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2024 - Art Of Astrometry

Studying the Milky Way’s dynamics using (limited) astrometry alone Paul McMillan, University of Leicester (Collaborators: Daniel Mikkola, David Hobbs, Teresa Antoja and the Gaia Consortium) Why use just astrometry? A lot of dynamics work focuses on this sample Why use just astrometry? We are the 98%! Basic maths 5×1.5×10! 6×3.3×10"≫ In other galaxies… Usually only have one component of velocity (l

https://www.astro.lu.se/sites/astro.lu.se/files/2024-06/2024%20-%20Art%20of%20Astrometry.pdf - 2026-07-18

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Robust and efficient numerical methods are an essential prerequisite for the computer based dynamical analysis of engineering systems. In vehicle system dynamics, the methods and software tools from multibody system dynamics provide the integration platform for the analysis, simulation and optimization of the complex dynamical behaviour of vehicles and vehicle components and their interaction with h

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E. coli continues to be a popular host organism for production of recombinant proteins. To obtain a high volumetric productivity at the cultivation stage, it is important to achieve a high cell density and a high specific productivity per cell. In many fed-batch processes, the substrate feed rate eventually becomes limited by the oxygen transfer capacity of the bioreactor. While biomass can contin

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Shortcomings of current techniques used for the intracerebral transplantation of ventral mesencephalic dopamine neurons include low graft survival, high variability, considerable implantation trauma and suboptimal graft integration. In order to overcome these limitations, we have adopted a microtransplantation approach which allows precise and reproducible implantation of ventral mesencephalon cel

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ABSTRACT: We plan to conduct a case-control study to investigate whether exposure to nitrogen dioxide (NO2) increases the risk of stroke. In case-control studies, selective participation can lead to bias and loss of efficiency. A two-phase design can reduce bias and improve efficiency by combining information on the non-participating subjects with information from the participating subjects. In ou

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Alzheimer’s disease is an aging related disorder of the mind, accountable for 60-80 percent of all cases of dementia. With its insidious progression and the decline of cognitive abilities, this disease is a major challenge for our society as a whole. This is because of the growing proportion of people living to advanced age and our current lack of capacity to prevent or even give effective symptom

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Conceptual design is the first phase in the design process in which all the requirements and design objectives are synthesized into conceptual alternatives. In practice today, major decisions regarding the buildings function, massing, and overall form are usually made during the first phase. Considering structural performance requirements during conceptual design enhances interdisciplinary interac

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“The stage is a playground, it’s not a serious place where you have to be at your best, ... it should be a playground.” Nir Ben Gal, choreographerDuring my years of study, and later as a performing artist, performance was never discussed conceptually and questions regarding audience interaction and stage fright were seldom raised. Further, musicians suffering from stage fright are most often refer

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Background: Concizumab is an anti-tissue factor pathway inhibitor monoclonal antibody in development as a once-daily, subcutaneous prophylaxis for patients with haemophilia A or haemophilia B with or without inhibitors. We aimed to assess the efficacy and safety of concizumab in patients with haemophilia A or B without inhibitors. Here we report the results from the confirmatory analysis cutoff. M

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Antibiotic resistance is a major threat for our society and finding novel antibacterial therapies is of greatimportance. In this thesis, we investigate bacterial sialic acid uptake inhibitors as a novel antibacterial approach.Bacteria do not biosynthesise sialic acid and therefore harvest it from the host. Sialic acid plays a crucial role forpathogenic bacteria, since it is used as a source of car

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Cerebral accumulation of amyloid-β is thought to be the starting mechanism in Alzheimer's disease. Amyloid-β can be detected by analysis of cerebrospinal fluid amyloid-β42 or amyloid positron emission tomography, but it is unknown if any of the methods can identify an abnormal amyloid accumulation prior to the other. Our aim was to determine whether cerebrospinal fluid amyloid-β42 change before am

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The introduction of total prostate-specific antigen (tPSA) testing in serum has revolutionized the detection and management of men with prostate cancer. This review will highlight some of the exciting new developments in the field of prostate cancer screening in general and from our SPORE research program at Memorial-Sloan Kettering Cancer Center. First, it is important to understand that the inhe

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Background: Repolarization prolongation can be the earliest electrophysiological change in ischemia, but its role in arrhythmogenesis is unclear. The aim of the present study was to evaluate the early ischemic action potential duration (APD) prolongation concerning its causes, expression in ECG and association with early ischemic ventricular fibrillation (phase 1A VF). Methods: Coronary occlusion

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My research is concerned with the co-optation of sustainability, feminism, and social justice within and by the fast fashion industry in Sweden. This stems from a desire to understand the acceleration of sustainability discourse and narratives built by brands (through communication, advertisement, marketing, and sustainability reporting) and how this shapes consumption. I argue that the dominating

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Room acoustic simulations are an important tool, both for design of spaces with satisfactory acoustics and for use in virtual reality experiences. Auralization of acoustic simulations are becoming more and more important in the context of Virtual and Augmented reality (VR and AR respectively), as the technology is used more and more in healthcare, culture and research. In this work, ray tracing si

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Some forests are burning in the US, the North of Italy gets flooded, and early spring days start to feel like midsummer. But it seems more important what kind of lunch to have for Tuesday, or which coffee blend is best for the new espresso machine. What makes people really care about climate change, not just in terms of awareness, but emotionally? This thesis aims to explore the motifs behind and

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De svenska kontorsmarknaderna i Stockholm, Göteborg och Malmö har sett ökade vakansgrader under de senaste åren. En viktig faktor bakom detta är anställdas preferenser efter Covid-19-pandemin. Även om närvaron på kontoren har börjat öka igen, har utnyttjandegraden sjunkit i Sverige, och hyresgäster prioriterar nu sin hyresportfölj och ytoptimering för att spara kostnader. Vakans i kontorsbyggnaderThe Swedish office markets especially in the three major cities Stockholm, Gothenburg, and Malmö have experienced increased vacancy rates in recent years. One key factor behind this is employees' preferences post the Covid-19 pandemic. Despite a gradual return to offices, the utilization rate has decreased in Sweden, prompting tenants to prioritize their lease portfolios and space optimization

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This thesis explores the application of machine learning techniques to improve the diagnosis of bloodstream infections (BSIs) using tabular data extracted from Swedish electronic health records maintained by Region Skåne. BSIs are associated with high mortality rates, especially when diagnosis and treatment are delayed. Traditional diagnostic methods like blood cultures are time-consuming and can

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I takt med att andelen variabel förnybar energi ökar i det svenska elsystemet krävs nya lösningar för att hantera utmaningar kopplade till intermittens, nätstabilitet och ekonomisk lönsamhet. Batterilagringssystem (BESS) lyfts fram som en av de mest lovande lösningarna för att möta dessa utmaningar. Detta examensarbete undersöker den tekniska och ekonomiska genomförbarheten av att integrera BESS mAs the share of variable renewable energy (VRE) increases in the Swedish electricity system, new solutions are needed to address challenges related to intermittency, grid stability, and economic viability. Battery energy storage systems (BESS) have been identified as one of the most promising solutions to meet these challenges. This master’s thesis investigates the technical and economic feasibili

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Optical spectroscopy is commonly used in technology and science today. The presence and concentration of a substance can be determined by its spectral signature, the typical wavelengths that are absorbed (or emitted) by the atoms or molecules. Standard absorption spectroscopy requires that the substance is clear and that the optical path-length is known to obtain quantitative information. Unfortun