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Background: The repertoire of measures of walking in Rett syndrome is limited. This study aimed to determine measurement properties of a modified two-minute walk test (2MWT) and a modified Rett syndrome-specific functional mobility scale (FMS-RS) in Rett syndrome. Methods: Forty-two girls and women with Rett syndrome (median 18.4 years, range 2.4–60.9 years) were assessed for clinical severity, gr
BACKGROUND: Genomic rearrangements in cancer cells can create fusion genes that encode chimeric proteins or alter the expression of coding and non-coding RNAs. In some cancer types, fusions involving specific kinases are used as targets for therapy. Fusion genes can be detected by whole genome sequencing (WGS) and targeted fusion panels, but RNA sequencing (RNA-Seq) has the advantageous capability
Popular Abstract in Swedish Epilepsi är en allvarlig kronisk neurologisk sjukdom, som drabbar ungefär 1% av befolkningen. Sjukdomen yttrar sig genom plötsliga återkommande krampanfall, som beror på en obalans i hjärnan mellan hämmande (inhibitoriska) och stimulerande (excitatoriska) nervimpulser. När de stimulerande impulserna tar överhand leder detta till överstimulering, också kallad för hyperexEpilepsy is a severe chronic neurological disorder, affecting about 1% of the population. The disease is manifested by spontaneous recurrent seizures, caused by hypersynchronized neuronal activity due to imbalance in the brain between the inhibition and excitation. Symptoms are treated with anti-epileptic drugs, but unfortunately, 30-40% of patients respond poorly to current treatment. Therefore,
Spring phenophases such as the beginning of leaf unfolding, measured in the Irish gardens of the International Phenological Garden (IPG) network, indicate an earlier spring occurrence hence a longer growing season. However, these measurements are limited to selected species of trees at a few point locations in the southern half of the country. The aim of this study was to develop a methodology, ba
Arbetsgivaralliansen Branschkommitté Utbildning och Folkbildning Lärarförbundet och Lärarnas Riksförbunds Samverkansråd Akademikerförbunden/SULF Fackförbundet ST/Visions Samverkansråd Högskola Bransch- och löneavtal 2019-2022 1 Innehåll Författningar och förkortningar 2 § 1 Avtalets omfattning 3 § 2 Allmänna åligganden 4 § 3 Behörighet och bedömningsgrunder vid anställning 5 § 4 Anställning 7 § 5
Degrowth refers to an alternative human society which is simplistic, cooperative and opposite of current growth system which is based on overproduction and overconsumption. The current growth trend is indisputably unsustainable for the future being of the earth and its’ population. Resource depletion, land degradation and climate change have become inevitable due to growth system, overproduction a
Purpose: This investigation was designed to examine the effects of self-monitored training combined with the use of delayed auditory feedback (DAF), on the accuracy of articulation in acquired apraxia of speech (AOS). Background: The increased number of stroke survivors leads to higher societal costs when it comes to e.g., rehabilitation. Speech and language deficits post stroke can be diminished
Problemformulering: Det ställs alltmer skärpta krav på att förbättra miljö, arbetsmiljö, logistik och ekonomi inom byggproduktion och det krävs därmed att hitta nya metoder som tillmötesgår de nya kraven. Konfektionering har tagits upp som en metod som kan minska byggproduktionens miljöpåverkan och skapa en bättre arbetsmiljö. Om denna metod även kan användas för att effektivisera logistiken och mProblem: In the construction industry there are increasingly higher requirements to reduce the environmental impact and production costs as well as improve the work environment and construction logistics. To meet these new requirements, new production methods are needed. Studies have shown, ready-to-use construction materials can be used in order to improve the environmental impact and the work en
Background: There are two conceptually different surgical treatment options for patients with T1 colorectal cancer (CRC): radical surgical resection and local resection. In addition, adjuvant chemotherapy is recommended in cases with lymph node metastases. However, surgical overtreatment of early CRC is a concern and may be related to limitations in preoperative work-up as well as tumour risk clas
Background: Vasovagal syncope (VVS) is a common yet challenging condition with limited effective treatments. Elastic compression stockings (ECS) have been proposed as a potential therapy, but their real-world effectiveness remains unclear. Objectives: This study sought to compare the effectiveness of lower extremity compression with thigh-high ECS vs sham stockings for the prevention of VVS recurr
The area of VAT constitutes an area fully harmonized within the EU, and the framework for the European VAT is established in the VAT Directive and is implemented in Sweden through the Swedish VAT Act. The European VAT is a general tax on consumption with the purpose of only taxing purchases for personal consumption. However, the European VAT cover all stages of production and distribution. To achi
The global demand for fresh food has increased during the past five years and the demand is anticipated to continue growing in the future. The consumers' expectations are also getting higher and higher, which is why it is of great importance that the actors within the food industry meet these requirements to remain competitive. Fresh food is perishable goods which have a short shelf life. The
Climate change is expected to alter soil nutrient availability and microbial community functionality. Inputs of labile carbon (C) from root exudates can stimulate the decomposition of soil organic matter (SOM) in a phenomenon known as “priming”; driven by microbial demand for limiting resources. Climate-driven changes in resource availability may therefore influence soil susceptibility to priming,
Membrane fouling, particularly by soft, deformable particles, is a significant challenge in microfiltration (MF) processes, leading to reduced efficiency and increased operational costs. This thesis investigates the formation of filter cake layers by numerically simulating fluid flow through microfluidic membranes designed with random, non-overlapping cylindrical micropillar arrays. The study aims
Rapid internationalization of European higher education has resulted in a considerable increase in the number of English-medium instruction (EMI) degree programs now implemented at all levels of instruction. While this change of medium provides increased academic opportunities for all university stakeholders, the use of English by non-native speakers for teaching and learning in non-Anglosphere co
Denna avhandling undersöker den svenska befolkningens attityder i förhållande till en ekosocial agenda utifrån ett hållbart välfärdsperspektiv. Forskare har länge angripit frågor om miljö och välfärd som två separata fält. De aktuella miljö- och klimatförändringarna visar dock att dessa två fält måste förstås i samklang med varandra om vi ska kunna ställa om till ett klimatneutralt samhälle där håThis thesis explores Swedish residents’ attitudes related to an eco-social agenda from a sustainable welfare perspective. It investigates public support for general policy goals related to an eco-social agenda as well as for specific eco-social policies. The thesis also analyses the significance of the individuals’ socioeconomic characteristics, their values, and the context they are situated in r
Background: Long-term recovery following critical COVID-19 has not been sufficiently studied. Objective: The primary objective was to describe changes in functional outcome and Health-Related Quality of Life (HRQoL) between 3 and 12 months in critically ill COVID-19 survivors. The secondary objective was to investigate factors associated with good functional outcome and HRQoL at 12 months. Methods
Objective: To assess the association between achievement of prostate-specific antigen (PSA) levels ≤0.2 ng/mL (henceforth ‘ultralow’) and clinical outcomes in patients in the ‘Targeted Investigational Treatment Analysis of Novel Anti-androgen’ (TITAN) study (ClinicalTrials.gov Identifier NCT02489318) with metastatic castration-sensitive prostate cancer (mCSPC). Patients and Methods: Patients in th
Something that all Nordic countries have in common is that journalistic work, popular culture phenomena and public debates resulting in subsequent political initiatives have served as driving forces in the development of academic research on the Holocaust. It is also clear that the field is heavily politicized, imbued with moral questions and highly diversified.The memories of the Holocaust have i
Background: It is important to identify and evaluate cardiovascular risk factors at an early stage to address them accordingly. Among the younger population, the metabolic syndrome is less common than in older ages. However, each separate metabolic risk factor still has an additive effect on cardiovascular risk factor burden. Non-metabolic risk factors that occur in the younger population include
