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Introduction: Non-suicidal self-injury (NSSI) is often met with stigma, which can deter individuals from seeking help. While most research on NSSI stigma has focused on clinical settings, the attitudes of those most likely to receive an NSSI disclosure, such as peers, friends, and family, remain underexplored. Building on qualitative findings that positive disclosure experiences can foster support
BACKGROUND: Both hospitalised (H) and non-hospitalised (NH) individuals may have different symptoms and impairments after COVID-19. We aimed to explore symptoms, mental and physical health after initial COVID-19 for both groups of individuals and the association between physical and mental impairments in relation to self-rated health status and to identify different cluster profiles.METHODS: Parti
This study evaluates how well five Regional Climate Model (RCM) projections at resolutions from 44 km to 3 km reproduce wet and dry spells compared with observations at six locations in Scania, southern Sweden. Future changes in general and extreme wet and dry signals were also analyzed under RCP8.5 to the end of the 21st century. Convection-permitting climate models (CPMs), operating at resolutio
In this thesis an optimization of a previously performed inclusive search for beyond Standard Model Physics in same-sign di-lepton final states is performed, but tuned for a doubly-charged Higgs boson decaying to same-sign di-muons. The doubly-charged Higgs boson is a proposed fundamental particle whose existence would provide evidence for theoretical extensions of the Standard Model (SM) of parti
Background: We aimed to determine corticosteroid (CS) use in paediatric inflammatory bowel disease (PIBD, < 18 years), which remains common despite recommendations for limited use and the emergence of steroid-sparing therapies. Methods: We conducted a study of all children in Sweden diagnosed with CD (n = 2460) or UC (n = 2470) in 2006–2022. Nationwide health registers provided annual individual-l
Sedan folkmord etablerades som ett brott inom internationell rätt, för närmare åttio år sedan, har antalet moraliska och mänskliga grymheter som rättsligt och juridiskt klassificerats som folkmord varit få. Det beror inte på bristen på försök att få händelser erkända som sådana, men det har oftast skett till bristande framgång. Genom vilka grupper som omfattas av skyddet, handlingarna som förbjudsSince the inception of genocide as a crime under international law, nearly eighty years ago, the number of atrocities that have been legally and judicially designated as genocides are few. This is not for lack of effort to have tragedies classified as such, but with limited success. From the protected groups to the prohibited acts to the stringent intent requirement, genocide has acquired a veneer
Strategic lawsuits against public participation (SLAPPs) deploy litigation to suppress political rights – especially public participation rights and freedoms of expression, assembly and association. The rights of journalists, human rights defenders, civil society organisations and individuals are chilled by these cases and legal threats, which convert matters of public interest into private disput
High-pressure homogenisers (HPHs) are used for a variety of food products to create emul-sions. It is interesting both from a sustainable and economical perspective to make HPHs more energy efficient due to their high energy demand and low efficiency. Previous research has shown that drop deformation is affected by the whole HPH valve geometry, including the inlet chamber, and it is hypothesised t
Masonry reuse has gained increasing attention within sustainable construction due to the substantial use and the large environmental impact associated with construction and demolition waste. The bond between brick and mortar plays a critical role in both the structural performance of masonry and the potential for future brick reclamation. Strong brick–mortar bonds improve structural capacity but m
Passive infrared sensors are widely used for lighting and building automation because they are inexpensive and low power, but they detect motion rather than presence. A person who sits still, reads, works at a desk, or sleeps can therefore disappear from the sensor state even though the room is still occupied. This thesis investigates whether a low-cost, battery-powered, privacy-preserving presenc
The multitaper spectrogram, with arithmetic and geometric mean functions, and the ambiguity domain where evaluated on simulated data and real audio samples{. This was done} to determine if they can improve the results, of classification tasks, of the single-taper spectrogram when used as input to a convolutional neural network. The spectrogram used was differentiable to allow for the window length
I denna avhandling undersöktes exekutiva funktioner (EF) hos svenska barn och ungdomar. EF definierades som en uppsättning neurokognitiva processer som reglerar kognitiva, emotionella och beteendemässiga aktiviteter, viktiga för målinriktat handlande. EF bedömdes med hjälp av själv-, föräldra- och lärarskattningar av den första och andra upplagan av Behavior Rating Inventory of Executive Function This thesis examines executive functioning (EF) among Swedish youth. EF is defined as a set of neurocognitive processes regulating cognitive, emotional, and behavioral activities essential for goal-directed behavior. I assessed EF using the self-, parent-, and teacher-report forms from the original and second editions of the Behavior Rating Inventory of Executive Function (BRIEF and BRIEF2). A pri
The invasive oomycete pathogen Aphanomyces astaci significantly threatens native European crayfish populations, prompting investigations towards the effects of protective immunostimulation on the immune response of the vulnerable noble crayfish (Astacus astacus). Here, we evaluate the effect of three oomycete-derived immunostimulant treatments: laminarin (β-1,3-glucan found within the Ap. astaci c
Deficiency in C1 inhibitor (C1INH, SERPING1) is canonically associated with hereditary angioedema (HAE-C1INH) but not thrombosis. To determine the thrombosis risk conferred by loss of C1INH in the general population, we studied genetically-defined C1INH deficiency across 635,823 participants. Functionally deleterious germline coding variation in SERPING1 was rare (~1:10,000), indicating strong gen
BACKGROUND: Catheterization of the vein is frequently a painful procedure. Assessing venous cannulation induced pain (VCP) before surgery have been used to predict the intensity of postoperative pain and postoperative opioid consumption. The aim of this study was to investigate the intra-individual variation in venous cannulation induced pain at three consecutive time points and factors influencin
BACKGROUND: Psychiatric patients may refer to concepts neither medically accepted nor easily understood to describe their experiences when seeking medical care. These concepts may lie outside the clinician's cultural references and consequently hinder the diagnostic consultation. In the fifth version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), the clinical instrument Cult
Targeted radionuclide therapy is an emerging potent therapeutic strategy in oncology. The cell surface antigen CD44v6 is a potential pan-cancer target for radionuclide therapy. This study aimed to evaluate the therapeutic efficacy, biodistribution, dosimetry, and safety profile of AKIR001, an antibody targeting CD44v6 labeled with 177Lu. Methods: The biodistribution and preclinical dosimetry of [1
BACKGROUND AND AIM: Hepatorenal syndrome (HRS) occurs in about 20 % of patients with liver cirrhosis and ascites and is characterized by intensive renal vasoconstriction, low glomerular filtration rate but preserved tubular function and normal renal histology. The potential of terlipressin and albumin to reverse HRS after a time period of 14 days has already been shown. However, intravenous albumi
Background: Most actinide nuclides fission asymmetrically. A common explanation was that this division benefited from leading to fragments in the vicinity of the doubly magic 132Sn. It was tacitly assumed that lighter nuclides would all fission symmetrically because a similar situation could not occur there. However, a weakly asymmetric mass distribution was found for some preactinides at energies
COVID-19 convalescent plasma (CCP) obtained from recently recovered people is safe and effective against SARS-CoV-2. Currently available CCP is a “hybrid” product with antibodies from individuals who had both infection and vaccination (vaccine-boosted CCP). B-cell depleted patients are at risk of not producing antibodies after either infection or vaccination, hence conceivably among those who woul
