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Med en förväntad fortsatt höjning av havsvattennivån och med en exploatering av kustområden, finns ett behov av att undersöka effekterna av kustöversvämning under storm i kombination av förhöjd havsnivå. Detta för att höja kunskaperna inom detta område inför framtida utmaningar, även om denna kombination ej är vanligt förekommande på den skånska östkusten för närvarande. Den här studien använder dWith an expected continuation of a sea level rise in the era of climate change and with an exploitation of our coastal areas, there is a need to examine the impact of coastal flooding during a storm event with high sea level, to increase our knowledge for the future. Even if an event with this combination is unusual for the Scanian coastline along the Baltic sea, the impact can be severe. This stu

Global biodiversity is heavily damaged by human interventions. There are multiple drivers for human-caused biodiversity loss; however, land use linked to agricultural production is the leading one. In response to this major threat, the interest in and importance of assessing the potential biodiversity impacts, particularly those related to land use, have grown significantly. Especially within fram

Betsockerprocessen är en energiintensiv process där ångdriven indunstning används för att avlägsna stora mängder vatten från den upprenade tunnsaften, som innehåller det från betorna extraherade sockret. I takt med industrins önskade fokus på energieffektivisering har membranteknologier för förkoncentrering av tunnsaften fått ett ökat intresse. Trots lovande resultat i ett begränsat antal försök åThe beet sugar process is an energy intensive process relying on steam evaporation to remove large amounts of water from the purified thin juice containing the sugar extracted from the beets. As the industry seeks greater energy efficiency, membrane technology for pre-concentration of thin juice has attracted interest. Limited trials have shown promise but fouling, sugar losses or high osmotic pre

Fåmansföretagsreglerna i 57 kap. inkomstskattelagen (1999:1229) innehåller särregler för hur ersättning till aktiva ägare i fåmansföretag ska delas upp mellan avkastning på investerat kapital och ersättning för utfört arbete. Reg-lernas primära syfte är att förhindra inkomstomvandling för att på så sätt uppnå en neutral beskattning av skattskyldiga. Utdelning och kapitalvinst upp till ett visst beThe close company rules in Chapter 57 of the Swedish Income Tax Act (1999:1229) contain special provisions on how monetary compensation to active owners in close companies is to be divided between return on invest-ed capital and remuneration for performed work. The primary purpose of these rules is to prevent income conversion, and thereby achieving neutral taxation of taxpayers. Dividends and cap

Much of the technology in advanced diesel engines, such as high injection pressures, is aimed at overcoming the short ignition delay of conventional diesel fuels to promote premixed combustion in order to reduce NOx and smoke. Previous work in a 2 l single-cylinder diesel engine with a compression ratio of 14 has demonstrated that gasoline fuel, because of its high ignition delay, is very benefici

Background Hepatic veno-occlusive disease is a leading cause of morbidity and mortality after haemopoietic stem-cell transplantation (HSCT). We aimed to assess whether defibrotide can reduce the incidence of veno-occlusive disease in this setting. Methods In our phase 3 open-label, randomised controlled trial, we enrolled patients at 28 European university hospitals or academic medical centres. El

Background Cancer is associated with an increased risk of thromboembolic diseases, but data on the association between prostate cancer and thromboembolic diseases are scarce. We investigated the risk of thromboembolic disease in men with prostate cancer who were receiving endocrine treatment, curative treatment, or surveillance. Methods We analysed data from PCBaSe Sweden, a database based on the

Mitochondrial dysfunction has been observed in skeletal muscle of people with diabetes and insulin-resistant individuals. Furthermore, inherited mutations in mitochondrial DNA can cause a rare form of diabetes. However, it is unclear whether mitochondrial dysfunction is a primary cause of the common form of diabetes. To date, common genetic variants robustly associated with type 2 diabetes (T2D) a

Deoxyribonucleoside kinases (dNKs) carry out the rate-determining step in the nucleoside salvage pathway within all domains of life where the pathway is present, and, hence, are an indication on whether or not a species/genus retains the ability to salvage deoxyribonucleosides. Here, a phylogenetic tree is constructed for the thymidine kinase 2-like dNK gene family in metazoa. Each enzyme class (d

Antibody-mediated blockade of CTLA4 has been shown to be effective in treating a select group of patients with late-stage melanoma. The precise mechanism underlying the clinical activity of CTLA4 immunotherapy is poorly understood, although recent experimental findings indicate that antibody-mediated depletion of regulatory T cells (Tregs) in the tumor microenvironment plays a key role in efficaci

Most previous genetic epidemiology studies within the field of osteoporosis have focused on the genetics of the complex trait areal bone mineral density (aBMD), not being able to differentiate genetic determinants of cortical volumetric BMD (vBMD), trabecular vBMD, and bone microstructural traits. The objective of this study was to separately identify genetic determinants of these bone traits as a

Background: Cyclophosphamide induction regimens for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis are effective in 70 to 90% of patients, but they are associated with high rates of death and adverse events. Treatment with rituximab has led to remission rates of 80 to 90% among patients with refractory ANCA-associated vasculitis and may be safer than cyclophosphamide regimens. Me

Lymphocytic infiltration of different exocrine and non-exocrine epithelia is the pathological hallmark of primary Sjögren's syndrome, whereas involvement of salivary and lachrymal glands with the clinical counterpart of dry eye and dry mouth are the predominant features of the disease, together with fatigue and musculoskeletal pain. In addition, systemic manifestations, like arthritis, skin vascul

During an ethnographic fieldwork trip conducted in June 2025 in Brazil between in two cities 4000 kilometers apart, Rio de Janeiro, my hometown, and Manaus, capital of the state of Amazonas, I conducted interviews with the eldest generation of my aunts and uncles in order to continue the investigation I have been engaged in during my doctoral studies on ancestry, migration and the ever-present eff

Traumatic brain injury (TBI) is commonly associated with white matter injury, leading to persistent symptoms and long-term disability. While advanced age is linked to worse outcome post-TBI, the influence of sex remains highly controversial. The present study aimed to identify age- and sex-dependent differences in white matter pathology during the chronic phase of TBI using the central (midline) f

Populärvetenskaplig sammanfattning: Allt fler rapporter har kommit under de senaste åren som visar på att våg- och stormklimatet har förvärrats sedan 1960-talet. Detta har oroat bland andra återförsäkringsbolag som har betalat ut allt mer pengar till stormrelaterade skador de senaste åren. Andra undersökningar har visat att det nuvarande storm- och vågklimatet inte är värre än det var i början av The effects of a global climatic change on the wind climate of northwestern Europe are investigated with the aid of a regional climate model. There have up to date been few studies of how the wind climate will react to a greenhouse gas warming. Those that have been done are mostly global scale studies and centered on changes in storm activity during the winter season. I’m using data from a regiona

Abstract This paper discusses protectionism of intellectual property rights in general and the conflict between large pharmaceutical companies’ rights to patent and developing countries’ rights to cheap generic preparation in particular. The essay focuses above all on HIV/AIDS medicine. The description tries to give an image of the different interests that collide and why they collide. The differe

Objectives To describe the prevalence of comorbidities in a population referred to standardised first-line intervention (patient education and exercise) for hip and knee osteoarthritis (OA), in comparison with the general population. Furthermore, we aimed to evaluate if eventual differences were associated with socioeconomic inequalities. Design Register-based study. Setting Primary healthcare, Sw