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Drought is a natural disaster that occurs globally and can damage the environment, disrupt agricultural production and cause large economic losses. The accurate prediction of drought can effectively reduce the impacts of droughts. Deep learning methods have shown promise in drought prediction, with convolutional neural networks (CNNs) being particularly effective in handling spatial information. I
Background: Predicting future Alzheimer’s disease (AD)-related cognitive decline among individuals with subjective cognitive decline (SCD) or mild cognitive impairment (MCI) is an important task for healthcare. Structural brain imaging as measured by magnetic resonance imaging (MRI) could potentially contribute when making such predictions. It is unclear if the predictive performance of MRI can be
Field bio-remediation techniques (FBRT) can be a low cost method to avoid the removal of top layers of soil which are rich in organic matter and bio diversity. The use of native microorganisms in FBRT is preferable because non-indigenous species can transfer their genetic material to the environment with negative impacts on the local ecological equilibrium. Petroleum Produced Water (PPW) is an imp
Biological staging of individuals with Alzheimer’s disease (AD) may improve diagnostic and prognostic workup of dementia in clinical practice and the design of clinical trials. In this study, we used the Subtype and Stage Inference (SuStaIn) algorithm to establish a robust biological staging model for AD using cerebrospinal fluid (CSF) biomarkers. Our analysis involved 426 participants from BioFIN
Introduction: Resting heart rate has been distinctly related to both internalizing (high pulse) and externalizing (low pulse) disorders. We aimed to explore the associations between resting heart rate and suicidal behavior (nonfatal suicide attempt [SA] and suicide death [SD]) and evaluate if such associations exist beyond the effects of internalizing/externalizing symptomatology. Method: We used
The SARS-CoV-2 virus that led to COVID-19 is associated with significant and long-lasting neurologic symptoms in many patients, with an increased mortality risk for people with Alzheimer's disease (AD) and/or Down syndrome (DS). However, few studies have evaluated the neuropathological and inflammatory sequelae in postmortem brain tissue obtained from AD and people with DS with severe SARS-CoV-2 i
PurposeTo present baseline characteristics and to present the perioperative corneal thickness during corneal crosslinking (CXL) treatment for progressive keratoconus and to describe how the addition of sterile water (SW) efficaciously can maintain the corneal thickness. The treatment efficacy will be evaluated when the 1-year follow-up is complete.MethodsA randomised clinical study using epitheliu
Eczema is a common chronic disease that affects both children and adults, and may have an adverse impact on school performance, as it is characteristically pruri-tic, and hence may lead to poor concentration and ina-dequate sleep. The aim of this study was to elucidate the relationship between eczema and self-reported difficulties keeping up with school education. The study was based on cross-sect
The conversion of biomass to transportation fuels and value-added chemicals is a promising method to reduce the reliance on fossil fuels. Mo-based catalysts have been shown to be highly active in the hydrodeoxygenation of biomass-derived phenolic compounds. The catalyst active phase, surface species, and the effect of adding additional metals are not comprehensively understood. Here we compare the
The double nucleation mechanism of amyloid β (Aβ) peptide aggregation is retained from buffer to cerebrospinal fluid (CSF) but with reduced rate of all microscopic processes. Here, we used a bottom-up approach to identify retarding factors in CSF. We investigated the Aβ42 fibril formation as a function of time in the absence and presence of apolipoprotein A-I (ApoA-I), recombinant high-density lip
Opera Nova tar sin utgångspunkt i de rollfunktioner vi som individer väljer i olika grupper och situationer. Hur fria är vi i våra val? Tillsammans med publiken undersöker vi bilder av makt och genus på operascenen och i verkligheten. Vi undersöker härskartekniker och pratar om hur man kan bryta upp oönskade maktmönster. Vi arbetar med improvisation och leker fram operascener i olika klassiska musThe ensemble Operaimprovisatörerna investigated ways of deconstructing images of gender and power in opera and opera improvisation performance, by changing roles and using different readings, such as realism, parody and movement. I initiated the project inspired by a theoretical vantage point of post-structuralfeminism (Wilén, 2017, p. 17). The project focused on "interchange of traditional roles
Around the world today, universities are expected to play a unique role as creators of regional growth and innovation. While there appears to be a consensus that the role of universities has been expanded, critiques show that the contribution of universities to their regions is still not well defined. There have been some developments in the literature on the concept of modern universities such as
A large number of variants identified through clinical genetic testing in disease susceptibility genes are of uncertain significance (VUS). Following the recommendations of the American College of Medical Genetics and Genomics (ACMG) and Association for Molecular Pathology (AMP), the frequency in case-control datasets (PS4 criterion) can inform their interpretation. We present a novel case-control
At the turn of the twentieth century, infant- and child mortality declined rapidly in many industrializing societies. In Sweden, this decline coincided with industrialization and urbanization, as well as a period of growing social disparities in childhood mortality. The inequality in child survival was connected to a range of factors, including access to water- and sanitation, housing conditions,
Introduction: Therapeutic proteins are crucial in the treatment of a wide range of diseases. However, the proteins are sensitive to chemical degradation reactions, particularly deamidation and isomerization, which can compromise efficacy and safety. Formulation excipients, such as sugars and non-ionic surfactants, are commonly used to enhance stability, yet their effects on chemical degradation re
Co-pathology is a common feature of neurodegenerative diseases that complicates diagnosis, treatment and clinical management. However, sensitive, specific and scalable biomarkers for in vivo pathological diagnosis are not available for most neurodegenerative neuropathologies. Here we present Proteomics-based Artificial Intelligence for Dementia Diagnosis (ProtAIDe-Dx), a deep joint-learning model
This study investigated the applicability of mixture experimental design-based modeling approach to analyze insecticidal activity of thyme essential oils, particularly focusing on the synergistic interaction of their major constituents against Musca domestica. Chemical compositions of twelve commercially available thyme oils were analyzed using GC-MS, revealing their major constituents to be α-pin
In the last few years there has been an ongoing debate concerning the methods of assessing the quality of public libraries and their services. This study investigates the opinions and needs of the users at four different public libraries in Malm : the local libraries in Bellevueg rden, Limhamn, and Kirseberg, and the main library in central Malm . The purpose was to find out whether different user
The topic of this thesis is the preliminary ruling institution found in article 234 EC and especially the obligation of national courts of last instance to refer questions to the Court of Justice in paragraph three of this article. This institution is based on a co-operation between the ECJ and national courts giving each of the two types of courts their own tasks and responsibilities. More specif
