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Long-term ambient air pollution exposure and renal function and biomarkers of renal disease

Background: Despite accumulating evidence of an association between air pollution and renal disease, studies on the association between long-term exposure to air pollution and renal function are still contradictory. This study aimed to investigate this association in a large population with relatively low exposure and with improved estimation of renal function as well as renal injury biomarkers. M

Wearable Devices to Improve Physical Activity and Reduce Sedentary Behaviour : An Umbrella Review

BACKGROUND: Several systematic reviews (SRs), with and without meta-analyses, have investigated the use of wearable devices to improve physical activity, and there is a need for frequent and updated syntheses on the topic.OBJECTIVE: We aimed to evaluate whether using wearable devices increased physical activity and reduced sedentary behaviour in adults.METHODS: We conducted an umbrella review sear

Room Acoustic Ray-Tracing : Understanding, evaluating and expanding the toolset

Room acoustic simulations are an important tool, both for design of spaces with satisfactory acoustics and for use in virtual reality experiences. Auralization of acoustic simulations are becoming more and more important in the context of Virtual and Augmented reality (VR and AR respectively), as the technology is used more and more in healthcare, culture and research. In this work, ray tracing si

Polyphasal foreland-vergent deformation in a deep section of the 1 Ga Sveconorwegian orogen

Metamorphic belts in Precambrian shields expose deep interiors of orogens and are often challenging to interpret in tectonic terms. The Eastern Segment of the 1.1-0.9 Ga Sveconorwegian orogen is a metamorphic belt, which was metamorphosed at high-pressure granulite and upper amphibolite facies at 35-40 km depth and shows highly complex fold patterns. We use detailed structural analysis in combinat

Sinners and citizens: Bestiality and homosexuality in Sweden

This study is based on an analysis of more than 2,300 court cases concerning acts of bestiality and same-sex sexuality in rural and urban Sweden 1880–1950. Other written sources are forensic psychi- atric statements, mental hospital records, material from the Swedish Sex Reform movement, news- papers and scientific journals, and minutes of the Swedish Parliament and its subcommittees. In coope

Calreticulins- Calcium-Binding Proteins with Functional Diversity and Evolutionary Duality

Calreticulin is a multifunctional protein mainly localized in the endoplasmic reticulum in eukaryotic organisms, except yeasts. The protein comprises three distinct regions: the N-terminal N domain, the C-terminal C domain, and the central P domain, reflecting the functional diversity of calreticulin. The protein has been implicated in over 40 intra- and extracellular processes in mammalian cells,

Basic Tendencies of Adjectival Accentological Development in Contemporary Russian

The present doctoral thesis is a study of the problem of "variation" in relation to word-stress in Russian adjectives, in both their short and long forms. The stress variation in adjectival forms is investigated from various viewpoints, the main of which is the revelation of the basic processes of stress reorganisation in these groups of words and the establishment of main tendencies of adjectival

The association between diabetic nephropathy and autonomic nerve function in type 1 diabetic patients

Diabetic cardiovascular autonomic neuropathy increases the risk of deterioration in renal function and is associated with increased mortality in patients with renal failure. Type 1 diabetic patients with long diabetes duration, matched for age (38 +/- 9 years) and diabetes duration (28 +/- 8 years) were studied regarding the association between cardiovascular autonomic nerve function and different

New predictive and diagnostic biomarkers for preeclampsia

Abstract Preeclampsia is a serious pregnancy complication that affects 3-8% of all pregnancies leading to maternal- and fetal morbidity and mortality. The etiology is still not known in detail. Previous findings have shown an up regulation of the genes coding for fetal hemoglobin (HbF) in preeclamptic placentas. The cell-free HbF protein was shown to be accumulating in the vascular lumen, to induc

Risk of Venous Thromboembolism in Patients With Rheumatoid Arthritis and Association With Disease Duration and Hospitalization

Context Recent reports suggest that rheumatoid arthritis (RA) may be a risk factor for venous thromboembolism (VTE), particularly in conjunction with hospitalization. Using hospitalization data to identify RA and VTE may identify patients when they are at elevated risk for other reasons, obscuring the incompletely understood underlying association between RA and VTE and leading to inappropriate in

Comparing universal kriging and land-use regression for predicting concentrations of gaseous oxides of nitrogen (NOx) for the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air)

Background: Epidemiological studies that assess the health effects of long-term exposure to ambient air pollution are used to inform public policy. These studies rely on exposure models that use data collected from pollution monitoring sites to predict exposures at subject locations. Land-use regression (LUR) and universal kriging (UK) have been suggested as potential prediction methods. We evalua

Cross-bridge behaviour in skinned smooth muscle of the guinea-pig taenia coli at altered ionic strength

1. The effects of varied levels (25-300 mM) of ionic strength on mechanical properties and ATP hydrolysis rate of chemically skinned guinea-pig taenia coli fibres were investigated. 2. The tension development following activation by calcium (pCa 4 8), and relaxation following removal of calcium (pCa 9), were slower in 25 mm compared to 150 mm ionic strength. In fibres activated by thiophosphorylat

Retention patterns of asbestos fibres in lung tissue among asbestos cement workers

Retention patterns in lung tissue (determined by transmission electron microscopy and energy dispersive spectrometry) of chrysotile, tremolite, and crocidolite fibres were analysed in 69 dead asbestos cement workers and 96 referents. There was an accumulation of tremolite with time of employment. Among workers who died within three years of the end of exposure, the 13 with high tremolite concentra

From Pioneers to Target Group : Social Change, Ethnicity and Memory in a Lithuanian Nuclear Power Plant Community

Popular Abstract in Swedish Denna avhandling i socialantropologi ägnas åt analysen av sociala och kulturella processer i Visaginassamhället efter sovjettiden. Visaginas (tidigare Sniechkus) byggdes under sovjettiden, åren 1975-1989, som hemvist för personal vid Ignalinas kärnkraftverk och deras familjer. De flesta invånarna i staden är ryssar som kom till Litauen mellan 1975 och 1989 för att byggaThis thesis focused on an examination of human agency and strategies for responding to rapid social and economic change. Fieldwork was carried out in the community of Visaginas town that was built during the Soviet period in Lithuania. The town is situated next to the Ignalina nuclear power plant. The majority of the town's inhabitants are Russians who immigrated to Lithuania from other areas of t

Occurrence and degradation of peptidoglycan in aquatic environments

Mechanisms controlling microbial degradation of dissolved organic matter (DOM) in aquatic environments are poorly understood, although microbes are crucial to global nutrient cycling. Bacterial cell wall components may be one of the keys in understanding the presence of slowly degrading DOM in nature. We found that dominant components of bacterial cell walls (D-amino acids (D-AA), glucosamine (Glu

Neurogenesis and transplantation in stroke-damaged brain

Popular Abstract in Swedish Stroke hos unga vuxna råttor och möss utlöser neurogenes i den skadade regionen striatum samt i den intakta hippocampus, men eftersom stroke framförallt drabbar äldre individer, är det av största vikt att utröna åldrandets effekt på hjärnans mekanismer för återhämtning. Gamla och unga vuxna råttor inducerades med stroke genom transient ocklusion av mellersta hjärnartäreStroke in young adult rodents triggers neurogenesis in the damaged striatum and intact hippocampus. as stroke happens frequently in aged individuals it is of great importance to know whether aging affects brain recovery mechanisms. Aged and young adult rats were subjected to stroke by transient occlusion of the middle cerebral artery and proliferating cells were labeled by intraperitoneal administ

Basic Tendencies of Adjectival Accentological Development in Contemporary Russian

The present doctoral thesis is a study of the problem of "variation" in relation to word stress in Russian adjectives, in both their short and long forms. The stress variation in adjectival forms is investigated from various viewpoints, the main of which is the revelation of the basic processes of stress reorganisation in these groups of words and the establishment of main tendencies of adjectival

Improvement of Physical Activity by a Kiosk-based Electronic Screening and Brief Intervention in Routine Primary Health Care: Patient-Initiated Versus Staff-Referred.

BACKGROUND: Interactive behavior change technology (eg, computer programs, Internet websites, and mobile phones) may facilitate the implementation of lifestyle behavior interventions in routine primary health care. Effective, fully automated solutions not involving primary health care staff may offer low-cost support for behavior change. OBJECTIVES: We explored the effectiveness of an electronic

Impaired quality of life and sexual function in overweight and obese men: the European Male Ageing Study

Background: Few published data link overweight and obesity with measures of quality of life (QoL) including sexual health in men. Objective: To assess the association of overweight/obesity with impairment of physical and psychological QoL and sexual functions in men. Design and setting: Cross-sectional, multicentre survey of 3369 community-dwelling men aged 40-79 (mean +/- S.D., 60 +/- 11) years r