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Stress-related exhaustion is an increasingly focused phenomenon, although scientifically not yet fully conceptualised. This is perhaps partly due to the fact that the distinction between exhaustion and other already established concepts, such as depression, is not clear. This study explores whether exhaustion can be differentiated from depression and anxiety, by means of introducing the SF-36 vita

Measurements of nuclear properties of some neutron-rich asymmetric fission isotopes at an ISOL laboratory present a severe problem when a plasma ion source is used as the primary ion-source. The problem is associated with intense multi-charged symmetric fission contaminants that cannot be mass-separated from asymmetric fission products. In this work we demonstrate how this problem can be overcome

This thesis work is concerned with the efficient layout and operation of substations, i.e. those district heating (DH) system units which connect the network and internal building heating systems, such as radiator heating systems and domestic hot water distribution networks. The ambition was to make realistic investigations closely related to practical technologies within the field. The themes of

Within a course in academic writing, first-term students of English currently construct individualized study-plans detailing both what they should do during the term and when they should do it. Students calculate the average workload for all their courses, and include in their study-plans all the hours they should spend both in and outside the classroom on each course, totalling in 40-hour working

Popular Abstract in Swedish Katalytisk omvandling av enkla kolväten till mer användbara substanser m.h.a. homogena/lösliga komplex av övergångsmetaller är ett mycket viktigt ämnesområde inom metallorganisk kemi. För att förstå hur processen går till har ett stort antal modellföreningar syntetiserats genom åren där man har studerat hur kol-väte eller kol-kol bindningar kan brytas. Man bör notera atThe work presented in this thesis deals with metallacyclic late transition metal complexes, obtained by intramolecular Csp3-H activation, and the application of such compounds in catalysis. The new hemilabile P,O phosphines N-methyl-N-propionyl-2-(diphenylphosphino)benzylamine (DPPAM), o-(diphenylphosphino)benzoic acid ethyl ester (DPPES), o-(diphenylphosphino)benzoic acid methyl ether (DPPET) and

J. Lepowsky and R. L. Wilson initiated the approach to combinatorial Rogers-Ramanujan type identities via the vertex operator constructions of representations of affine Lie algebras. In this approach the first new combinatorial identities were discovered by S. Capparelli through the construction of the level 3 standard $A_2^{(2)}$-modules. We obtained several infinite series of new combinatorial i

The design and analysis of specular radar absorbing materials are investigated throughout the dissertation. Although the topic has been investigated for more than 60 years by many researchers and numerous designs have been proposed, still many technical challenges are remained unanswered. The basic questions are, e.g., the optimal thickness of a design, the possibility of utilization of unconventi

The aim of the work presented in this thesis is the improvement of xylose fermentation performance of recombinant Saccharomyces cerevisiae strains expressing XYL1 and XYL2 from Pichia stipitis, encoding xylose reductase (XR) and xylitol dehydrogenase (XDH). A recombinant strain of S. cerevisiae, fermenting both xylose and glucose to ethanol could decrease the production cost of ethanol from ligno-

Type 2 diabetes (T2D) is a complex disease with widespread physiological insults to the regulation of metabolic homeostasis, above all glycaemic regulation. The pathogenesis of T2D and its progression is broadly understood to be through a gradual decrease in peripheral insulin sensitivity, a compensatory rise in insulin secretion, and a gradual decline in beta-cell function, resulting in glycaemic

The purpose of this study was to evaluate a new automated method for the interpretation of lung perfusion scintigrams using patients from a hospital other than that where the method was developed, and then to compare the performance of the technique against that of experienced physicians. A total of 1,087 scintigrams from patients with suspected pulmonary embolism comprised the training group. The

Purpose: Multimodal imaging has not been documented for CABP4-related retinopathy. In this study, we describe optical coherence tomography (OCT) and fundus autofluorescence findings for five genetically confirmed cases. Methods: Retrospective case series. Results: Four patients with the previously described homozygous Saudi CABP4 founder mutation c.81_82insA (p.Pro28ThrfsX44) and one patient with

Almost half of all lower leg amputations are performed in patients with diabetes. In over 70 per cent of these cases, amputation is precipitated by progression of foot ulceration to deep gangrenous infection. Most foot ulcers are preceded by trauma, usually due to ill-fitting shoes, and are precipitated by sensory motor neuropathy with varying degrees of peripheral vascular disease. The Swedish Me

In the near future, the number of connected mobile devices and data-rates are expected to dramatically increase. Demands exceed the capability of the currently deployed (4G) wireless communication systems. Development of 5G systems is aiming for higher data-rates, better coverage, backward compatibility, and conforming with “green communication” to lower energy consumption. Massive Multiple-Input

Reality isn’t what it appears to be. Contexts are not always clear and visible. People don’t always say what they really mean. And they don’t always mean what they say. When life is your stage manager, anything can happen. I often say, life is hard, my head is harder. Making documentaries is not for the faint-hearted.This PhD project explores creative processes and parallel realities in documentar

Adoptive T-cell therapy (ACT) is a highly intensive immunotherapy regime that has yielded remarkable response rates and many durable responses in clinical trials in melanoma; however, 50-60% of the patients have no clinical benefit. Here, we searched for predictive biomarkers to ACT in melanoma. Whole exome-and transcriptome sequencing and neoantigen prediction were applied to pre-treatment sample

A fully automatic system for abdominal organ segmentation is presented. As a first step, an organ localization is obtained via a robust and efficient feature registration method where the center of the organ is estimated together with a region of interest surrounding the center. Then, a convolutional neural network performing voxelwise classification is applied. The convolutional neural network co

Background: Infertility affects 15%–25% of all couples during their reproductive life span. It is a significant societal and public health problem with potential psychological, social, and economic consequences. Furthermore, infertility has been linked to adverse long-term health outcomes. Despite the advanced diagnostic and therapeutic techniques available, approximately 30% of infertile couples

Background: Dominant and recessive autosomal pathogenic variants in the three major genes (COL6A1-A2-A3) encoding the extracellular matrix protein collagen VI underlie a group of myopathies ranging from early-onset severe conditions (Ullrich congenital muscular dystrophy) to milder forms maintaining independent ambulation (Bethlem myopathy). Diagnosis is based on the combination of clinical presen

Academia, as many other sectors, has faced wide-ranging disruptions due to COVID-19, with teaching and research activity conducted entirely online in many countries. Before the pandemic grounded travel, academics were often hypermobile, some traveling more than 150,000 kilometers per year for conferences, board meetings, collaborations, fieldwork,seminars, and lectures. It is no surprise then that