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Many-photon effects in time-resolved second harmonic generation from systems in optical cavities

Second harmonic generation is popular due to its numerous applications in different technologies dealing with multiple fields of science. The rapid technical advancement with the second harmonic generation demands parallel development in the theoretical understanding. With this view in mind, in our three papers, we theoretically investigated second harmonic generation from different systems in an

Study protocol for a single-blind, parallel-group, randomised, controlled non-inferiority trial of 4-day intensive versus standard cognitive behavioural therapy for adults with obsessive-compulsive disorder

Introduction Individual cognitive behavioural therapy (CBT) with exposure and response prevention is an effective treatment for obsessive-compulsive disorder (OCD). However, individual CBT is costly and time-consuming, requiring weekly therapy sessions for 3-4 months. A 4-day intensive version of CBT for OCD delivered in group format has been recently developed in Norway (Bergen 4-day treatment, B

Production of Graphene Membranes from Rice Husk Biomass Waste for Improved Desalination

Inexpensive and efficient desalination is becoming increasingly important due to dwindling freshwater resources in view of climate change and population increase. Improving desalination techniques of brackish water using graphene-based materials has the possibility to revolutionize freshwater production and treatment. At the same time, graphene matter can be cheaply mass-produced from biowaste mat

A cryptically diverse microbial community drives organic matter decomposition in forests

Despite the critical role of microorganisms in plant and fungal residue decomposition, our understanding of their full diversity remains limited. This is due largely to the rapid microbial succession during decomposition, a scarcity of studies including multiple sampling times, and the omission of a species richness index encompassing all decay stages. To address these gaps, we conducted a meta-an

Bacteraemia with gram-positive bacteria—when and how do I need to look for endocarditis?

Background: Patients with bacteraemia caused by gram-positive bacteria are at risk for infective endocarditis (IE). Because IE needs long antibiotic treatment and sometimes heart valve surgery, it is very important to identify patients with IE. Objectives: In this narrative review we present and discuss how to determine which investigations to detect IE that are needed in individual patients with

Subarctic winter warming promotes soil microbial resilience to freeze–thaw cycles and enhances the microbial carbon use efficiency

Climate change is predicted to cause milder winters and thus exacerbate soil freeze–thaw perturbations in the subarctic, recasting the environmental challenges that soil microorganisms need to endure. Historical exposure to environmental stressors can facilitate the microbial resilience to new cycles of that same stress. However, whether and how such microbial memory or stress legacy can modulate

Haematopoietic stem cell transplantation for treatment of relapsing-remitting multiple sclerosis in Sweden : An observational cohort study

Background: A growing evidence base supports the use of autologous haematopoietic stem cell transplantation (aHSCT) for treatment of relapsing-remitting multiple sclerosis (RRMS), but it has not yet been integrated into most national clinical guidelines. The objective of this study was to assess efficacy and safety when aHSCT is implemented in routine healthcare. Methods: We assessed 231 patients

Data-driven estimation of scalar quantities from planar velocity measurements by deep learning applied to temperature in thermal convection

The measurement of the transport of scalar quantities within flows is oftentimes laborious, difficult or even unfeasible. On the other hand, velocity measurement techniques are very advanced and give high-resolution, high-fidelity experimental data. Hence, we explore the capabilities of a deep learning model to predict the scalar quantity, in our case temperature, from measured velocity data. Our

Report on 4 cases with decreased recovery due to neutralizing antibodies specific for PEGylated recombinant factor VIII

Background: The immunogenicity, safety, and efficacy of recombinant factor VIII (rFVIII) have gained increasing interest after the introduction of extended half-life products with various modifications of the rFVIII molecule, such as covalent attachment of polyethylene glycol (PEG). Anti-PEG antibodies may be associated with a temporary reduction of FVIII recovery, but according to previous studie

Hypertension management in primary health care : a survey in eight regions of Sweden

Purpose: To explore hypertension management in primary healthcare (PHC). Design: Structured interviews of randomly selected PHC centres (PHCCs) from December 2019 to January 2021. Setting: Seventy-six PHCCs in eight regions of Sweden. Main outcome measures: Staffing and organization of hypertension care. Methods of measuring blood pressure (BP), laboratory tests, registration of co-morbidities and

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The aim of this study is to explore pre-service teachers’ procedural and conceptual understanding of pupils’ understanding of mean value, before and after an intervention. Participants are 66 pre-service teachers, and two teacher educators. The data consists of five video-recorded lessons and pre-service teachers’ pre- and post-test discussions. Based on variation theory, the analysis aimed to ide

Experimental Investigation of Glycerol Derivatives as Low-Concentration Additives for Diesel Fuel

The worldwide adoption of renewable energy mandates, together with the widespread utilization of biofuels has created a sharp increase in the production of biodiesel (fatty acid alkyl esters). As a consequence, the production of glycerol, the main by-product of the transesterification of fatty acids, has increased accordingly, which has led to an oversupply of that compound on the markets. Therefo

Exposure of children and adolescents from Northeastern Slovenia to per- and polyfluoroalkyl substances

Per- and polyfluoroalkyl substances (PFAS) are of high concern for the environment, wildlife, and human health due to their persistence and potential to cause adverse health effects. Despite political measures to restrict the production and distribution of PFAS and to limit the exposure of populations, PFAS can be measured at commonly high detection frequencies in human samples. Thus, this pilot s

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STOP START PAUSE is a performance created by LIMINAL performance group in close collaboration with Danish artist duo Hesselholdt & Mejlvang.The audience was met by three emissaries armed with banners, symbols, fanfares and beliefs. They had come to help us to a new beginning without the conflicts and problems of our time. And asked the question: how do we free ourselves from ingrained patterns

Surprising results of patch testing with the baseline series in patients with photocontact allergy to ketoprofen

Objective: Photoallergic reactions due to topical ketoprofen are common. As some simultaneous contact allergies have been described in the literature, we aimed to get an overview of the pattern of reactivity towards common allergens in the baseline series in ketoprofen-photoallergic individuals. Methods: Using our database, we found 94 patients with photocontact allergy to ketoprofen diagnosed dur

Career and family : Does outsourcing household work matter?

Despite the traditionally generous family policies in Scandinavian welfare states, few new initiatives have been introduced to alleviate the pressures of paid and unpaid work over the past decades. This 'double burden' of paid and unpaid work, particularly impacting women, can impact economic, demographic, and social outcomes. It becomes heavier as societies are faced by an ageing population. More

Perceptions of eHealth and digitalization among professional anaesthesia personnel : A Swedish national study

BACKGROUND: The objective of this study was to evaluate anaesthesia care professionals' perceptions and attitudes regarding the implementation and advancement of digital solutions in perioperative care.METHODS: Anaesthesia personnel working in public Swedish institutions where anaesthesia is administered were invited to respond to an online survey regarding their attitudes towards digitalization i