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5-Year Outcomes of PCI Guided by Measurement of Instantaneous Wave-Free Ratio Versus Fractional Flow Reserve

Background: Instantaneous wave-free ratio (iFR) is a coronary physiology index used to assess the severity of coronary artery stenosis to guide revascularization. iFR has previously demonstrated noninferior short-term outcome compared to fractional flow reserve (FFR), but data on longer-term outcome have been lacking. Objectives: The purpose of this study was to investigate the prespecified 5-year

The effect of two midwives during the second stage of labour to reduce severe perineal trauma (Oneplus): a multicentre, randomised controlled trial in Sweden

BackgroundSevere perineal trauma (SPT) affecting the anal sphincter muscle complex is a serious complication following childbirth, associated with short-term and long-term maternal morbidity. Effective preventive strategies are still scarce. The aim of the Oneplus trial was to test the hypothesis that the presence of a second midwife during the second stage of labour, with the purpose of preventin

The impact of different fixatives on immunostaining of lung adenocarcinomas in pleural effusion cell blocks

BACKGROUND: Cell blocks (CBs) are widely used for biomarker analyses such as immunostaining. Although immunohistochemistry on formalin-fixed paraffin-embedded tissues is standardized, there are multiple preparation methods and fixatives for cytology. Our objective was to investigate the effect of different common fixatives on the immunoreactivity of pleural effusion CBs with metastatic lung adenoc

Effectiveness of a Web-Based Individual Coping and Alcohol Intervention Program for Children of Parents With Alcohol Use Problems : Randomized Controlled Trial

Background: Children whose parents have alcohol use problems are at an increased risk of several negative consequences, such as poor school performance, an earlier onset of substance use, and poor mental health. Many would benefit from support programs, but the figures reveal that only a small proportion is reached by existing support. Digital interventions can provide readily accessible support a

The GABAA Receptor as Target for Novel Heterocyclic Compounds

Ligands for the benzodiazepine-binding site of the GABAA receptor can belong to structurally diverse classes of compounds including, in spite of the name of the binding site, many non-benzodiazepine structures. The GABAA receptor is a ligand-gated ion channel assembled of five subunits from eight different classes with multiple isoforms. The physiological effect elicited by benzodiazepines is beli

Justitia et Prudentia. Rättsbildning genom rättstillämpning - Svea hovrätt och testamentsmålen 1640-1690

Popular Abstract in Swedish Ordet ”testamente” omnämndes för första gången i svenska sammanhang vid mitten av 1100-talet. Under medeltiden användes testamentet huvudsakligen för gåvor till kyrkan, men under 1600-talet förändrades synen på testamentet. Upprättandet av ett testamente blev istället, precis som idag, en möjlighet för den enskilde att själv bestämma över fördelningen av den egna egendoThe purpose of this doctoral dissertation is to investigate how legal issues relating to the law of wills were handled in the clash between the demands on the legal infrastructure of late 17th century Sweden on the one hand, and the insufficiencies of the medieval Swedish legislation on the other. The focus of the study is the law of wills, and how the absence of written law was handled by the app

Krigets sociologi: : Analyser av krigsvåld, koncentrationsläger, offerskap och försoning

I tidigare forskning om krig presenteras ofta ensidiga bilder av fenomenen krigsvåld, offerskap och försoning. Denna bok utgår från berättelser av överlevande efter kriget i Bosnien under 1990-talet. Syftet är att analysera hur de intervjuade beskriver dessa fenomen samt vilka diskursiva mönster som framträder i konstruktionen av begreppen ”offer” och ”förövare”. Mina frågeställningar är: Hur beskThis book analyzes verbally depicted experiences of survivors from the war in Bosnia and Herzegovina. One purpose to describe how the actors portray the social phenomenon of “war violence” “victimhood” and “reconciliation”, and the second aim is to analyze discursive patterns that emerges in the creation of the terms “victim” and “perpetrator”. My research questions are: (1) How do the interviewee

Persistent disabling breathlessness in chronic obstructive pulmonary disease

Objective: To determine the prevalence, change in breathlessness status over time, and risk factors for disabling and persistent disabling breathlessness in relation to treatments in chronic obstructive pulmonary disease (COPD). Materials and methods: Longitudinal analysis of data from the Swedish National Register of COPD with breathlessness measured using modified Medical Research Council (mMRC)

Influence of beliefs about health and illness on self-care and care-seeking in foreign-born people with diabetic foot ulcers : Dissimilarities related to origin

Objective: To describe beliefs about health and illness among foreign-born people with diabetic foot ulcers that might affect selfreported self-care and health-care seeking and to study whether there are dissimilarities related to origin. Method: Qualitative descriptive study. Semi-structured interviews with people aged 38-86 years; 13 born in European and 13 in non-European countries (all except

Measuring floodplain spatial patterns using continuous surface metrics at multiple scales

Interactions between fluvial processes and floodplain ecosystems occur upon a floodplain surface that is often physically complex. Spatial patterns in floodplain topography have only recently been quantified over multiple scales, and discrepancies exist in how floodplain surfaces are perceived to be spatially organised. We measured spatial patterns in floodplain topography for pool 9 of the Upper

Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's disease

BACKGROUND: The discovery that heterozygous missense mutations in the gene encoding triggering receptor expressed on myeloid cells 2 (TREM2) are risk factors for Alzheimer's disease (AD), with only the apolipoprotein E (APOE) ε4 gene allele conferring a higher risk, has led to increased interest in immune biology in the brain. TREM2 is expressed on microglia, the resident immune cells of the brain

Olika kommuner: olika eftervård? En jämförande studie av hur tre kommuner definierar och arbetar med eftervård efter LVM.

Aftercare is an important condition for the Care of Alcoholics and Drug Abuse Act (LVM) to be successful. According to the law, the municipals are responsible for the aftercare. We compared how three municipal in Skåne, Sweden, define and work with the aftercare after treatment under LVM. The study was based on nine qualitative interviews with social workers, division managers and politicians from

Huvudsakligen affärsmässigt motiverat - En analys av begreppets betydelse i 24 kap inkomstskattelagen

I sitt arbete mot att förhindra skatteplaneringsförfaranden har lagstiftaren i inkomstskattelagen infört begränsningar mot rätten till att dra av ränteutgifterna för koncerninterna lån. Vid lagstiftningens införande kom detta endast att gälla lån som hänförde sig till förvärv av delägarrätter men då lagstiftningens syfte inte ansågs uppnås utvidgades reglerna till att omfatta alla interna lån. LagIn the legislator’s work towards preventing tax evasion, the legislator introduced restrictions against deduction of interest expenses relating to inter corporate loans. At first, the adjudication process only applied to loans that were attributable to the acquisition of ownership rights within the corporation. But when the purpose of the law was not considered to be achieved, the legislation was

Microsoft Word - Free-riding in Group Work.doc

Microsoft Word - Free-riding in Group Work.doc Abstract — Studies have shown that group work offers great possibilities for deeper learning compared to some more traditional teaching formats [1], but it can also lead to some new problems such as free-riding. Different aspects of group psychology and behaviour as well as impropriate group sizes can be used to explain why and how free-riding develop

https://www.lth.se/fileadmin/lth/genombrottet/konferens2006/p_o_b_rjesson_mfl.pdf - 2026-06-09

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Centre fo r Theology and Re l ig ious Stud ies CTR R17 Required Reading Required reading for CTR R17 Law and Religion in Judaism, Christianity and Islam, 15 ECTS credits, Spring Semester 2025 as approved by the Director of Studies on 10 December 2024 Books Abou El Fadl, Khaled, Ahmad Atif Ahmad & Said Fares Hassan (eds.), Routledge Handbook of Islamic Law (London: Routledge, 2019), chs. 6, 7, 15,

https://www.ht.lu.se/media/utbildning/dokument/kurser/CTRR17/20251/CTR_R17_Required_Reading.pdf - 2026-06-11

Digital Components Of Thesis Defences Within The Faculty Of Science Third-cycle Programmes

Digital components of thesis defences within the Faculty of Science’s third-cycle programmes Page 1 of 5 Dean DECISION Reg. No. U 2022/133 Date 2022-03-02 Digital components of thesis defences within the Faculty of Science’s third- cycle programmes Background On 24 February 2022, the Vice-Chancellor approved Regulations for Digital Components at the Public Defence of Doctoral Theses at Lund Univer

https://www.science.lu.se/internal/sites/science.lu.se.internal/files/2024-08/Digital%20components%20of%20thesis%20defences%20within%20the%20Faculty%20of%20Science%20third-cycle%20programmes.pdf - 2026-06-20

Business and Human Rights Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian

Business and Human Rights Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Progr

https://rwi.lu.se/news-categories/business-and-human-rights/ - 2026-06-20