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Background: Climate change and increasing threats that come with it fosters a need for changing from fossil sources of energy to renewable ones. Sweden aims to have net zero greenhouse gas emissions by the year of 2045. One of the sectors that need to take part in this shift towards fossil free energy is the transport industry. Electrification of vehicles is an important part of this shift. As a r
Popular Abstract in English A handful of diseases-causing pathogenic microorganisms claim millions of lives worldwide each year, mainly due to limited diagnostic capabilities. The lack of simple, cost-effective, sensitive and rapid on-site diagnostic tools lead to delays in the diagnoses with a subsequent lag in treatment, which in turn can result in serious complications or even loss of lives. Fast and sensitive detection of pathogenic microbial cells is a highly important task in medical diagnostics, environmental analysis and evaluation of food safety. Accordingly, the idea of microorganism identification by the recognition of specific DNA sequence using electrochemical technique is one of the leading researches in the development of diagnostic devices. In other words, it should only
CONTEXT: Mutations in the low-density lipoprotein receptor-related protein 5 (LRP5) gene cause rare syndromes characterized by altered bone mineral density (BMD). More common LRP5 variants may affect osteoporosis risk in the general population.OBJECTIVE: To generate large-scale evidence on whether 2 common variants of LRP5 (Val667Met, Ala1330Val) and 1 variant of LRP6 (Ile1062Val) are associated w
Popular Abstract in English Clothing plays an important role in our lives. It serves four main functions: adornment, status, modesty and protection. Wearing popular clothing with one’s favourite decorations, contributes to a person reaching his or her mental comfort. Clothing is also a symbol of status, and was particularly so in ancient times. Moreover, it protects the human body from injury fromClothing evaporative resistance is one of the most important inputs for both the modelling and for standards dealing with thermal comfort and heat stress. It might be determined on guarded hotplates, on sweating manikins or even on human subjects. Previous studies have demonstrated that the thermal manikin is the most ideal instrument for testing clothing evaporative resistance. However, the repea
Background: There is increasing recognition of stroke as an important contributor to childhood morbidity and mortality. Current estimates of global childhood stroke burden and its temporal trends are sparse. Accurate and up-to-date estimates of childhood stroke burden are important for planning research and the resulting evidence-based strategies for stroke prevention and management. Objectives: T
Popular Abstract in Swedish Förbränningsmotor är i dagens värld den mest använda kraftkällan för fordon. Förbränningsmotorn har kontinuerligt utvecklats och förbättrats sedan Nicolaus August Ottos och Rudolf Diesels dagar, och kommer att fortsätta att utvecklas långt in i framtiden. Ingen konkurrerande teknik har ännu på allvar utmanat förbränningsmotorns ställning. Det finns en lång rad tänkbara The prime mover in the world today is the Internal Combustion (IC) engine. The development and improvement of the internal combustion engines since Nicolaus August Otto and Rudolf Diesel has continued until today and will continue long into the future. No major competitor to the IC engine has yet emerged. There is a long list of potential competitors but they still have to prove their superiority
Popular Abstract in Swedish Skeletthälsa och livsstilsbeteenden hos unga kvinnor I Sverige kommer ungefär 50 % av alla kvinnor att drabbas av en fraktur någon gång under sitt liv. Ett starkt skelett med hög mängd benmassa är det som främst bidrar till att förebygga benskörhetsfrakturer. Kvinnor har efter ungdomsåren mindre mängd benmassa än män och mängden benmassa minskar hos kvinnor snabbare i The overall aim of this prospective observational study with a salutogenic approach was to investigate bone mineral density (BMD) and BMD changes in the heel bone, in a group of healthy women, in relation to physiological factors and lifestyle behaviours over a two-year period as well as investigating the women’s view of their lifestyle behaviours. Data were collected in 1999 (T1) and 2001 (T2). H
Popular Abstract in Swedish Begreppet social rörlese är ett centralt sociologiskt begrepp. Trots det finns det en rad olika sätt att definiera detta begrepp. Avhandlingen söker svara på frågan vad begreppet social rörelse "betyder". För att svara på den frågan utgår författaren från en arbetsdefinition och en rad dimensioner av begreppet. Via en läsning av begreppets teoretiska utveckling söker föThis thesis develops the concept formation of 'social movement'. The author stresses the importance of the inherent classical understanding of the concept as defining a collective actor involved in a struggle regarding main social and cultural trends in society. The concept of social movement is treated as having been an unclear concept. The author therefore formulates a working definition that al
Popular Abstract in Swedish Konceptet fjärrvärme inbegriper central värmeproduktion från vilken värme distribueras ut till de enskilda förbrukarna via ett rörsystem. Ett grundläggande krav, med hänsyn till fjärrvärmens konkurrenskraft, är att vinsten som görs i den storskaliga värmeproduktionen, jämfört med lokal värmeproduktion, överstiger kostnaderna för värmedistributionen. DistributionskostnadThe concept of district heating (DH) involves centralised heat production where heat is distributed to consumers via a piping network. It is essential that benefits achieved from concentrated, large-scale production instead of local production in each building exceed the costs associated with heat distribution. Since the distribution cost per delivered kWh increases as the heat density of an area
Based upon earlier experimental work by our group, we have started a human immuno-gene therapy study. The goal is to study the effects of immunisation with autologous tumour cells expressing gene sequences for human interferon-gamma For more than two decades we have sought for efficient treatment against malignant gliomas. Our most successful treatment in the animal models is immuno-gene therapy w
Background The definition and role of bulky disease in young patients (ie, aged 18-60 years) with good-prognosis diffuse large-B-cell lymphoma (DLBCL), who have been treated with CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone)-like chemotherapy with or without rituximab, remain controversial. We aimed to assess the effect of maximum tumour diameter (MTD) in these patients. Meth
Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING Dokumentation om Sjukdomar i sköldkörteln (thyroidea) finns dokumenterade i litteraturen sedan nästan 3000 år tillbaka. Många miljoner människor över hela världen lider av någon typ av sköldkörtelsjukdom, t.ex. förstorad sköldkörtel (struma/goiter), elakartade -, godartade förändringar eller överaktiv körtel (hyperthyreos, Graves’ sjukBackground: Thyroid surgery is the most common endocrine surgical operation and is considered by many to be at the zenith of endocrine surgery. A good hemostasis is mandatory during a thyroid operation and many new devices have been available during the last two decades. Total thyroidectomy, (TT) is now by many surgeons considered the method of choice when treating Graves´ disease (GD) and multino
Popular Abstract in Swedish Internet har under de senaste tio åren växt från marginalföreteelse till ett populärt och mycket använt medium. Många företeelser och tjänster tar steget över till Internet och bland dessa finns även journalistik. I fokus för denna avhandling står förändringsprocesser för journalistikens villkor, ideal och normer när nyhetsjournalistiken bedrivs på?Internet studerade utDuring the last decade the Internet has become a widely used source of information for the average person and also a publishing tool for media corporations. The transition of journalism from one medium to another is one with important implications as the world wide public consumption of online news grows. This dissertation puts focus on how journalistic content changes when it's published on the W
Popular Abstract in Swedish Mineraler fås från både fast och flytande föda. De senaste årtiondena har bordsvattenkonsumtionen ökat, och vattnets kemiska innehåll har alltmer kommit i fokus. Studier visar dessutom att grönsakers mineralinnehåll har minskat, vilket ökar betydelsen av mineralintag från annat håll. Den här doktorsavhandlingen omfattar fyra olika studier. I den första studien undersökMineral elements in drinking water have been in focus for more than a decade, especially as the habit of drinking bottled water has increased, not the least among young people. Minerals in drinking water have become more important since minerals in food, especially in vegetables, have decreased substantially the last decades. This thesis includes four different studies. In the first study 20 munic
In recent years, small businesses have received much attention from policy makers and researchers, in that these businesses are considered important for economic growth and job creation. At the same time small businesses are assumed to face major problems in securing long-term external finance, which is regarded as restraining their development and growth. Small business managers are assumed to us
Measurements of the net CO2 flux between terrestrial ecosystems and the atmosphere using the eddy covariance technique have the potential to underpin our interpretation of regional CO2 source-sink patterns, CO2 flux responses to forcings, and predictions of the future terrestrial C balance. Information contained in FLUXNET eddy covariance data has multiple uses for the development and application
Popular Abstract in Swedish Människor (och andra arter) har en grundläggande förmåga att anpassa sig till och lära sig hur omgivningen är strukturerad. Ofta lär vi oss struktur indirekt, utan att direkt och avsiktligt studera strukturen ifråga. Klassiska vardagsexempel på tämligen oavsiktlig strukturinlärning är språkinlärning, utveckling av musikaliska preferenser, inlärning av sociala regler, ocPeople can become sensitive to the general structure of different parts of the environment, often without studying that general structure directly, but through being incidentally exposed to instances that conform to the structure. When such learning proceeds unintentionally and gives rise to knowledge that is difficult to verbalize it is often referred to as implicit learning. One of the most comm
