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BACKGROUND: A multifunctional diet (MFD) combining foods and ingredients with proven functional properties, such as fatty fish and fiber-rich foods, among others, was developed and shown to markedly reduce cardiometabolic risk-associated factors.OBJECTIVE: Here, we aim at examining metabolic physiological changes associated with these improvements.METHODS: Adult overweight individuals without othe

Co-occurrence of humans and wildlife leads to interactions with potential positive or negative outcomes for the human actors and for the wild animals. It may also lead to positive or negative interactions between various human actors, who perceive the wildlife or wildlife conservation and management similarly or in different ways. The description of negative interactions as Human Wildlife Conflict

Currently studies aiming for the comprehensive metabolomics profiling of measured total fat (%) as well as fat distribution in both sexes are lacking. In this work, bioimpedance analysis was applied to measure total fat (%) and fat distribution (trunk to leg ratio). Liquid chromatography-mass spectrometry-based untargeted metabolomics was employed to profile the metabolic signatures of total fat (

Background: To maintain a low incidence of Catheter Related Infections (CRI) and Catheter Related Bloodstream Infections (CRBSI), continuous follow-up studies on catheter management are necessary. The aims of the present study were to investigate the incidence of catheter tip colonisation, CRI and CRBSI in the Region, to further explore the feasibility of automatic data collection and to investiga

Metallic nano-antennas are devices used to concentrate the energy in light into regions that are much smaller than the wavelength. These structures are currently used to develop new measurement and printing techniques, such as optical microscopy with sub-wavelength resolution, and high-resolution lithography. Here, we analyze and design a nano-antenna in a two-dimensional setting with the source b

Objective: To assess the quality of maternal and newborn care (QMNC) in countries of the former Yugoslavia. Method: Women giving birth in a facility in Slovenia, Croatia, Serbia, and Bosnia-Herzegovina between March 1, 2020 and July 1, 2021 answered an online questionnaire including 40 WHO standards-based quality measures. Results: A total of 4817 women were included in the analysis. Significant d

Background: Previous research suggests that interactions between preschool teachers and children in early care and educational contexts can contribute to the child’s positive attachment development and socioemotional adjustment. Objective: Investigate how the transition process to preschool is organized and whether various ways of organizing it may differently influence family–teacher relationship

Aromatic residues form a significant part of the protein core, where they make tight interactions with multiple surrounding side chains. Despite the dense packing of internal side chains, the aromatic rings of phenylalanine and tyrosine residues undergo 180° rotations, or flips, which are mediated by transient and large-scale “breathing” motions that generate sufficient void volume around the arom

Adjectives that are used to describe sensory experiences are often used to express more than one modality. The adjective sweet, for instance, may primarily be associated with taste (i.e., taste is the dominant modality of sweet), but it can also be used for smell, sound or sight, and possibly even for touch. It has also been shown that some sensory modalities combine more easily than others. Many

Purpose: The purpose of the present study was to investigate the ability of commercial patient quality assurance (QA) systems to detect linear accelerator-related errors. Methods: Four measuring systems (Delta 4®, OCTAVIUS®, COMPASS, and Epiqa™) designed for patient specific quality assurance for rotational radiation therapy were compared by measuring four clinical rotational intensity modulated r

We construct a coarse-grained, structure-based, low-resolution, 6-bead flexible model of bovine serum albumin (BSA, PDB: 4F5S), which is a popular example of a globular protein in biophysical research. The model is obtained via direct Boltzmann inversion using all-atom simulations of a single molecule, and its particular form is selected from a large pool of 6-bead coarse-grained models using two

Over the past three decades, numbers, particularly those that can be expressed in financial terms, have come to be presented as a form of truth. Today, numbers guide and govern us, and shape and influence who we are, or who we should try to become (Kurunmäki et al., 2016). A few decades ago, this quantifying movement was restricted to a few fields. Today, however, it appears as if no one can escap

Context: Whether patients with Cushing disease (CD) in remission have increased mortality is still debatable.Objective: To study overall and disease-specific mortality and predictive factors in an unselected nationwide cohort of patients with CD.Design, patients, and methods: A retrospective study of patients diagnosed with CD, identified in the Swedish National Patient Registry between 1987 and 2

Purpose: Habitat loss is a significant cause of biodiversity loss, but while its importance is widely recognized, there is no generally accepted method on how to include impacts on biodiversity from land use and land use changes in cycle assessment (LCA), and existing methods are suffering from data gaps. This paper proposes a methodology for assessing the impact of land use on biodiversity using

Background: Eukaryotic elongation factor 2 kinase (eukaryotic elongation factor 2 kinase, eEF2K) is a calcium calmodulin dependent protein kinase that keeps the highest energy consuming cellular process of protein synthesis under check through negative regulation. eEF2K pauses global protein synthesis rates at the translational elongation step by phosphorylating its only kown substrate elongation