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There has long been a crisis of housing affordability in London, which the government and private sector are failing to address. On top of the socio-economic challenges brought about by this, London’s current and new stock of housing are not built to the necessary environmental standards to achieve legally binding environmental targets. However, the contentious Brexit vote and the continued uncert
Den 30 juni 2022 trädde nya lagförändringar i kraft efter att förslaget om reformerad arbetsrätt antagits. En av lagförändringarna var 12 a § i lag (2012:854) om uthyrning av arbetstagare. Denna innebär att kundföretag ska erbjuda tillsvidareanställning för inhyrda arbetstagare som utfört arbete åt företaget på samma driftsenhet i sammanlagt mer än 24 månader under en 36-månaderperiod. Lagförändri
Context: Scope management is a core part of software release management and often a key factor in releasing successful software products to the market. In a market-driven case, when only a few requirements are known a priori, the risk of overscoping may increase. Objective: This paper reports on findings from a case study aimed at understanding overscoping in large-scale, market-driven software dev
Motivated by growing considerations of the scale, severity, and risks associated with human exposure to indoor particulate matter, this work reviewed existing literature to: (i) identify state-of-the-art experimental techniques used for personal exposure assessment; (ii) compare exposure levels reported for domestic/school settings in different countries (excluding exposure to environmental tobacc
Ischemic heart disease is the leading cause of death in high-income parts of the world and is caused mainly by atherosclerosis in the coronary arteries. The rupture of an atherosclerotic plaque with subsequent platelet activation and clot formation can lead to myocardial infarction (MI). Atherosclerosis is a complex process, which involves the accumulation and oxidation of low-density lipoprotein
This study evaluated the sample sizes necessary to estimate several soil and vegetation characteristics within 10% confidence intervals with 95% probability in three terra firme tropical rainforest sites. Across all three plots, the most spatially heterogeneous variables were measurements of total standing crop root mass, ground surface litter mass, litter fall, root growth and soil respiration wh
Syftet med uppsatsen är att undersöka hur Socialdemokraternas partiledare och statsminister Göran Persson och Moderaternas partiledare Bo Lundgren hanterar en debatt inför det stundande riksdagsvalet. För att uppfylla syftet analyseras valduellen ur ett retoriskt perspektiv med tre teorier. Dessa är retorisk situationsanalys för att klargöra Perssons och Lundgrens retoriska situation och hur de fö
This study investigates the potential of large language models (LLMs), such as ChatGPT, to aid venture capitalists in the screening of startups that maximize sustainability impact. To determine the scope that maximizes impact for venture capitalists' and to identify effective screening criteria, the study utilized theoretical research and interviews. The thesis suggests that the ideal investme
I detta arbete undersöker jag det allmänna ombudets roll inom socialförsäkringssystemet och hur regeringens styrning av ombudet kan tolkas. Jag undersöker även hur detta förhåller sig till några av de problemen som existerar inom socialförsäkringsrätten idag. Jag diskuterar även hur lagstiftningen kan förändras för att göra det lättare för det allmänna ombudet att lyckas med sitt uppdrag. I undersIn this thesis I examine the role of the General Representative (allmänna ombudet) in the Swedish Social Security Insurance Administration. More specifically, I examine how the role of the general representative relates to some contemporary problems that exist within the social insurance system. Further, I discuss how the legislation can be developed in order to facilitate for the general represen
In plants the chloroplast thylakoid membrane is the site of light-dependent photosynthetic reactions coupled to ATP synthesis. The ability of the plant cell to build and alter this membrane system is essential for efficient photosynthesis. A nucleotide translocator homologous to the bovine mitochondrial ADP/ATP carrier (AAC) was previously found in spinach thylakoids. Here we have identified and c
BACKGROUND: The Pediatric Heart Network designed a clinical trial to compare aortic root growth and other short-term cardiovascular outcomes in children and young adults with Marfan syndrome randomized to receive atenolol or losartan. We report here the characteristics of the screened population and enrolled subjects.METHODS AND RESULTS: Between 2007 and 2011, 21 clinical sites randomized 608 subj
Background: Family risks for urinary tract cancers (excluding kidney cancers) are known, but less is known about whether rare urinary tract cancer subtypes are also familial and if urinary tract cancers share familial risk for other (discordant) cancers. Objective: To investigate the impact of family history on urinary tract cancers (International Classification of Diseases version 7 code 181) and
Study region: Rukarara River Watershed (RRW), Rwanda. Study focus: DOC leaching has important environmental consequences for both terrestrial and aquatic ecosystems. This paper measures leached dissolved organic carbon (LDOC) and the factors controlling its variation in the RRW, a mixed agriculture and forest watershed in Rwanda. The study describes the relationship of LDOC with land use/land cove
INTRODUCTION: The influence of vaccination on composition of the human microbiome at distinct sites has been recognized as an essential component in the development of new vaccine strategies. The HPV vaccine is widely used to prevent cervical cancer; however, the influence of HPV vaccine on the vaginal microbiota has not been previously investigated. In his study, we performed an initial character
Prostate cancer bone metastasis is still not fully understood, and increased knowledge could aid in the development of better treatment options for patients in the future. This thesis focuses on microRNAs (miRNAs), which modulate gene expression in healthy and tumour cells. Using cell culture, animal and patient studies, we investigated the biological role of microRNA-96 (miR-96) and microRNA-379
Importance: Meningioma is the most common subsequent neoplasm following cranial irradiation among survivors of childhood cancer, but there are still uncertainties regarding the magnitude of the radiation dose-response association, potential modifiers of radiation risks, and the role of chemotherapy. Objective: To evaluate meningioma risk in survivors of childhood cancer following radiotherapy and
Purpose: Tru-cut biopsy is a minimally invasive technique used to obtain tissue samples for the diagnosis of tumors, especially in patients where primary surgery is not indicated. The aim of this study was to assess the adequacy, accuracy and safety of the tru-cut biopsy for diagnosis in gynecological cancer.Methods: A retrospective population-based review of 328 biopsies was conducted. The indica
The effect of pH on the kinetics of the bioelectrocatalytic reduction of H2O2 catalysed by horseradish peroxidase (HRP) has been studied at –50 mV vs. AgjAgCl on HRP-modified Au electrodes placed in a wall-jet flow-through electrochemical cell. Native HRP (nHRP) and a nonglycosylated recombinant form containing a six-histidine tag at the C-terminus, CHisrHRP, produced by genetic engineering of non
Aim: The aim of this study was to evaluate if a general school-based exercise intervention programme in pre-pubertal boys would render site-specific benefits in bone mineral accrual and gain in femoral neck structure. Methods: Eighty boys aged 7-9 years were included in a curriculum-based exercise intervention programme comprising 40 min of general physical activity per school day (200 min/week) f
