and passerines achieve long-distance migrations between summer and winter locations by undertaking high-altitude nocturnal flights. Insects such as noctuid moths fly relatively slowly in relation to the surrounding air, with airspeeds approximately one-third of that of passerines. Thus, it has been widely assumed that windborne insect migrants will have comparatively little

Magnetization transfer imaging for polymer gel dosimetry

Off-resonance RF pre-saturation was used to obtain contrast in MRI images of polymer gel dosimeters irradiated to doses up to 50 Gy. Two different polymer gel dosimeters composed of 2-hydroxyethyl-acryl ate or methacrylic acid monomers mixed with N, N'-methylene-bisacrylamide (BIS), dispersed in an aqueous gelatin matrix were evaluated. Radiation-induced polymerization of the co-monomers generates