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Mineralogical and geochemical studies of the non-marine Permian–Triassic (P–Tr) boundary across two stratigraphically wellconstrained sections (Commando Drift Dam and Wapadsberg, Eastern Cape Province) in the southern Karoo Basin, South Africa, have been undertaken to provide further input on the cause of this mass extinction event, and so has a sedimentological and geochemical evaluation of a thi
Histamine-producing ECL cells and ghrelin-producing A-like cells are endocrine/paracrine cell populations in the acid-producing part of the rat stomach. While the A-like cells operate independently of gastrin, the ECL cells respond to gastrin with mobilization of histamine and chromogranin A (CGA)-derived peptides, such as pancreastatin. Gastrin is often assumed to be the driving force behind the
The general aim of the research programme SPEAK (Sustainable Planning andEnvironmental Assessment Knowledge, www.speakproject.se) was to generateknowledge on, and to strengthen the role of strategic environmental assessment(SEA) in planning as a measure to attain the environmental quality objectives andto promote sustainable development. The SPEAK programme had atransdisciplinary point of departur
BACKGROUND: The Nordic countries have commonalities in gender equality, economy, welfare, and health care, but differ in culture and lifestyle, which might create country-wise health differences. This study compared life expectancy, disease burden, and risk factors in the Nordic region.METHODS: Life expectancy in years and age-standardised rates of overall, cause-specific, and risk factor-specific
BACKGROUND: Summary measures of health are essential in making estimates of health status that are comparable across time and place. They can be used for assessing the performance of health systems, informing effective policy making, and monitoring the progress of nations toward achievement of sustainable development goals. The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD
Single-family houses (SFHs) constructed between 1961 and 1980 account for approximately one-third of the total energy use, 31 TWh, for space heating and domestic hot water in Swedish SFHs. These are responsible for about 40 percent of the total energy use in all buildings. There are roughly 715,000 houses from this period and they are largely homogeneous in technical terms, with low levels of ther
Background: Osteoarthritis (OA) is one of the most common causes of disability, with a burden of disease estimated to increase over time. Joint Academy, a Web-based treatment for individuals with clinically verified knee or hip OA, was developed to increase access to and facilitate implementation of evidence-based nonsurgical OA treatment in accordance with international guidelines. Objective: The
Taxation is a key activity of any state and a constant point of political struggle. The structure of taxation is continuously changing and evolving, and its size has grown dramatically during the last two hundred years. Many of the cross-national patterns we observe today are the result of centuries old conflicts and challenges, hence we need to take history into account if we want to understand c
Aims: Ventricular longitudinal function measured as basal-apical atrioventricular plane displacement (AVPD) or global longitudinal strain (GLS) is a potent predictor of mortality and could potentially be a predictor of heart failure-associated morbidity. We hypothesized that low AVPD and GLS are associated with the combined endpoint of cardiovascular mortality and heart failure-associated morbidit
BACKGROUND: Nearly a quarter of patients with locally advanced (T4 stage) or perforated colon cancer are at risk of developing peritoneal metastases, often without curative treatment options. We aimed to determine the efficacy of adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with locally advanced colon cancer.METHODS: This multicentre, open-label trial was done in nine hos
In September 2019, the third Global Climate Strike organized by the Fridays For Future (FFF) protest campaign mobilized 6000 protest events in 185 countries and brought 7.6 million participants out onto the streets. This report analyses survey data about participants from 19 cities around the world and compares it to data from an international survey conducted in 13 European cities in March 2019.
For the sense of well-being and human health, a pleasant indoor environment is essential. Today, people spend about 90 % of their time indoors, meaning that they can be significantly affected by the buildings in which they spend most of their time. Older people are bound to spend more time indoors and also as they belong to the most sensitive age group, their indoor environments as elderly homes m
China, as a huge and promising market, has always been largely exposed to and influenced by the Japanese and Korean idol industries. With various attempts trying to adopt the transnational experienced idol production within the challenging Chinese context, numerous reality television talent shows had been introduced in the past few years. After the very first boy group talent show, Idol Producer (
Cancer immunotherapies activate the immune system to overcome tumor resistance and restore the antitumor immune response, however, excessive activation of the immune system may also affect normal tissues and organs and cause immune-related adverse events (irAEs) of varying severity. Current in vitro assays used for testing and predicting of irAEs induced by immunotherapeutics are associated with s
Tropical montane cloud forests (TMCF) are unique ecosystems that are frequently surrounded by clouds which increase humidity and promote the growth of bryophytes. Several dimensions of humidity are important for the carbon dynamics of bryophytes. Climate change is therefore projected to have a large impact on them as well as on the TMCF itself. The present study aimed to investigate the effects th
Vid entreprenadarbeten kan skador uppstå på olika typer av egendom som inte tillhör själva entreprenadarbetena enligt entreprenadavtalet. Det är viktigt att en entreprenör kan överblicka vilka risker denne tar vid utförande av kontraktsarbeten, inte minst eftersom denne behöver teckna lämpliga försäkringar som täcker riskerna. Skador som drabbar entreprenörens avtalspart, dvs. beställaren, regleraIn relation to constructional work, a large variety of damages can occur on property that does not belong to the actual construction regulated in the contract between the contractor and the employer. Consequently, it constitutes a crucial matter that the contractor will be able to foresee the risks. This is important, especially considering appropriate insurances that the contractor needs to take
Enligt svensk rätt har den som utsätts för förföljelse på grund av sin faktiska eller tillskrivna sexuella läggning rätt att erhålla flyktingstatus. En svårighet med att bedöma asylsökandens sexuella läggning är att det ofta saknas bevisning. Domstolen får därför göra en trovärdighetsbedömning av asylsökandens påstående om den sexuella läggningen. Bedömningarna i dessa mål har kritiserats för att According to Swedish law, those who are persecuted because of their actual or attributed sexual orientation have the right to obtain refugee status. However, such asylum cases are often difficult to assess, as there is often no evidence. The court shall therefore make a credibility assessment of the asylum seeker’s claim about the sexual orientation. The assessments have been criticized, because o
