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Purpose The XPC gene is involved in DNA damage recognition in the nucleotide excision repair pathway (NER) We investigated the additive effects of single nucleotide polymorphisms (SNPs) in bladder-cancer patients and population controls for three XPC polymorphisms A499V (C>T) K939Q (A>C) and poly AT (PAT -/+) Experimental Design 311 bladder-cancer patients from a population-based cohort and 337 po
Study I: Thirteen patients underwent a modified Ross operation in which the free-standing pulmonary autograft was supported externally by a Dacron vascular prosthetic jacket (DVPJ). The tailor-made DVPJ prevented dilatation of the neo-aortic root significantly following a median follow-up of 47 months compared to a cohort of l3 matched patients undergoing conventional Ross operation. Study II: A
The cardiovascular risk for users of use of Swedish snus/American snuff (moist tobacco) has been debated for a long time. The present study was designed to examine the effects of water- or lipid-soluble (DMSO-soluble) snus and nicotine, the most important substance in tobacco, on the expression of vasocontractile G-protein coupled receptors (GPCR), such as endothelin ETB, serotonin 5-HT1B, and thr
Popular Abstract in Swedish Varje år insjuknar omkring 300 barn i cancer. Förbättrade behandlingsmetoder under de senaste decennierna har lett till att mer än tre av fyra barn idag faktiskt botas från sin sjukdom. Tyvärr drabbas en stor andel av de som överlever sin cancer av så kallade sena komplikationer till följd av den tuffa behandling de har utsatts för. Bland annat har man sett en livslång The etiology of childhood cancer is largely unknown. Approximately 1-10% of all childhood tumors are associated with known cancer predisposition syndromes. However, the contribution may be underestimated due to the failure to detect patients with genetic susceptibility for cancer when relying on known family pattern and anomalies. Growing evidence indicates that patients with genetic susceptibilit
Identification and isolation of cardiomyocytes from the heart, embryonic stem cells, or induced pluripotent stem cells is a challenging task and will require specific isolation techniques. Less than 30% of the cells within the murine heart are cardiomyocytes and, what is more, there are multiple sub-populations of cardiomyocytes like atrial, ventricular and conduction system cardiomyocytes. In Pap
Purpose: The purpose of this study was to describe the perceptions of auditors at different career stages on current management control and the work environment. In order to gain a deeper analysis of the auditors' perspective, the study has used previous empirical research and theories of motivation and job satisfaction. Thus, two research questions have been formulated to support the study.
Title: “Language is access to everything” - A qualitative study of SFI-teachers' experience of the transition to digitalized distance education. Authors: Rania Elwan and Fitore Mehmeti Supervisor: Karin Kullberg Assessor: Maria Bergendal Arvidsson The purpose of the study is to investigate from teachers for Swedish for immigrants (SFI) perspective how the transition to digitalized distance ed
Summariskt kan skiljeförfarandet beskrivas syfta till ett snabbt och slutligt avgörande av tvister utan insyn från utomstående. Med denna bakgrund är det av stor vikt för de involverade parterna att tvistelösningen inte efterföljs av en långdragen och offentlig process i allmän domstol. I svensk rätt finns därav ingen möjlighet att överklaga ett skiljeförfarande. Detta sätter stora krav på att skiCommercial arbitration can briefly be described as being designed to offer a quick and final conclusion to disputes without transparency for the public. With this in mind, it is of great importance that the verdict isn’t followed by long and public proceedings in court. Thus, the Swedish regulation doesn’t allow the losing party to appeal against the arbitrators’ verdict. This puts a heavy burden
Problem Definition: For several hundreds of years, mining in Bolivia has been an important part of the economy. The mining activity has a negative effect on both the environment and the health of the people. Previous studies conducted in the Lake Poopó area show elevated concentrations of heavy metals and ions harmful to people and nature. Also, previous studies indicate that the contamination fro
Background: Logistics and distribution of sold goods have traditionally been individually handled by each company in the Wanxingda Group with minimal coordination on group level. The strong relationships between the companies within the group and their close geographical proximity to each other indicate that there might exist potential for closer collaboration in this area. Furthermore, many of th
Sammanfattning: Många verksamheter använder karttjänster för att lösa problem och underlätta beslutsfattande. Allt fler upptäcker fördelarna med detta och integrerar karttjänster i verksamhetssystem. Dessa tjänster utvecklas från grundläggande karttjänster som kan ha betydande skillnader mellan sig vilket gör valet av tjänst till en viktig fråga. Eftersom karttjänsterna är olika och uppbyggda av eSummary: Many organizations use map services in their daily work to solve problems and enhance decision making processes. The number of organizations who enjoy the benefits of map services and integrate them into their system is increasing. To choose a certain map service is an important decision since the differences between them can be significant. The service is dependent on many minor componen
Eld är en av de viktigaste störningsprocesserna som påverkar den terrestra biosfären genom att forma vegetationens spridning, komposition, struktur, växtdiversitet och biokemiska cykler. Några av de mest påverkade ekosystemen är våt-torra områden, här klassificerade som savann eller Medelhavsområden. Denna påverkan kan studeras på olika sätt, antingen genom ett långvarigt och fortlöpande experimenFire is one of the most important disturbance processes affecting the terrestrial biosphere, altering the vegetation composition and distribution, structure, plant diversity and biogeochemical cycles. Some of the most influenced ecosystems are wet-dry areas, here classified as savannah or Mediterranean regions. The influence can be studied in different ways, either by long-term experiments like th
A Linear e+e- collider, either ILC or CLIC will be the next platform for high energy physics study to complement the LHC. Results discovered by LHC may need precision measurements before we can get full understanding of the physics. International collaborations are in the process to prepare both for the accelerator and for the experimental setup. Time projection chambers as the main central track
Abstract Authors: Katarina Dahlqvist, Helena Paulsson Title: Best interests of the child – An essay on the child's right to the stepparent Supervisor: Maria Bangura Arvidsson Assessor: Anders Östnäs Our work started in Föräldrabalken 6:9, 1 pcs, which says that if parents have joint custody and should one of them die the custody goes to the other parent. This reason finds its right in the core
In recent years, the office market has been changing, mainly due to the Covid-19 pandemic and technological innovation. This has impacted how office space is used and has led to an increase in the range of available real estate products. One of the decisions organizations need to make is whether to own or lease their space, which is a decision driven by several parameters. The right decision for a
Försörjning av varor och tjänster är en grundläggande del av ett fungerande samhälle, och stora delar av denna försörjning sker genom näringslivet och kritiska infrastrukturer. Hot i form av klimatförändringar och antagonistiska handlingar är centrala aspekter att beakta i utformningen av viktiga samhällsfunktioner för att kunna förebygga och hantera kriser. Under de senaste 10-15 åren har klimataThe supply of goods and services is a fundamental part of a functional society, and most of this supply is driven by businesses and critical infrastructures. In the shaping of vital societal functions, threats like climate change and antagonistic acts are central aspects to consider to prevent and manage potential crises. In the last 10-15 years, climate change adaption has become a tool for mitig
Filmdistributionen befinner sig i en ny digital verklighet. Den snabba tekniska utveckling som har ägt rum de senaste decennierna har inneburit stora utmaningar för såväl filmindustrins affärsmodell som de upphovsrättsliga bestämmelser som reglerar skyddet för filmverk och dess upphovsmän. Ett exempel på en bestämmelse vars tillämpningsområde är oklart till följd av den nya distributionen av digitFilm distribution has found itself in a new digital reality. The swift progress of technology that has taken place during the past decades has posed major challenges for both the film industry's business model and for the copyright laws that regulate the area. An example of a regulation whose scope is unclear as a result of the new distribution of digital copies is the principle of exhaustion.
Skiljeförfarandet utgör det enda alternativ till domstolsförfarande som också resulterar i en exigibel dom med rättskraft. Ett avtal om skiljeförfarande utgör ett hinder mot domstolsprövning om det åberopas inför domstol. Motsvarande prövningshinder gäller för skiljenämnd om en tvistefråga som anhängiggörs skiljenämnden faller utanför skiljeavtalets tillämpningsområde, eftersom skiljenämnden då inArbitration constitutes the only alternative to a judicial proceeding in court that also results in a legally binding judgement. An arbitration agreement also constitutes a procedural impediment if reference to it is made before the court. Corresponding procedural hindrance applies to an arbitration tribunal or to an arbitrator if the matter of dispute referred to arbitration lies outside the scop
Lithium ion batteries enable the implementation of renewable energy and electric vehicles, both of which are crucial for the transition to a sustainable society. Due to environmental, economic and political reasons, these batteries must be recycled efficiently. Most lithium ion batteries are placed on the market in electric vehicles, which are reaching end-of-life at an exponential pace, prompting
Lagen om hemlig dataavläsning trädde i kraft den 1 april 2020. Lagen innebär att brottsbekämpande myndigheter, utöver säkerhetspolisen, kan få tillgång till innehållet i den enskildes mobiltelefon och dator. Särskilt vid tvångsmedelslagstiftning är det viktigt att lagstiftaren förhåller sig till de rättsliga principer och begrepp som gäller på ett korrekt vis. Denna uppsats ämnar att kritiskt graThe Secret data interception law was implemented on 1 of April, 2020. The law allows law enforcement authorities, not just the security police, to gain access to information from an individuals' mobile phone and computer. In the case of coercive measures legislation, it is important that the legislator relates to the corresponding legal principles and concepts in a correct way. This essay in
