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Genistein, a tyrosine kinase inhibitor, inhibited cholecystokinin (CCK)-induced maximal amylase release from rat pancreatic acini by 18, 31, and 46% at concentrations of 100, 300, and 750 microM, respectively, after 30 min preincubation. Genistein similarly decreased amylase release stimulated by bombesin but not that stimulated by secretin or vasoactive intestinal peptide. The steps of stimulus-s
Conceptual design is the first phase in the design process in which all the requirements and design objectives are synthesized into conceptual alternatives. In practice today, major decisions regarding the buildings function, massing, and overall form are usually made during the first phase. Considering structural performance requirements during conceptual design enhances interdisciplinary interac
Aim of the MIRACHL project is the characterisation and monitoring of in-situ remediation of chlorinated hydrocarbon contamination using an interdisciplinary approach. Therefore, geophysical methods, as e.g. DCIP are used to investigate the remediation process.To interpret these geophysical field IP data, lab investigations with different kinds of bacteria are necessary to assess the sensitivity of
Objective: To determine the relative contribution of each of the following aspects: demographics, physical function, and patient-reported outcome measures (PROMs), including both physical and psychological constructs, to return to sport (RTS) (any level) one-year post anterior cruciate ligament reconstruction (ACLR). Design: Cross-sectional cohort study. Methods: We included data for 143 participa
Urban flood damage leads to major costs for private house owners, insurance companies, and water and wastewater utilities. Analysis of flood damage claims can be used to improve the understanding of the details of flood damage characteristics and reasons for drainage system failures. However, few studies have used data of this kind to investigate urban flood characteristics. We examined 3113 damag
Cerebral accumulation of amyloid-β is thought to be the starting mechanism in Alzheimer's disease. Amyloid-β can be detected by analysis of cerebrospinal fluid amyloid-β42 or amyloid positron emission tomography, but it is unknown if any of the methods can identify an abnormal amyloid accumulation prior to the other. Our aim was to determine whether cerebrospinal fluid amyloid-β42 change before am
BACKGROUND: The incidence of acute cardiovascular and cerebrovascular events in patients treated for complicated or uncomplicated peptic ulcer disease (PUD) has not been ascertained completely. METHOD: All patients with in-hospital treatment due to PUD between 1987 and 2007, who did not have any past history of acute or chronic cardiovascular or cerebrovascular disease, were identified through the
Purpose: Hodgkin lymphoma (HL) survivors are known to have increased cardiac mortality and morbidity. The risk of developing cardiovascular disease after involved node radiotherapy (INRT) is currently unresolved, inasmuch as present clinical data are derived from patients treated with the outdated mantle field (MF) technique. Methods and Materials: We included all adolescents and young adults with
The introduction of total prostate-specific antigen (tPSA) testing in serum has revolutionized the detection and management of men with prostate cancer. This review will highlight some of the exciting new developments in the field of prostate cancer screening in general and from our SPORE research program at Memorial-Sloan Kettering Cancer Center. First, it is important to understand that the inhe
Background: Repolarization prolongation can be the earliest electrophysiological change in ischemia, but its role in arrhythmogenesis is unclear. The aim of the present study was to evaluate the early ischemic action potential duration (APD) prolongation concerning its causes, expression in ECG and association with early ischemic ventricular fibrillation (phase 1A VF). Methods: Coronary occlusion
This deliverable summarizes the results of the co-development of innovative heritage-led regeneration plans in Replicators and builds on findings and activities coming from WP1-4 and WP7. RURITAGE’s 6 Replicators represent six very diverse rural areas in Europe and beyond (Austria, Norway, Germany, Slovenia, Italy and Turkey) and are acting as the main laboratories to test the RURITAGE approach. B
The Gaia-ESO Survey is a public spectroscopic survey that targeted ≲105 stars covering all major components of the Milky Way from the end of 2011 to 2018, delivering its final public release in May 2022. Unlike other spectroscopic surveys, Gaia-ESO is the only survey that observed stars across all spectral types with dedicated, specialised analyses: from O (Teff ∼ 30 000-52 000 K) all the way to K
A large part of the literature published in the ‘Global South’ is barely covered by bibliographic databases. Institutional policies increasingly require researchers globally to publish in ‘international’ journals, draining local infrastructures. The standard-setting power of ‘Global South’ scholars is minimised further. My main aim is to render visible the ways in which European academic libraries
The purpose of this paper is to measure living standards for the population of Chocó, Colombia, using four waves of the DHSurveys between 1990 and 2005. Recent maternal history allowed the construction of a pooled dataset of 3.055 children and 779 mothers. The concept of living standards is measured as the ability to ensure child and marriage survival subject to short term economic stress, which i
Syftet med denna studie var att se på prevalensen av dead regions, frekvensområden i cochlea där det inte finns fungerande inre hårceller (lliC), hos en grupp hörselskadade personer. De hörselskadade personerna har undersökts med det nya testet "Diagnosis for de ad regions" utvecklat av Brian Moore et al. (2000). Försökspersonernas resultat av Dead regionstest har sedan korrelerats med r
Populärvetenskaplig sammanfattning Spektroskopi handlar om teoretiska modeller och experiment där man observerar ljus som har växelverkat med materia. Spektroskopiska metoder används inom många olika ämnesområden som exempelvis kemi, fysik och biologi. Ett jordnära exempel på tillämpad spektroskopi är människans öga. Reflekterat ljus från olika föremål samlas in av linsen i ögat, avbildas på näthiIn this thesis a novel spectroscopic method consisting of a combination of frequency domain photon migration (FPDM) and gas in scattering media absorption spectroscopy (GASMAS) is developed, for assessment of the mean optical path length and gas absorption in porous media. The system stability is experimentally investigated and measurements are performed on balsa and pine wood to evaluate the rela
In the broader context of an increasing awareness of perspectives that for long have been a taboo in development thinking, such as ecology and gender questions, this study focuses on the subject of disability in development. By raising the question if disability can be mainstreamed the subject of disability will be compared with what can be learned from gender-mainstreaming. Conducted as a critica
I denna studie har det huvudsakliga syftet varit att undersöka hur de danska diftongerna i det fonologiska inventariet realiseras fonetiskt. De primära faktorer som har studerats är dels hur öppningsdiftongernas respektive slutningsdiftongernas "bana" ser ut, dels vilken variation det finns beroende på hur diftongen börjar eller slutar, dvs om t.ex [w]-läget kommer att uppnås oberoende a
Many coastal areas in Vietnam suffer from erosion. One of the worst affected areas is the Hai Hau beach, located in the Red River delta in northern Vietnam. Over the last hundred years, vast parts of the beach have eroded at an average rate of approximately 25 m per year. Important agricultural land has vanished into the sea and families have been forced to abandon their houses. The cause of the
This paper describes a study examining four different GARCH models AR(1)-GARCH(1,1), AR(1)-EGARCH(1,1), AR(1)-APGARCH(1,1) and AR(1)-GJR-GARCH(1,1), and their ability to predict future volatility and thereby providing more reliable estimates for Value-at-Risk. The study is based on daily observations for the return of the OMX Stockholm 30 Index, during the time period 31st December 1996 to 29th De
