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Parsing Glomerular and Tubular Structure Variability in High-Throughput Kidney Organoid Culture

High variability in stem cell research is a well-known limiting phenomenon, with technical variation across experiments and laboratories often surpassing variation caused by genotypic effects of induced pluripotent stem cell (iPSC) lines. Evaluation of kidney organoid protocols and culture conditions across laboratories remains scarce in the literature. We used the original air-medium interface pr

Structure and morphology of vesicular dispersions based on novel glycophospholipids with various monosaccharide head groups

Glycophospholipids combine the structural versatility of phospholipids and carbohydrates, but their potential as excipients and performance in other related applications remains largely unexplored due to their low natural abundance. We have synthesized four novel phosphatidyl saccharide conjugates with different carbohydrate head groups; glucose, galactose, fructose and xylose by using a Phospholi

Att vara förälder eller att utföra föräldraskap - en sociologisk undersökning av föräldraskapets acceleration

Att vara förälder innebär många olika saker. Föräldrar har såväl praktiskt som känslomässigt och moraliskt ansvar för sina barn, och inom ramen för allt detta är det mycket som behöver göras och många beslut som löpande behöver fattas. I både nyligen publicerade studier och media har det på den senaste tiden gått att läsa om utbredningen av det som kallas för intensivt föräldraskap och hur det tarThe widespread prevalence of a general intensification of parenting ideals has been described in academic research and discussed in contemporary media debates. This study constitutes a social phenomenological investigation of experiences and perceptions of parenting among the Swedish middle class, with norms, expectations, and ideals of intensive parenting as its primary focus. Semi-structured lif

När världen rubbas: Oförutsebara yttre händelser och byggkontraktet - En översiktsstudie över prisändringsvillkorets tillämpningsområde i AB 04

Som en följd av Rysslands angreppskrig på Ukraina har flertalet situationer uppstått, där entreprenörer suttit fast i avtal med utländska underleverantö-rer som tvingats höja sina priser med anledning av bland annat politiska sanktioner. Detta har föranlett att det så kallade prisändringsvillkoret i AB 04, 6.3§, blivit alltmer aktuellt. Villkoret stipulerar en rätt för entreprenö-ren att vid oföru

Vad ska en polis tåla?

Uppsatsen behandlar brottet förolämpning mot tjänsteman och hur bestäm-melsen tillämpas i praktiken när målsäganden är polis. Syftet är att analysera vilka omständigheter som tillmäts betydelse vid bedömningen av straffbarhet samt var gränsen dras mellan straffbara och icke straffbara uttalanden. Arbetet är genomfört med rättsdogmatisk metod och bygger på lagtext, för-arbeten, rättspraxis och releThis thesis examines the offence of insult against a public official and how the provision is applied in practice when the injured party is a police officer. The purpose is to analyse which factors are given weight in the assessment of criminal liability and where the boundary is drawn between punishable and non-punishable statements. The study is conducted using a legal dogmatic method and is bas

”Hur i helvete kan ni komma och kalla oss porrblad?”: Pornografiska inslag och abjekt kroppslighet i undergroundtidskriften PUSS

The satirical underground magazine PUSS, published in twenty four regular numbers in the Swedish language between 1968 and 1973, used provocative images and texts to get its critique and commentary across. This included pornographically coded images depicting nude bodies and genitalia, which in the third issue came in the form of manipulated photographs of nude or semi-nude political leaders. Thes

Radiographer's Experience of Encountering Children Suspected of Being Abused

Introduction: Child abuse is a global public health problem. It poses a threat to both physical and psychosocial well-being, resulting in serious consequences for the child, the family, and society. Radiographers are in a unique position to identify children at risk. In clinical practice, they may observe unusual interactions between children and their caregivers during radiographic procedures or

Winter fleshy-fruited plants are the catalysts for spring populations of an invasive fruit fly

Winter is a critical bottleneck period for many insects and is particularly pivotal for pest species, being a major regulator of their populations. In winter, insect fruit pests such as the invasive fly, Drosophila suzukii, not only have to cope with harsh environmental conditions but also need to find alternative resources when cultivated fruit are scarce. This study aimed to disentangle the rela

Identification of β-casein phenotypes (A1/A2) in the milk of the Indian Jersey crossbreed bovine using the high-resolution accurate mass spectrometer

Foodomics is an emerging probing method of phenotype investigation of the different milk proteins and their subtypes. The polymorphic nature of the β-casein (β-Cn) protein has shown fourteen different protein variants to date in bovines. The analysis of the β-Cn genetic polymorphism from the milk of the crossbred dairy animals is crucial for the quality assurance of the consumers from the various

Differential cross-section measurements of Higgs boson production in the H → τ+τ− decay channel in pp collisions at s = 13 TeV with the ATLAS detector

Differential measurements of Higgs boson production in the τ-lepton-pair decay channel are presented in the gluon fusion, vector-boson fusion (VBF), VH and tt¯H associated production modes, with particular focus on the VBF production mode. The data used to perform the measurements correspond to 140 fb−1 of proton-proton collisions collected by the ATLAS experiment at the LHC. Two methods are used

Effect of intravenous iron therapy on exercise performance, fatigue scores and mood states in iron-deficient recreationally active females of reproductive age : a double-blind, randomised control trial (IRONWOMAN Trial)

OBJECTIVES: Non-anaemic iron deficiency (IDNA) is highly prevalent in exercising females. Although iron therapy can be used to correct this issue, its impact on exercise performance is equivocal. Our aim was to assess the efficacy of intravenous iron therapy on exercise performance, fatigue, mood states, and quality of life in recreationally active IDNA females of reproductive age.METHODS: Twenty-

MYTH 4 : The more, the merrier – the road to freedom and well-being is paved with endless choices

This chapter challenges the widely held belief that more consumer choices lead to better outcomes. This chapter explores how the proliferation of options, while seemingly empowering, can actually lead to decision paralysis, dissatisfaction and unsustainable consumption patterns. The myth is rooted in classical economic theories that equate more choice with freedom and personal satisfaction, but ps

ECG-Based Long-Term Prediction of Atrial Fibrillation

Identification of patients at risk to develop atrial fibrillation (AF) can enable more frequent follow-up and lead to earlier detection of AF. The aim of this project was to perform long-term AF prediction based on a novel set of ECG-derived features describing the characteristics of supraventricular arrhythmias present before new onset AF. In total, 12 199 patients aged 75/76 performed repeated s

Assessment of experience, fears, barriers and adherence to insulin injection among the parents of early-diagnosed children with Diabetes

Background: Regardless of the indisputable benefits of insulin therapy, initiating insulin for newly diagnosed type-1 children with diabetes might be intimidating for parents. This study assesses the experience, fears, barriers and adherence to insulin use among the parents of early-diagnosed children with diabetes. Methods: A cross-sectional online survey was utilized for data collection from 218