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Background: Providing evidence-based interpretative comments (IC) is an integral task of clinical laboratory professionals. It may be of special relevance for coagulation testing, where pathological first-line tests could trigger more specialized tests. Our aim was to evaluate the quality of ICs provided to the physician in two samples with activated partial thromboplastin time (APTT) prolongation

Directed evolution has revolutionized protein engineering. Still, enzyme optimization by random library screening remains sluggish, in large part due to futile probing of mutations that are catalytically neutral and/or impair stability and folding. FuncLib is a novel approach which uses phylogenetic analysis and Rosetta design to rank enzyme variants with multiple mutations, on the basis of predic

The theory of evolution is one of the greatest scientific achievements in the intellectual history of humankind, yet it is still contentious within certain social groups. Despite being as robust and evidence-based as any other notable scientific theory, some people show a strong reluctance to accept it. In this study, we used the Measure of Acceptance of the Theory of Evolution (MATE) and Knowledg

Background: Even though children after tonsil surgery experience pain and other limitations in their daily lives, nursing care is transferred to parents after tonsil surgery, and they might need some kind of support. The aim of the study was to test the design of a randomized controlled trial intended to evaluate a nurse-led telephone follow-up after tonsil surgery on postoperative symptoms and qu

Context. Star clusters, composed of stars born from the same molecular cloud, serve as invaluable natural laboratories for understanding the fundamental processes governing stellar formation and evolution. Aims. This study aims to investigate correlations between the Mean Interdistance (Di), Mean Closest Interdistance (Dc) and Median Weighted Central Interdistance (Dcc) with the age of star cluste

Background: Regardless of the indisputable benefits of insulin therapy, initiating insulin for newly diagnosed type-1 children with diabetes might be intimidating for parents. This study assesses the experience, fears, barriers and adherence to insulin use among the parents of early-diagnosed children with diabetes. Methods: A cross-sectional online survey was utilized for data collection from 218

Glioblastoma (GBM) is the most aggressive form of glioma with a high rate of relapse despite intensive treatment. Tumor recurrence is tightly linked to radio-resistance, which in turn is associated with hypoxia. Here, we discovered a strong link between hypoxia and local complement signaling using publicly available bulk, single-cell, and spatially resolved transcriptomic data from patients with G

Inequalities of opportunity affect a person’s life expectancy and access to basic services and human rights through discrimination, abuse, and lack of access to justice. High levels of inequality of opportunity discourage skill accumulation, choke economic and social mobility, and, consequently, depress economic growth. Inequality also entrenches uncertainty, vulnerability, and insecurity; undermi

Background: Among non-communicable disorders (NCDs), stroke remains the second leading cause of death and the third leading cause of death and disability combined (as expressed by disability-adjusted life-years lost—DALYs) in the world. Aims: The study was aimed to estimate global, regional and nationa burden of stroke and its risk factors from 1990 to 2021. Methods: Finding presented in this pape

Nonlinear phenomena (NLP) are often associated with high arousal and function to grab attention and/or signal urgency in vocalizations such as distress calls. Although biomechanical models and in vivo/ex vivo experiments suggest that their occurrence reflects the destabilization of vocal fold vibration under intense subglottal pressure and muscle tension, comprehensive descriptions of the dynamics

The Andes mountains extend north–south in a latitudinal gradient of 8500 km. Because of the great climatic variety and the peculiar north–south orographic distribution, lakes are highly diverse, including different lake origins and contrasting morphometries. We reviewed >700 ecological studies on Andean lakes to identify the main threats to these freshwater systems. The most important threats are

Food waste is currently a significant problem in today’s society where up to one third of all produced food is wasted before being consumed. The wastage occurs throughout the whole food supply chain but the largest contribution is generated in the households.Food waste is a problem which results in negative effects on the economy, the society as well as the environment. There are a myriad of facto

This thesis concerns the Swedish housing market, which is under constant debate. Prices keep increasing and many believe that this trend will consist due to low interest rates, high demand and lack of attractive building land. This tendency, resulting in a housing shortage, is particularly evident in the metropolitan areas. Earlier research states that the well-known Tobin’s q theory has a short

This bachelor thesis deals with the reporting around the demonstration in Gothenburg on September 30th 2017 arranged by Nordiska Motståndsrörelsen (NMR), a Nordic Neo-Nazi movement. After a cultural debate in Sweden regarding freedom of speech and the attendance of the internet based right-winged alternative media Fria Tider on Mässan Bok & Bibliotek, also known as Bokmässan, always arranged a

Underwater soundscapes provide valuable information for the survival of fishes. These auditory cues create “acoustic daylight” to help guide orientation to coastal areas for settlement and govern movements and between habitats in post-settlement recruits. In the temperate French Mediterranean Sea, acoustic recordings in addition to Underwater Visual Census (UVC) of the white seabream (Diplodus sar