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Lymphocytic infiltration of different exocrine and non-exocrine epithelia is the pathological hallmark of primary Sjögren's syndrome, whereas involvement of salivary and lachrymal glands with the clinical counterpart of dry eye and dry mouth are the predominant features of the disease, together with fatigue and musculoskeletal pain. In addition, systemic manifestations, like arthritis, skin vascul
During an ethnographic fieldwork trip conducted in June 2025 in Brazil between in two cities 4000 kilometers apart, Rio de Janeiro, my hometown, and Manaus, capital of the state of Amazonas, I conducted interviews with the eldest generation of my aunts and uncles in order to continue the investigation I have been engaged in during my doctoral studies on ancestry, migration and the ever-present eff
Traumatic brain injury (TBI) is commonly associated with white matter injury, leading to persistent symptoms and long-term disability. While advanced age is linked to worse outcome post-TBI, the influence of sex remains highly controversial. The present study aimed to identify age- and sex-dependent differences in white matter pathology during the chronic phase of TBI using the central (midline) f
Populärvetenskaplig sammanfattning: Allt fler rapporter har kommit under de senaste åren som visar på att våg- och stormklimatet har förvärrats sedan 1960-talet. Detta har oroat bland andra återförsäkringsbolag som har betalat ut allt mer pengar till stormrelaterade skador de senaste åren. Andra undersökningar har visat att det nuvarande storm- och vågklimatet inte är värre än det var i början av The effects of a global climatic change on the wind climate of northwestern Europe are investigated with the aid of a regional climate model. There have up to date been few studies of how the wind climate will react to a greenhouse gas warming. Those that have been done are mostly global scale studies and centered on changes in storm activity during the winter season. I’m using data from a regiona
Abstract This paper discusses protectionism of intellectual property rights in general and the conflict between large pharmaceutical companies’ rights to patent and developing countries’ rights to cheap generic preparation in particular. The essay focuses above all on HIV/AIDS medicine. The description tries to give an image of the different interests that collide and why they collide. The differe
Objectives To describe the prevalence of comorbidities in a population referred to standardised first-line intervention (patient education and exercise) for hip and knee osteoarthritis (OA), in comparison with the general population. Furthermore, we aimed to evaluate if eventual differences were associated with socioeconomic inequalities. Design Register-based study. Setting Primary healthcare, Sw
Among nanoscale structures of different shapes and dimensions nanowires are one of the most promising because of its truly unique properties different from their bulk counterparts. The energy quantization, perfect defect-free structure, and the possibility to grow them within the miscibility gap in combination with the benefits of bottom-up design and the possibility of integration on silicon subs
Specific features of white matter microstructure can be investigated by using biophysical models to interpret relaxation-diffusion MRI brain data. Although more intricate models have the potential to reveal more details of the tissue, they also incur time-consuming parameter estimation that may converge to inaccurate solutions due to a prevalence of local minima in a degenerate fitting landscape.
OBJECTIVE: The microenvironment of colon cancer (CC) is heterogeneous including cells of myeloid lineage affecting tumor growth and metastasis. Two functional subtypes of myeloid cells have been identified; one (M1) is tumor-inhibitory and the other one (M2) is tumor-promoting. Whether the three myeloid markers EMR1, CD206 and CD86 are expressed only in the infiltrating myeloid cells or also in th
We show that computing the Tutte polynomial of a linear matroid of dimension k on kO(1) points over a field of kO(1) elements requires kΩ(k) time unless the #ETH-a counting extension of the Exponential Time Hypothesis of Impagliazzo and Paturi [CCC 1999] due to Dell et al. [ACM TALG 2014]-is false. This holds also for linear matroids that admit a representation where every point is associated to a
Background: The etiology of periodontitis remains unclear, as is the place of gingivitis in its pathophysiology. A few studies linked the colonization by oral parasites (Entamoeba gingivalis and Trichomonas tenax) to periodontal disease and its severity. The aim of the current study was to estimate the prevalence of these oral parasites among healthy individuals, and in patients with gingivitis an
ObjectiveTo report trends and characteristics of post-biopsy infections, with regard to etiology and resistance patterns, in a large unique cohort from a single-centre using the same antibiotic prophylactic regimens during a 15-year period.MethodsThis is an observational cross sectional cohort study, including all patients who underwent transrectal prostate biopsy (TR PBx) guided by ultrasound for
In order to enhance the accountability and legitimacy of public research, performance-based research funding systems have been introduced in numerous countries during the last decades. Although this development has gathered considerable interest in recent years, it is thus far not clear how performance measures shape research practices and academic subjectivity. Combining bibliometric studies and
Purpose: The term “love brand” has recently become a buzzword among marketing practitioners. Therefore, the purpose of this paper is to define this concept, its elements, and how customers express the love they feel towards their love brand(s) in order to create a shared understanding among practitioners and the academic world. Methodology: First, a literature review is used to identify related t
En betydande del av alla offentliga upphandlingar leder till upprättandet av ramavtal. Denna avtalsform anses vara att föredra vid tillfällen då den upphandlande myndigheten har svårighet att på förhand avgöra vilken volym som kommer behövas, vid vilken tidpunkt leveransen ska ske samt vid osäkerhet kring den exakta utformningen av kontraktsföremålet. 2014 godkände Europaparlamentet tre nya direkA considerable part of all public procurements leads to the establishment of a framework agreement. This form of agreement is considered to be preferable at times when the contracting authority has difficulty to determine the volume that will be needed, at which point delivery is to take place and in the case of uncertainty about the exact framing of the subject- matter of the contract. In 2014,
Även om terrorism utgör ett växande problem kan få presentera en precis och heltäckande förklaring av dess innebörd. I en internationell såväl som akademisk kontext råder oenighet om vilka handlingar som bör omfattas. I svensk straffrätt saknas likaså en definition av begreppet; istället straffbeläggs ett stort antal terroristhandlingar under skilda brottstyper. Uppsatsens syfte är att utreda vadAlthough terrorism poses a growing threat, few can present a precise and all encompassing definition of the term. Internationally, as well as academically, there is disagreement about which acts should be subjected by the term. Swedish criminal law similarly lacks a definition; instead numerous terrorist acts are criminalized under separate forms of crimes. The purpose of this essay is to investi
