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Neonatal resuscitation - studies in piglets

Background and aims: “It’s best to start with air” states the current guidelines on the resuscitation of babies at birth. In a piglet model mimicking severe neonatal asphyxia and circulatory arrest, different aspects of resuscitation were investigated (studies I-III). The hypotheses were that the return of spontaneous circulation (ROSC) would occur faster with the use of oxygen (I and III) or adre

Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials.

Many patients with asthma or chronic obstructive pulmonary disease (COPD) routinely receive a combination of an inhaled bronchodilator and anti-inflammatory glucocorticosteroid, but those with severe disease often respond poorly to these classes of drug. We assessed the efficacy and safety of a novel inhaled dual phosphodiesterase 3 (PDE3) and PDE4 inhibitor, RPL554 for its ability to act as a bro

On the Reliability of Mapping Studies in Software Engineering

Background: Systematic literature reviews and systematic mapping studies are becoming increasingly common in software engineering, and hence it becomes even more important to better understand the reliability of such studies. Objective: This paper presents a study of two systematic mapping studies to evaluate the reliability of mapping studies and point out some challenges related to this type of

Ghrelin treatment reverses the reduction in weight gain and body fat in gastrectomised mice.

Background and aims: The gastric hormone ghrelin has been reported to stimulate food intake, increase weight gain, and cause obesity but its precise physiological role remains unclear. We investigated the long term effects of gastrectomy evoked ghrelin deficiency and of daily ghrelin injections on daily food intake, body weight, fat mass, lean body mass, and bone mass in mice. Methods: Ghrelin wa

From localised to delocalised electronic states in free Ar, Kr and Xe clusters

We present new results for the inner valence levels of clusters of the three inert gases Ar, Kr and Xe based on photoelectron spectroscopy studies. The inner valence levels are compared to the localised core levels and to the delocalised outer valence levels. This comparison shows a gradual change from a relatively localised behaviour for Ar inner valence 3s, over the intermediate case of Kr inner

Relationship between ZnT8Ab, the SLC30A8 gene and disease progression in children with newly diagnosed type 1 diabetes

Autoantibodies against the newly established autoantigen in type 1 diabetes, zinc transporter 8, ZnT8, are presented as two types, ZnT8RAb and ZnT8WAb. The rs13266634 variant of the SLC30A8 gene has recently been found to determine the type of ZnT8Ab. The aim of this study was to explore the impact of this genetic variant and the ZnT8Ab on the residual beta-cell function during disease progression

Characterization of major enzymes and genes involved in flavonoid and proanthocyanidin biosynthesis during fruit development in strawberry (Fragaria x ananassa)

The biosynthesis of flavonoids and proanthocyanidins was studied in cultivated strawberry (Fragaria x ananassa) by combining biochemical and molecular approaches. Chemical analyses showed that ripe strawberries accumulate high amounts of pelargonidin-derived anthocyanins, and a larger pool of 3',4'-hydroxylated proanthocyanidins. Activities and properties of major recombinant enzymes were demonstr

Shoe contact dermatitis from dimethyl fumarate: clinical manifestations, patch test results, chemical analysis, and source of exposure

Background The methyl ester form of fumaric acid named dimethyl fumarate (DMF) is an effective mould-growth inhibitor. Its irritating and sensitizing properties were demonstrated in animal models. Recently, DMF has been identified as responsible for furniture contact dermatitis in Europe. Objective To describe the clinical manifestations, patch test results, shoe chemical analysis, and source of e

Occupational exposure to NDMA and NMor in the European rubber industry

Many nitrosamines are suspected of being human carcinogens, with the highest concentrations in the environment being measured in the rubber industry. Time trends of personal exposure to N-nitrosodimethylamine (NDMA) and to N-nitrosomorpholine (NMor) during the past two decades in the German rubber industry were analysed and compared with cross-sectional studies in the same period in the Netherland

Statistical parametric mapping of functional MRI data using wavelets adapted to the cerebral cortex

Wavelet approaches have been successfully applied to the detection of brain activity in fMRI data. Spatial activation patterns have a compact representation in the wavelet domain. However, classical wavelets designed for regular Euclidean spaces are not optimal for the topologically complicated gray-matter (GM) domain where activation is expected. We hypothesized that wavelet bases that are adapte

Epihealth pek1

1 23 European Journal of Epidemiology Affiliated to the European Epidemiology Federation ISSN 0393-2990 Eur J Epidemiol DOI 10.1007/s10654-013-9787-x EpiHealth: a large population-based cohort study for investigation of gene–lifestyle interactions in the pathogenesis of common diseases Lars Lind, Sölve Elmståhl, Ebba Bergman, Martin Englund, Eva Lindberg, Karl Michaelsson, Peter M. Nilsson & Johan

https://www.epihealth.lu.se/sites/epihealth.lu.se/files/epihealth_pek1.pdf - 2026-06-22

Eur j epidemiol epihealth cohort 2013

NEW STUDY EpiHealth: a large population-based cohort study for investigation of gene–lifestyle interactions in the pathogenesis of common diseases Lars Lind • Sölve Elmståhl • Ebba Bergman • Martin Englund • Eva Lindberg • Karl Michaelsson • Peter M. Nilsson • Johan Sundström Received: 28 September 2012 / Accepted: 16 February 2013 / Published online: 24 February 2013 Springer Science+Business

https://www.epihealth.lu.se/sites/epihealth.lu.se/files/eur_j_epidemiol_epihealth_cohort_2013.pdf - 2026-06-22

David gaston

A Moving Forward With Your Back to the Future The Experiences of Three Values-Communities in New Zealand for Re-Orientation of Modernity towards a Sustainable Society ‘The Angel of History must look just so. His face is turned towards the past… The storm drives him irresistibly into the future, to which his back is turned, while the rubble-heap before him grows sky-high. That which we call progres

https://www.lumes.lu.se/sites/lumes.lu.se/files/david_gaston.pdf - 2026-06-22

Carbon Embedding of Pt Cluster Superlattices Templated by Hexagonal Boron Nitride on Ir(111)

With the goal to delevop the fabrication of a new type of Pt-nanoparticle carbon-support electrocatalyst, we investigate the carbon embedding of Pt cluster superlattices grown on the moiré of a monolayer of hexagonal boron nitride (h-BN) on Ir(111). Our combined scanning tunneling microscopy (STM) and X-ray photoelectron spectroscopy (XPS) study establishes conformal C embedding of the Pt clusters

Real-time ultrasound vs. evaluation of static images in the preoperative assessment of adnexal masses

Objective To determine if the prediction of the Malignancy of all adnexal mass using pattern recognition, i.e. subjective evaluation of gray-scale and Doppler ultrasound findings, is as accurate when based on static images as it is when based on a real-time ultrasound examination. Methods The static images of 166 non-consecutive patients with 'difficult' adnexal masses, who all underwent surgery a