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Multilevel data occur frequently in many research areas like health services research and epidemiology. A suitable way to analyze such data is through the use of multilevel regression models. These models incorporate cluster-specific random effects that allow one to partition the total variation in the outcome into between-cluster variation and between-individual variation. The magnitude of the ef
Obesity and cigarette smoking are correlated through complex relationships. Common genetic causes may contribute to these correlations. In this study, we selected 241 loci potentially associated with body mass index (BMI) based on the Genetic Investigation of ANthropometric Traits (GIANT) consortium data and calculated a BMI genetic risk score (BMI-GRS) for 17,037 individuals of European descent f
The substitution of scandium in fullerene single‐molecule magnets (SMMs) DySc2N@C80 and Dy2ScN@C80 by lutetium has been studied to explore the influence of the diamagnetic metal on the SMM performance of dysprosium nitride clusterfullerenes. The use of lutetium led to an improved SMM performance of DyLu2N@C80, which shows a higher blocking temperature of magnetization (TB=9.5 K), longer relaxation
Summary: We studied effectiveness of osteoporosis treatment in women older than 80 years, who often are not included in clinical trials. Treatments were as effective on bone density and fractures as in younger women. Introduction: To study real-world effectiveness of osteoporosis treatment on BMD and fractures in the oldest old women (≥ 80 years) compared with women (60–79 years) in the clinical s
Objective: Studies that investigate predictive factors for spontaneous recovery (reversion) from mild cognitive impairment (MCI) are only beginning to emerge, and the long-term course of MCI is not properly understood. We aimed to investigate stability of the MCI diagnosis, predictors for reversion, as well as the trajectory of MCI over the course of 12 years. Materials and Methods: Data were draw
Aim: To illuminate the experience of an altered social context for patients with primary brain tumours living away from home while undergoing proton beam therapy. Design: A descriptive, qualitative cross-sectional interview study. Methods: Nineteen patients were interviewed between December 2015–August 2016, either during (N = 7) or before and after (N = 12) their proton beam therapy. A hermeneuti
HIV-1 transmission patterns within and between populations at different risk of HIV-1 acquisition in Kenya are not well understood. We investigated HIV-1 transmission networks in men who have sex with men (MSM), injecting drug users (IDU), female sex workers (FSW) and heterosexuals (HET) in coastal Kenya. We used maximum-likelihood and Bayesian phylogenetics to analyse new (N = 163) and previously
Optimum operating conditions of a fuel cell will provide its maximum efficiency and the operating cost will be minimized. Thus, operation optimization of the fuel cell is essential. Neural networks can simulate systems without using simplifying assumptions. Therefore, the neural network can be used to simulate complex systems. This paper investigates the effects of important parameters, i.e., temp
In recent years, increasing inlet temperature of gas turbines has far exceeded the melting point of the metal materials. Film cooling technology has widely been used to protect gas turbine blades from erosion of the high-temperature gases. The film cooling performance can be improved by optimization of the hole configurations. Results show that the backward injection hole has a smaller exit moment
Purpose of review: The main goal of this narrative review is to assess whether physical activity (PA) influences peak bone mass and fracture risk. Recent findings: Several randomized controlled trials (RCT) show that short-term PA intervention programs in childhood improve the accrual of bone mineral. There are now also long-term controlled PA intervention studies demonstrating that both boys and
Steam is a common medium in thermal engineering. When it flows through a throttling element, the aerodynamic noise may occur due to the disturbance. In this investigation, superheated steam flowing through a Venturi tube, one of the main parts in a temperature and pressure regulation valve, at different thermal conditions is studied to analyze to effects of heat transfer on the acoustic power. Wit
Introduction: Obese primiparous women with induction of labor are at high risk for a cesarean section. There are contradictory results regarding time in induced labor in relation to maternal body mass index (BMI). It is important to characterize the course of induced labor to prevent unnecessary cesarean section. We aimed to evaluate whether the duration of labor was associated with maternal BMI i
In the present paper, the heat transfer of gravity-driven dense particle flow around five different shapes of tubes is numerically studied using discrete element method (DEM). The velocity vector, particle contact number, particle contact time and heat transfer coefficient of particle flow at different particle zones around the tube are carefully analyzed. The results show that the effect of tube
Insects have evolved diverse and remarkable strategies for navigating in various ecologies all over the world. In particular, central place foragers, such as bees and ants, have become renowned for their fascinating navigational capabilities. At the heart of insect navigation lies a brain area known as the central complex (CX). Functionally, the CX integrates world-centric sensory information with
BACKGROUND: HIV and other sexually transmitted infections are a growing problem in the military personnel of Africa, and information about this problem in Guinea-Bissau is lacking. The aims of this study were to determine the prevalence and trends of the HIV epidemics in the military forces of Guinea Bissau and to explore possible risk factors for HIV infection. METHODOLOGY: Repeated cross-sectio
Frailty is a consequence of advanced aging, where the frailty phenotype tries to capture overall decline in health. Frailty involves multiple physiological systems that are intrinsically inter-related and with highly complex interactions. Frailty is closely linked to musculoskeletal health; musculoskeletal functioning is a key component in quantifying frailty, while at the same time, frailty is as
