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Surprising results of patch testing with the baseline series in patients with photocontact allergy to ketoprofen

Objective: Photoallergic reactions due to topical ketoprofen are common. As some simultaneous contact allergies have been described in the literature, we aimed to get an overview of the pattern of reactivity towards common allergens in the baseline series in ketoprofen-photoallergic individuals. Methods: Using our database, we found 94 patients with photocontact allergy to ketoprofen diagnosed dur

Career and family : Does outsourcing household work matter?

Despite the traditionally generous family policies in Scandinavian welfare states, few new initiatives have been introduced to alleviate the pressures of paid and unpaid work over the past decades. This 'double burden' of paid and unpaid work, particularly impacting women, can impact economic, demographic, and social outcomes. It becomes heavier as societies are faced by an ageing population. More

Perceptions of eHealth and digitalization among professional anaesthesia personnel : A Swedish national study

BACKGROUND: The objective of this study was to evaluate anaesthesia care professionals' perceptions and attitudes regarding the implementation and advancement of digital solutions in perioperative care.METHODS: Anaesthesia personnel working in public Swedish institutions where anaesthesia is administered were invited to respond to an online survey regarding their attitudes towards digitalization i

Bus travel safety - a travel chain perspective

The injury risk for bus passengers is low compared to car users. However, bus passengers also run the risk of sustaining injuries as vulnerable road users: as pedestrians or cyclists to and from the bus stop. Among vulnerable road users, seniors are a particularly important group. Hitherto, injury data have mainly been based on police-reported accidents. These accidents reveal bus occupant safety,

Chromosomal Instability and Genomic Amplification in Bone and Soft Tissue Tumours

Popular Abstract in Swedish De flesta cancerformer uppvisar förvärvade kromosomavvikelser. En del enklare avvikelser har visat sig förekomma enbart i en viss tumörform och kan därför användas som diagnostiska markörer. I de flesta fall föreligger emellertid ett komplext och ospecifikt avvikelsemönster, ibland med ett mycket kraftigt ökat antal kopior av vissa DNA-sekvenser, så kallad genamplifieriAcquired genetic abnormalities are found in all types of malignant tumours and may contribute to neoplastic processes by altering protein structure or dosage. Many bone and soft tissue tumours (BSTT) are characterised by complex patterns of chromosome changes, including extensive intratumour heterogeneity and amplification of DNA sequences. The results presented in this thesis demonstrate that the

Semipermeable membrane devices in monitoring of organic pollutants in the aquatic environment

Semipermeable membrane devices (SPMDs) are passive samplers capable of concentrating hydrophobic chemicals from water, sediments, soil and air. They consist of layflat polymeric membrane such as polyethylene containing a thin film of synthetic lipid such as triolein. The transport of hydrophobic chemicals through the membrane into the lipid is governed by the process of passive diffusion. Therefor

Vascular effects of prostacyclin in cat skeletal muscle and in the traumatised rat brain

Popular Abstract in Swedish I syfte att upprätthålla en optimal miljö för alla kroppens celler har högre stående djur utvecklat blodcirkulationen genom vilken syre- och andra närings ämnen transporteras till vävnader via artärer och de mindre arteriolerna, medan slaggprodukter förs bort med venerna. Utbytet av näringsämnen och slaggprodukter mellan blod och vävnad sker genom kärlväggen i kroppens Disturbances in microvascular function may be important for tissue damage in many disease states. Prostacyclin, a substance produced by endothelial cells, is important for the maintenance of normal vascular homeostasis and is a potential drug for treatment of microvascular dysfunction, but indications and optimal dosage remains to be established. In the present thesis we evaluated the capillary fi

Moving ERP Research Forward: the Future Directions for ERP Research

This paper presents an unbalanced overview of existing Enterprise Resource Planning (ERP) research by reassessing the body of knowledge and emphasising future research directions that need to be pursued in an attempt to fill knowledge gaps and bridge the existing gap between practitioners and academia. To fulfil this objective, nine leading international IS publications covering the period of 2006

Biomarker Discovery in Cancer and Autoimmunity using an Affinity Proteomics Platform - a Tool for Personalized Medicine

Identification of novel biomarkers for early diagnosis, prognosis, and treatment decision will be instrumental for improving disease outcome for patients suffering from complex diseases, such as cancer and autoimmune disorders. Within personalized medicine, the use of circulating biomarkers will allow clinicians to tailor medical treatment based on individual characteristics of each patient, using

Transglycosylation by Glycoside Hydrolases - Production and modification of alkyl glycosides

Popular Abstract in Swedish Om vi använder allt tillgängligt fossilt bränsle kommer detta leda till att havsnivån ökar med mer än 50 m, enligt nya rön [1]. Även om detta hot ligger långt in i framtiden, finns ett flertal akuta problem kopplade till den globala uppvärminingen. FNs klimatpanel (IPCC) förutspår i sin senaste rapport en stor ökning av torka, skogsbränder, kraftiga orkaner, svält och mTo enable the transition to a green, bio-based economy, an extensive enzymatic toolbox competitive to traditional chemical procedures is needed. One strong area for enzymes is carbohydrate chemistry, due to the over-functionalized nature of carbohydrates, difficult to handle in traditional chemistry. Glycosylation can be catalyzed by four main classes of enzymes, glycosyltransferases, glycoside ph

Crime and the City: the criminal underworld in sixteenth century Peking

The presence of a criminal underworld is one of the characteristics of a metropolis. A city unplagued by an underworld, without its share of confidence tricksters and swindlers, burglars and pick-pockets, gambling dens and houses of ill-repute, would probably not be generally counted as a great city. This is certainly true today, and it was also true four hundred years ago, and even earlier. Peki

Enhanced immune response to MMP3 stimulation in microglia expressing mutant huntingtin

Huntington's Disease (HD) is an inherited neurodegenerative disease caused by a polyglutamine expansion in the huntingtin protein. The YAC128 mouse model of HD expresses the full-length human huntingtin protein with 128 CAG repeats and replicates the phenotype and neurodegeneration that occur in HD. Several studies have implicated a role for neuroinflammation in HD pathogenesis. Studies on presymp

A systematic review of studies in the contributions of the work environment to ischaemic heart disease development

BACKGROUND: There is need for an updated systematic review of associations between occupational exposures and ischaemic heart disease (IHD), using the GRADE system.METHODS: Inclusion criteria: (i) publication in English in peer-reviewed journal between 1985 and 2014, (ii) quantified relationship between occupational exposure (psychosocial, organizational, physical and other ergonomic job factors)