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While several scholars do not consider the anointing of (the feet of) Jesus in Bethany described in the Gospel of John to carry any messianic connotations, some claim that a royal messianic notion is behind the anointing. The hypothesis of this paper is that the anointing is indeed to be understood as messianic, but that it is insufficient to consider only one Christological motif to be in the bac
This thesis analyses how the capital structures of financial and non-financial firms affect each other and how shocks in the financial sector affect investments in non-financial firms. The thesis consists of three self-contained essays.The first essay provides new evidence on the capital structure determinants of non-financial firms and contributes to the discussion concerning the effect of a regu
The myc family of genes contains five functional members. We describe the cloning of a new member of the myc family from rat genomic and cDNA libraries, designated B-myc. A fragment of cloned B-myc was used to map the corresponding rat locus by Southern blotting of DNA prepared from rat X mouse somatic cell hybrids. B-myc mapped to rat chromosome 3. We have previously mapped the c-myc to rat chrom
PURPOSE: When central nervous system axons are injured, regeneration is partly inhibited by myelin-associated inhibitors (MAIs). Following traumatic brain injury (TBI) in the rat, pharmacological neutralisation of the MAIs Nogo-A and myelin-associated glycoprotein (MAG) resulted in improved functional outcome. In contrast, genetic or pharmacological neutralization of the MAI receptors Nogo-66 rece
Half the global soil carbon (C) is held in high-latitude systems. Climate change will expose these to warming and a shift towards plant communities with more labile C input. Labile C can also increase the rate of loss of native soil organic matter (SOM); a phenomenon termed ‘priming’. We investigated how warming (+1.1 °C over ambient using open top chambers) and litter addition (90 g m−2 yr−1) tre
Provupparbetning är ett viktigt steg i många metoder för kemisk analys.Detta gäller framförallt fasta prover då de kemiska ämnena som avses för analys, även kallade analyter, måste extraheras ut. Det vill säga att genomföra en överföring av analyter från provet till ett lösningsmedel. Därefter kan halten bestämmas med de metoder som ofta finns till hands i ett analyslaboratorium. I de fall då fettSupercritical fluid extraction is an extraction technique suitable for lipophilic compounds from solid samples. Most commonly supercritical carbon dioxide is the main component in the extraction phase, rendering the technique relatively environmentally benign. The extraction technique is rapid due to the low viscosity and the high diffusivity of analytes in the supercritical extraction phase.The s
Objective: To investigate the association between occupation and risk for sick leave or disability pension due to knee or hip osteoarthritis (OA) from a sex perspective. Methods: We conducted a population-based study including residents ages 40–70 years in the Skåne region, Sweden (2007) and working in the included job sectors (n = 165,179). We retrieved data on cause-specific sick leave and disab
In 1990 Venezuela started its Program for the Promotion of Researchers (PPI), in order to foster research in science and technology A partial evaluation of the effects of the program on scientific and technological activities can be carried out using data from the System for :the Promotion of Researchers Foundation Fund (SPI). A complete and definitive evaluation is not possible, due to the fact t
Contaminated sites constitute a global problem as they pollute important freshwater systems at a local scale. To effectively address these sites for remediaton, we must first characterize the sites in order to gain an understanding of the geological setting. This step is crucial as it helps determine groundwater flow pathways and the dynamics of surface water-groundwater exchange within these syst
BackgroundDiabetes and prediabetes are well-recognized risk factors for cardiovascular disease (CVD) and are marked by vascular endothelial dysfunction (ED). However, there is a scarcity of thorough population-based studies examining ED in individuals with diabetes/prediabetes free from manifest CVD. Here, we examined the association between ED assessed by reactive hyperaemia index (RHI) in the fi
Insect behaviours, such as host and mate selection, are often mediated by chemical cues. The chemical cuesare detected by large and rapidly evolving families of chemoreceptors which include odorant receptors (ORs),gustatory receptors (GRs) and ionotropic receptors (IRs). In this thesis, I used a model system of beetle(Coleoptera) species to study the functional evolution of insect ORs, their ligan
Air pollution is increasing profusely in Indian cities as well as throughout the world, and it poses a major threat to climate as well as the health of all living things. Air pollution is the reason behind degraded indoor air quality (IAQ) in urban buildings. Carbon dioxide (CO2) is the main contributor to indoor pollution as humans themselves are one of the generating sources of this pollutant. T
Three quarters of all breast cancers express the estrogen receptor (ER, ESR1 gene), which promotes tumor growth and constitutes a direct target for endocrine therapies. ESR1 mutations have been implicated in therapy resistance in metastatic breast cancer, in particular to aromatase inhibitors. ESR1 mutations promote constitutive ER activity and affect other signaling pathways, allowing cancer cell
Objective: To explore attendance at organised mammographic screening among immigrant groups that received an invitation letter and information leaflet (invitation) in their language of origin and Norwegian compared with Norwegian only. Design: Randomised controlled trial. Setting: Population based screening programme for breast cancer in Norway (BreastScreen Norway), which invites women aged 50-69
Aquaporin-0 (AQP0) is the main water channel in the mammalian lens and is involved in accommodation and maintaining lens transparency. AQP0 binds the Ca2+-sensing protein calmodulin (CaM) and this interaction is believed to gate its water permeability by closing the water-conducting pore. Here, we express recombinant and functional human AQP0 in Pichia pastoris and investigate how phosphorylation
Every person diagnosed with tuberculosis (TB) needs to initiate treatment. The World Health Organization estimated that 61% of people who developed TB in 2021 were included in a TB treatment registration system. Initial loss to follow-up (ILTFU) is the loss of persons to care between diagnosis and treatment initiation/registration. LINKEDin, a quasi-experimental study, evaluated the effect of 2 in
Cardiovascular magnetic resonance (CMR) can accurately measure left ventricular (LV) mass, and several measures related to LV wall thickness exist. We hypothesized that prognosis can be used to select an optimal measure of wall thickness for characterizing LV hypertrophy. Subjects having undergone CMR were studied (cardiac patients, n = 2543; healthy volunteers, n = 100). A new measure, global wal
The emergence of antibiotic resistance is a global health concern. Therefore, understanding the mechanisms of its spread is crucial for implementing evidence-based strategies to tackle resistance in the context of the One Health approach. In developing countries where sanitation systems and access to clean and safe water are still major challenges, contamination may introduce bacteria and bacterio
Objective: To assess the reliability of speech data and speech-related quality indicators in the Swedish quality registry for cleft lip and palate (CLP) at 10 years of age. Design: Retrospective study. Setting: University hospitals. Participants: One hundred twenty-one 10-year-olds with unilateral or bilateral CLP. Main outcome measures: Six independent raters reassessed audio recordings for compa
Importance: Allogeneic blood or marrow transplantation (BMT) is a curative option for malignant and nonmalignant diseases of childhood. However, little is known about trends in cause-specific late mortality in this population during the past 3 decades. Objectives: To examine cause-specific late mortality among individuals who have lived 2 years or more after allogeneic BMT performed in childhood a
