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Background Type 2 (T2) high asthma is recognised as a heterogenous entity consisting of several endotypes; however, the prevalence and distribution of the T2 biomarkers in the general asthma population, across asthma severity, and across compartments is largely unknown. The objective of the present study was to describe expression and overlaps of airway and systemic T2 biomarkers in a clinically r

We present an evaluation of a nested high-resolution Goddard Earth Observing System (GEOS)-Chem chemistry transport model simulation of tropospheric chemistry over tropical South America. The model has been constrained with two isoprene emission inventories: (1) the canopy-scale Model of Emissions of Gases and Aerosols from Nature (MEGAN) and (2) a leaf-scale algorithm coupled to the Lund-Potsdam-

Close international collaboration between pediatric oncologists has led to marked improvements in the cure of patients, seen as a long-term overall survival rate of about 80%. Despite this progress, neuroblastoma remains a challenging disease for both clinicians and researchers. Major clinical problems include lack of acceptable cure rates in high-risk neuroblastoma and potential overtreatment of

Macroporous hydrogels (MHs), cryogels, are a new type of biomaterials for tissue engineering that can be produced from any natural or synthetic polymer that forms a gel. Synthetic MHs are rendered bioactive by surface or bulk modifications with extracellular matrix components. In this study, cell response to the architecture of protein ligands, bovine type-I collagen (CG) and human fibrinogen (Fg)

Inferential models have long been used to determine pollutant dry deposition to ecosystems from measurements of air concentrations and as part of national and regional atmospheric chemistry and transport models, and yet models still suffer very large uncertainties. An inferential network of 55 sites throughout Europe for atmospheric reactive nitrogen (N-r) was established in 2007, providing ambien

Background: Chronic Pseudomonas aeruginosa (PA) infection causes increased morbidity and mortality in cystic fibrosis (CF). This study aimed to answer the following questions: Does the prevalence of chronic infection with PA differ between the CF centres in Scandinavia? Which differences exist concerning segregation and treatment of PA? Methods: 989 patients (86%) from all eight CF-centres in Scan

Large software organizations with a product line development approach face many challenges regarding testing. Test managers need to make tradeoffs along three dimensions of repeated testing (abstraction level, time and product space) and consider a range of goals and constraints. In order to keep pace with the decreased development time for new products, which is enabled by the systematic reuse, s

Background: Forensic psychiatric patients present a challenge as they manifest severe mental disorders together with criminal behaviour. There are well-known risk factors for criminal behaviour in the general population, yet knowledge of what predicts reconviction in the Swedish forensic population in the long-term perspective is still insufficient. Aims: The study aims to (1) describe background

Planeter är mycket vanliga i vår galax. De senaste 20 åren har man upptäckt att de flesta solliknande stjärnor har planeter kretsande omkring sig. Man vet också att det finns en stor variation av exoplaneter. Runt 50\% av alla solliknande stjärnor har superjordar (planeter med en massa eller radie mellan jordens och Neptunus) kretsande tätt intill sig vilket gör solsystemet otypiskt. Man har hittaOver the past 20 years we have discovered that exoplanets are common in the Galaxy, and are far more diverse than anyone expected. Half of all Sun-like stars are accompanied by at least one super-Earth (a planet with a size between Earth and Neptune), many planets have very high eccentricities indicative of a dynamical origin, and a small fraction of stars are accompanied by hot Jupiters, whose or

Purpose: To evaluate patients with central retinal vein occlusion (CRVO) and neovascular glaucoma (NVG) using electrophysiology in order to gain better understanding of visual outcome and risk factors, such as previously diagnosed primary open-angle glaucoma (POAG). Methods: Eighty-three patients (83 eyes) initially presenting with CRVO and examined with full-field electroretinography (ERG) within

Popular Abstract in Swedish Lödda kompakta plattvärmeväxlare används i stor utsträckning i kyl – och värmepumpanläggningar samt luftkonditioneringsanläggningar. Såväl enfasvärmeutbyte, dvs värmeutbyte mellan två vätskor, som fasomvandling genom kondensation och förångning är viktiga tillämpningsområden. Apparaterna användes inom industri, hushåll, samhälleliga inrättningar mm. Prestandan för olikaThis thesis work presents various performance estimation methods of compact brazed plate heat exchangers (BPHE) operating in single phase, condenser, evaporator, cascaded and transcritical applications. Such methods play a vital role in development of heat exchanger selection software and during geometry parameter estimation in the new product development process. The suitability of employing comm

I samhällsdebatten har åsikter om en mer effektiv brottsbekämpning växt fram på den senaste tiden. Debatten har utmynnat i flertalet offentliga utredningar som presenterar potentiella lagändringar. Förslagen innebär att en avvägning måste göras mellan effektiv brottsbekämpning och rättssäkerhet, eftersom dessa medför en stor risk att individens rättigheter inskränks. Syftet med uppsatsen är att bIn the public debate, opinions about more effective law enforcement have emerged in recent years. The debate has resulted in public investigations that present potential changes to the law. The proposals imply that a balance must be struck between effective law enforcement and the rule of law, as the proposals entails a great risk for the rights of the individual to be restricted. The purpose of

The High-Intensity Baryon Extraction and Measurement experiment (HIBEAM) is proposed as one of the experimental stations at the European Spallation Source (ESS). This experiment will mainly focus on the neutron into sterile neutron oscillations which violate the baryon number (B) by one unit. The sterile neutrons are hypothetical dark matter candidates. The neutrons suitable for the experiment hav

A modern automotive vehicle is a complex technical system, containing many electronic, mechanical, and software parts. Typically, a high-end vehicle contains 70 or more electronic control units (ECUs) on average. These are controlling a large number of distributed functions, of which many are safety-critical, and adding complexity, which is surpassing 100 million lines of code. Furthermore, the co

Geografiska data är all data som är knutna till ett geografiskt läge och används inom många olika områden i samhället såsom all form av samhällsbyggnad och samhällsplanering, klimat och miljö, kultur och natur, krishantering samt transporter och logistik. För att geografiska data ska kunna användas över läns- och kommungränser samt i olika organisationer krävs ett enhetligt system och standarder fGeographic data are data that is linked to a geographic location and is used in many different areas of society, such as all types of community and community planning, climate and environment, culture and nature, crisis management, transport and logistics. In order for geographic data to be used across county and municipal boundaries as well as in different organisations, a uniform system and stan

Problem - Uncertainty greatly burdens innovation in tech-driven industries which has made decision-making an art-like navigation, especially within the Fuzzy Front End of operations. This has motivated previous researchers to study the effectual decision-making principles originated by Sarasvathy in regard to a wide variety of audiences such as entrepreneurs, start-ups and top management. Employee

This study sets out to investigate the non-diegetic music in Christopher Nolan’s Interstellar (2014) in order to highlight its implicit narrative functions and meanings. The theoretical approach consists of semiotic concepts such as ‘Cognitive denotative’ and ‘Cognitive connotative’ functions by Emilio Audissino, ‘Myth’ and ‘Anchorage’ by Barthes as well as Claudia Gorbman’s ‘Connotative Cueing’.

This scientific report has mainly studied the concept of Industry 4.0 and the possibility to send data from a temperature sensor to the cloud, a process which is an example of the term Internet of Things. The study has been conducted for the consultant business Rejlers to give the CEO as well as the Technical Manager a broader view of how they could implement IoT on behalf of costumers in the futu

The Chittagong Hill Tracts (CHT) of Bangladesh was full of natural resources like water, river, forest, agriculture, land. Various agencies like government and non-government (local, national, and international) have undertaken and implemented development programs in the CHT at different times encompassing those natural resources to develop the CHT economy and contribute to the overall economic

As a social worker you often meet children that are exposed to harmful environments in one way or another. Children who grow up in these circumstances could easily be forgotten, there-fore it is vital that these children are brought to attention. In these situations it´s necessary to find which positiv measures would be benefitial for these children. The internet is an expan-sive resource due to t