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Reduction of trans-[Pt(CN)4 X2]2- (X = Cl or Br) as model compounds for antitumour-active platinum(IV) pro-drugs, to [Pt(CN)4]2- by L-methionine, MeSR, has been studied at 25 °C in the range 0 < pH < 12 (X = Cl) and 0 < pH < 6 (X = Br) by use of stopped-flow spectrophotometry. The stoichiometry is [Pt IV] : [MeSR] ≈ 1 : 1; the reaction products are methionine S-oxide and [Pt(CN)4]2- as identified
Embedded real-time systems must meet timing constraints while minimizing energy consumption. To this end, many energy optimizations are introduced for specific platforms or specific applications. These solutions are not portable, however, and when the application or the platform change, these solutions must be redesigned. Portable techniques are hard to develop due to the varying tradeoffs experie
Denna studie har syftat till att kartlägga allmänbefolkningens exponering för vissa luftburna cancerframkallande ämnen: bensen, 1,3-butadien, formaldehyd, kvävedioxid, kväveoxid samt ozon. Undersökningen genomfördes i Malmö under hösten 2014 och inkluderade totalt 42 slumpvis utvalda malmöbor i åldrarna 20-50 år. Samtliga mätningar, bortsett från formaldehyd, upprepades på 22 personer. Tjugo av de
This is a comment on Lofstedt and Bouder?s paper, which explores the prospects of evidence based uncertainty analysis in Europe, focusing on the ongoing development on uncertainty analysis at the European Food Safety Authority (EFSA). We very much welcome a discussion on the need to develop better treatment and communication of uncertainty in risk analysis, as we believe that such discussion is loThis is a comment on Lofstedt and Bouder’s paper, which explores the prospects of evidence based uncertainty analysis in Europe, focusing on the ongoing development on uncertainty analysis at the European Food Safety Authority (EFSA). We very much welcome a discussion on the need to develop better treatment and communication of uncertainty in risk analysis, as we believe that such discussion is lo
This book analyses the phenomenon of digitally mediated property and considers how it problematises the boundary between human and nonhuman actors. The book addresses the increasingly porous border between personhood and property in digitized settings and considers how the increased commodification of knowledge makes visible a rupture in the liberal concept of the property owning, free, person. En
In the context of the COVID-19 pandemic, we aim to identify and understand the obstacles and barriers in applying electronic exams successfully in the process of distance education. We followed an exploratory descriptive approach through a questionnaire (one general, open question) with a sample of university teachers and students in four of the largest universities Palestinian in Gaza. A total of
Sulbutiamine is a thiamine derivative developed in Japan in the mid-60's as a beriberi treatment drug. Since then, different potential applications have been described. For instance, there is some evidence that sulbutiamine can have anti-fatigue, nootropic, and antioxidant effects, which led to its use as a sport supplement (although some authors argue it is actually a masking doping strategy). Mo
Fear of large carnivores such as brown bears may restrict people’s outdoor activities regardless of experts’ estimated risk of attack. This research study empirically examined three exposure interventions in the form of guided walks intended to give people living in brown bear areas tools for coping with their fear. All interventions significantly reduced fear, decreased people’s perceived vulnera
MicroRNAs (miRNA) play an important role in various biological process by regulating gene expression. Their abnormal expression may lead to cancer. Therefore, analysis of such data may discover potential biological insight for cancer diagnosis. In this regard, recently many feature selection methods have been developed to identify such miRNAs. These methods have their own merits and demerits as th
Mathematical optimization is becoming increasingly important for engineering in general and control in particular. This thesis deals with numerical methods, primarily direct collocation, and symbolic methods, primarily block-triangular ordering and tearing, for numerical solution of general dynamic optimization problems involving dynamical systems modeled by large-scale differential-algebraic equa
Integration of evolutionary and developmental biology has stimulated novel insights on the origins and maintenance of phenotypic variation. For instance, phenotypic accommodation predicts that trait covariance originates via a novel developmental input caused by genetic change in one trait, but not the other. Darwin provided a striking example of this process in the ‘lop-eared’ rabbit by demonstra
Popular Abstract in Swedish INTRODUKTION Aminosyror är en grupp små molekyler som finns i våra celler. Totalt finns det tjugo olika aminosyror, vilka kan binda till varandra i långa kedjor varvid de bildar proteiner (äggviteämnen). Proteiner ansvarar för en lång rad funktioner i organismen och varje cell i en organism måste därför kunna syntetisera ett par tusen olika proteiner för att kroppen ska1-microglobulin is a small glycoprotein present in plasma and in tissues surrounding the gastrointestinal and respiratory tracts. a1-microglobulin is a member of the lipocalin protein family and exhibits several of the typical traits of a lipocalin; it binds an unknown ligand which causes the brown color of the protein, it forms complexes with various different proteins and there have been indica
Background: Tibial osteotomy is a treatment for younger and/or physically active patients suffering from uni-compartmental knee osteoarthritis. The open wedge osteotomy by the hemicallotasis technique includes the use of external fixation. The use of external fixation has several advantages, as early mobilization and the opportunity for optimal correction. However, the hemicallotasis technique has
Popular Abstract in Swedish Denna avhandling behandlar olika frågor som var och en är av stor betydelse för förståelsen av dynamiska brott i stål. Särskilt betonas sprickpropageringsförsök, utförda i överslagsområdet mellan segt och sprött beteende, samt de slutsatser som kan dras av försöken. En fråga berör den fysikaliska bakgrunden till viskoplasticitet. Det visar sig att en beskrivning av terThe thesis addresses different questions, each necessary in the understanding of dynamic fracture initiation and crack propagation in steel. Emphasis lays on dynamic crack propagation experiments performed in the ductile to brittle transition region and possible conclusions, that can be drawn from them. One question regards the physical basis for for viscoplasticity. Dislocation slip by thermal a
Most of field stars originate from dissolved star clusters. If the gas cloud is well mixed the stars in the cluster are expected to be chemically homogenous. Although the original kinematical information of a star may be lost under the Galactic dynamic evolution, the chemical signatures are preserved in the form of elemental abundances in individual low-mass stars. The present-day distribution of
Popular Abstract in Swedish Äldre personer som erhåller permanent hjälp i sitt dagliga liv har ökat i takt med att livslängden ökat. Många äldre personer kommer troligen framöver att erhålla hjälp i sitt ordinära boende, eftersom den kommunala vården och omsorgen framför allt inom särskilt boende har minskat i omfattning i förhållande till antalet äldre över 65 år. Svensk policy strävar mot att alThe aim of this thesis was to investigate self-reported diseases and complaints, quality of life (QoL), help received with activities of daily living among older people and in relation to who provided the help, and in comparison with those without ADL help. The aim was also to investigate older people’s experiences of receiving help. Data were collected using postal questionnaires in two populatio
We consider a MIMO system where error-prone feedback from the receiver is used by the transmitter to select a single optimum antenna to transmit data. Such error-prone feedback is common in the bandwidth-limited real systems, and is in marked contrast with the idealizations assumed in the selection literature. We show how the signaling assignment, which maps the antenna indices to the codewords th
ERP systems became popular with large organizations in the 1990s. In the 21st Century, these products were expanded by addition of supply chain management (SCM) and customer relationship management (CRM), as well as access through the Web, creating the ERP II concept. Efforts to increase the market led vendors to serve not only large organizations, but also focus more on small-to-medium sized ente
The objectives of this activity were to propose a number of alternative HMI solutions (visual, auditory and haptic) for the concept of Safe Speed and Safe Distance and to carry out a pre-screening procedure with a number of test persons in order to give recommendations for the alternative building elements of the SASPENCE “warning-package” consisting of the combination of these modes to be tested
The importance of using efficient bases for current expansion in numerical computations of electromagnetic field problems has been emphasized for several decades. It is well known that the basis functions should approximate the physical current (electric or magnetic) to some extent. Moreover, for efficiency, it is reasonably to require that only a few basis functions are needed in order to obtain
