Filtyp
Interstitial laser thermotherapy (ILT) is an attractive form of local therapy against cancer because of its anti-tumor immune activity. The aim of this work was to evaluate ILT in breast cancer with respect to technique, changes in tissue immunocompetent cells and effect on prognosis. The method is dependent on accurate assessment of the tumor, and another aim was therefore to evaluate if MRI is b
Adequate circulating blood volume is a prerequisite for circulatory stability. Fluid therapy aims at correcting hypovolaemia, and is an important part of the haemodynamic management of perioperative and critically ill patients. The efficacy of plasma volume substitution largely depends on the pharmacological properties of the colloid solutions used. However, according to the 2-pore theory for tran
Popular Abstract in Swedish None.
Background: Body weight and body mass index (BMI) are positively related to risk of colon cancer in men, whereas weak or no associations exist in women. This discrepancy may be related to differences in fat distribution between sexes or to the use of hormone replacement therapy (HRT) in women. Methods: We used multivariable adjusted Cox proportional hazards models to examine the association betwee
Abstract The aim of the thesis has been to explore representations of gender, ethnicity and generation in school readers used in the Swedish compulsory school since 1962, to find which ’discourses’, linked to equal opportunities, integration/diversity and childhood, underlie these constructions, and in which ways they may have contributed to the (re)production of different gendered, ethnified and
Background: The social environment in which children grow up is closely associated with their health. The aim of this study was to investigate the relationship between maternal educational level, parental preventive behavior, parental risk behavior, social support, and use of medical care in small children in Malmo, Sweden. We also wanted to investigate whether potential differences in child medic
Overwash is the flow of water and sediment over the crest of a beach system when the runup level of waves or the water level, often enhanced by storm surge, exceeds the local beach or dune crest height. The impacts of overwash on coastal barriers or low lying mainland coasts are striking. Overwash may cause deposition of sand on and landward of the beach crest, large fan shaped deposits on back ba
Popular Abstract in Swedish Det diagnostiska värdet av röntgen- och nuklearmedicinska undersökningar kan knappast över¬skattas. Däremot innebär undersökningar som baseras på joniserande strålning en liten risk för patienten att senare i livet utveckla en cancer. Därför är det vår skyldighet att hålla stråldoserna så låga som möjligt med bibehållen diagnostisk noggrannhet. Idag utgör medicinska undThe significant increase in the use of CT, alone or combined with SPECT or PET, has raised concerns about patient radiation exposure and the consequent increased risk of malignancy later in life. The overall objective of this work was to evaluate and optimise different approaches for minimising patient radiation absorbed dose and maintaining or improving image quality in CT, SPECT/CT, and PET/CT.
During the Salvadoran armed conflict (1980-1992) hundreds of children became separated from their families. The majority of the children were abducted by the armed forces of the government and still to this day the fate and whereabouts of most children are unknown. These children are the ''disappeared children of El Salvador''. In 1994, families of the disappeared children formed a
Abstract Purpose: The main purpose with this thesis was to describe the complexities involved when public sector organizations initiate changes in their organizational culture. This research also aims to depict how managers in a public organization interpret the implementation of two separate “shared value systems”, that originates from different parts of the organization. Research design: This th
Abstract Failures in achieving the 2010 goals of slowing down or halting the loss of biodiversity, and the setting of new biodiversity targets set for 2020, stress an urgent need to expand current reserve networks and to improve their effectiveness in protecting species and habitats. Habitat suitability models, and derived maps from them, are among the broadest used tools for identifying the ecol
Today there is a high focus on the energy use when constructing new buildings. This mainly depends on the increased regulations and energy classifications that have been issued. Because of this, studies have shown that mechanical cooling in office environments leads to high energy consumption and service costs. This has led to an increased interest in analyzing if cooling only through ventilation
Background: Circulating tumor cells (CTCs) carry independent prognostic information in patients with metastatic breast cancer (MBC) on different lines of therapy. Moreover, CTC clusters are suggested to add prognostic information to CTC enumeration alone but their significance is unknown in patients with newly diagnosed MBC. We aimed to evaluate whether longitudinal enumeration of circulating tumo
The aim of this thesis was to investigate the interactions between the kallikrein-kinin system (KKS) and the complement system during vascular inflammation and the contribution of extracellular vesicles (EVs). Vasculitis, in patients and in experimental models, was studied as a prototype inflammatory disease of the vasculature.Papers I and II addressed the impact KKS signalling has on complement a
BACKGROUND: Numerous studies report that education and exercise interventions can shift people's willingness to undergo joint replacement surgery for osteoarthritis. We aimed to investigate whether becoming unwilling to undergo surgery following an education and exercise intervention for hip and knee osteoarthritis is associated with lower probability of receiving actual surgery.METHODS AND FINDIN
Objective To date, the major pathways contributing to cardiovascular disease among night shift workers remain poorly understood. MicroRNAs (miRNAs) have been identified as novel regulators of cardiovascular risk factors and are estimated to control more than 30 candidate miRNAs among night shift workers.Materials and Methods RNA was extracted from plasma samples of 110 night and 90day shift worker
Aim: This study investigated how human activities and local environmental variables shape tree assemblages (species composition in a defined location), comparing their effects on edible and inedible tree species. Three hypotheses were tested: (1) Environmental filtering impacts spatial beta-diversity more than dispersal limitation; (2) human activities significantly influence regional tree beta-di
Populärvetenskaplig sammanfattning: En verksamhet eller åtgärd kan ha stor inverkan på människor, djur, växter, mark, vatten, luft, klimat, landskap och kulturmiljö. För att fatta bästa möjliga beslut om en projekt-ut-formning som tar hänsyn till konsekvenserna för olika berörda miljövärden åter-finns kravet på miljökonsekvensbeskrivning, MKB, i svensk lagstiftning. Syftet med en MKB är att identiAn activity or a measure might have a great impact on people, animals, plants, soil, water, air, climate and landscape. In order to describe the direct and indirect effects an intended activity might have an Environmental Impact Assessment (EIA) must be carried out. This demand is regulated in Swedish legislation and makes it possible to achieve as small impact on the environment as practicable. A
The accurate evaluation of shifts in vegetation phenology is essential for understanding of vegetation responses to climate change. Remote-sensing vegetation index (VI) products with multi-day scales have been widely used for phenology trend estimation. VI composites should be interpolated into a daily scale for extracting phenological metrics, which may not fully capture daily vegetation growth,
Residual stress can be introduced unintentionally into the workpiece with various magnitudes and distributions through all manufacturing processes. These stresses have a significant effect upon the performance of the final component. Understanding the residual stress imparted by machining is an essential aspect of understanding the machining process and overall part quality. Although many investig
