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Based on polymerase chain reaction (PCR) utilizing degenerate primers directed to the second and sixth transmembrane domains of several G-protein-coupled neurotransmitter receptors and screening of a human B-lymphoblast cDNA library, we isolated a cDNA whose predicted amino acid sequence shows considerable homology with human chemoattractant receptors, e.g., 30% overall identity with the C5a anaph
Mobile communications have evolved with the commercial deployment of 5G and initial studies of 6G. New solutions and innovative technologies are being incorporated to reach the target requirements. One of the key technologies in mobile networks is massive multiple-input-multiple-output (MIMO). Increasing the number of antennas offers significant benefits in coverage, reliability, and spectral effi
OBJECTIVE: Screening for abdominal aortic aneurysm (AAA) using ultrasound in men reduces aneurysm-related mortality. Ambulatory screening and surveillance procedures facilitated by point-of-care ultrasound (POCUS) may improve adherence to screening programs. This proof-of-concept study evaluated whether infrarenal aortic diameter (IAD) can be accurately and interchangeably measured using handheld
Carbon capture using amine-based absorption is an established technology for the separation of gaseous CO2. It is used in the upgrading of gaseous fuels, and it has also been suggested that it could play a crucial role in the mitigation of climate change through post-combustion carbon capture and sequestration (CCS), and by creating carbon sinks through bioenergy CCS. One drawback of the existing
In synchrotrons, nonuniform fill patterns, which give rise to beam phase transients and a spread in synchrotron tune between bunches, have been observed to damp longitudinal coupled-bunch instabilities driven by higher-order modes in rf cavities. The transients are especially large in the presence of Landau cavities, which are used commonly in storage-ring light sources and particularly in the new
Mutations in GBA1 cause Gaucher disease and are the most important genetic risk factor for Parkinson’s disease. However, analysis of transcription at this locus is complicated by its highly homologous pseudogene, GBAP1. We show that >50% of short RNA-sequencing reads mapping to GBA1 also map to GBAP1. Thus, we used long-read RNA sequencing in the human brain, which allowed us to accurately quantif
Structural Health Monitoring (SHM) plays a vital role in maintaining the integrity of structures by providing continuous information about damage or anomalies. Vibration-based SHM, which focuses on the dynamic behavior of structures, offers insights into structural conditions through changes in dynamic properties. Among SHM approaches, damage localization is crucial for pinpointing the geometric l
Background: After neoadjuvant chemotherapy (NAC), about 20% of pts with muscle-invasive UC are found to have advanced pT-stage or lymph node involvement and 5-year overall survival (OS) of them is < 30%. Tumor samples from these pts may provide information about chemotherapy resistance, and may predict for the activity of new drugs given postoperatively. Alterations of FGFR3 gene represent a thera
Taking stance towards any topic, event or idea is a common phenomenon on Twitter and social media in general. Twitter users express their opinions about different matters and assess other people’s opinions in various discursive ways. The identification and analysis of the linguistic ways that people use to take different stances leads to a better understanding of the language and user behaviour on
In the sense of phenomenology, actions are special cases of acts of consciousness. Within semiotics, first Jan Mukařovský and then A. J. Greimas have established, in different terms, a distinction between instrumental actions and actions which carry their meaning in themselves. But this is insufficient to account for the variety of actions which comprises everything from the creation of artefacts,
Forty years ago, Viterbi published upper bounds on both the first error event (burst error) and bit error probabilities for Viterbi decoding of convolutional codes. These bounds were derived using a signal flow chart technique for convolutional encoders. In 1995, Best et al. published a formula for the exact bit error probability for Viterbi decoding of the rate R=1/2, memory m=1 convolutional enc
This thesis offers a detailed structural account of a full range of grammatical markers available for the expression of modality in Japanese. Twenty modal expressions are systematically analyzed in the context of a Western typological approach, with special attention being paid to the issue of subjectivity, in the spirit of the indigenous grammatical tradition. The approach is a distributional one
Purpose: The purpose of this study was to assess the alteration of retinal function by multifocal electroretinography and full-field electroretinography in patients with age-related macular degeneration treated with bevacizumab. Methods: We performed a prospective pilot study of 26 eyes of 26 previously treatment-naive patients with neovascular age-related macular degeneration receiving intravitre
The remarkable variation in plumage and morphological characters in the redpoll complex Carduelis flammea-hornemanni has puzzled taxonomists for several decades. In contrast, molecular studies have not revealed any genetic differentiation among the phenotypic redpoll forms. This could either be a result of high present-day gene flow or morphological differentiation following a rapid and recent pop
This paper studies how covenants are included in contracts between venture capitalists (VCs) and entrepreneurs. I show that VCs hold covenanted veto rights even though they are shareholders who have access to other powerful governance solutions. Unlike bank loans and bonds, venture capital (VC) contracts exhibit considerable variation in their contractual designs. I exploit this variation to confi
Males of all species of the parasitic wasp genus Nasonia use (4R,5S)-5-hydroxy-4-decanolide (RS) as component of their sex pheromone while only N. vitripennis (Nv), employs additionally (4R,5R)-5-hydroxy-4-decanolide (RR). Three genes coding for the NAD + -dependent short-chain dehydrogenases/reductases (SDRs) NV10127, NV10128, and NV10129 are linked to the ability of Nv to produce RR. Here we sho
I knew early that I wanted to work with leather, a material that I took interest in a while back but never had the time to explore it thoroughly. My thoughts are aimed toward refining a previous project as well as creating other supporting products for this. I wanted to challenge myself so I wrote in the brief that the designs should accommodate for the production method i had in mind: Saddle sti
