Sökresultat

BACKGROUND. In recent studies serum levels of human glandular kallikrein 2 (hK2) demonstrated significant differences in pathologically organ-confined versus non-organ-confined prostate cancer (Pca). In this study we investigated whether hK2 adds independent information when considered together with traditionally used parameters to predict organ confined (pT2a/b) PCa. METHODS. Serum levels of hK2,

Density functional calculations have been used to compare various geometric, electronic and functional properties of iron and cobalt porphyrin (Por) and corrin (Cor) species. The investigation is focussed on octahedral MII/III complexes (where M is the metal) with two axial imidazole ligands (as a model of b and c type cytochromes) or with one imidazole and one methyl ligand (as a model of methylc

This paper shows how discontinuities in the process of drug delivery enable but also underdetermine the isolation of a culprit in adverse medication events. A case example illustrates how we are forced to abandon conceptualizations of blame that assume a dichotomy (either culpable or not), and shift instead to a more nuanced version that estimates the degree to which an actor desired, generated, o

This paper includes 19 saxicolous species of Caloplaca from North and Central America that are characterized by distinctive elongated marginal lobes, non-paraplectenchymatous hypothecium, and presence of anthraquinones. In various ways this group has been referred to as Caloplaca section Gasparrinia or even separated at the generic level. The group, however, is not regarded as natural and conseque

The aim of the study was to investigate the main and the interaction effects of the demand-control-support (DCS) model on women’s and men’s health in a Swedish telecom company. According to the DCS model, work that is characterized by high demands, low decision latitude, and low support decreases health and well-being. Furthermore, control and support are assumed to interact in protecting against

Social capital is often operationalised as social participation in the activities of the formal and informal networks of civil society and/or as generalised trust. Social participation and trust are two aspects of social capital that mutually affect each other, according to the literature. In recent years there has been an increased attention to the fact that generalised trust decreases for every

Background Despite the fact that severe itch is common in many dermatological diseases, the therapeutic arsenal against itching is limited. From neurophysiological experiments, using a new technique termed cutaneous field stimulation, it is known that acute itch can be effectively relieved by stimulation of cutaneous nociceptors. Methods We tested the effects of cutaneous field stimulation (25 mi

The Ag II spectrum emitted from hollow cathode discharges has been recorded in the region 940–8500 Šwith Fourier transform and high dispersion photographic instruments. 311 lines have been classified and measured at high accuracy (±0.03–0.003 cm-1 above 2000 Ŭ ±0.002–0.0005 Šin the VUV region). Improved energy level values have been derived from the lines, and 24 new odd levels have been found. Th

Using [C-14]methylamine as an analogue of ammonium, the kinetics and the energetics of NH: transport were studied in the ectomycorrhizal fungus, Paxillus involutus (Batsch) Fr. The apparent half-saturation constant (K-m) and the maximum uptake rate (V-max) for the carrier-mediated transport derived from the Eadie-Hofstee transformation were 180 mu M and 380 nmol (mg dry wt)(-1) min(-1,) respective

Neurosphere cultures are widely used to propagate multipotent CNS precursors, but their differentiation into neurons or oligodendrocytes is rather poor. To elucidate fate determination in this system, we examined the expression and function of candidate transcription factors in neurospheres derived from different CNS regions during development and adulthood. We observed prominent down-regulation o

The complexation of Cd(II) and Cd(II)-phthalate at the goethite/water interface were investigated by EXAFS and IR spectroscopy, by batch adsorption experiments and by potentiometric titrations at 298.15 K. The EXAFS spectra showed Cd(IT) to form only inner-sphere corner-sharing complexes with the goethite surface sites in the presence and absence of phthalate. EXAFS spectra also showed the presenc

Harmful algal blooms (HABs) have occurred with increasing frequency in recent years with eutrophication and other anthropogenic alterations of coastal ecosystems. Many of these blooms severely alter or degrade ecosystem function, and are referred to here as ecosystem disruptive algal blooms (EDABs). These blooms are often caused by toxic or unpalatable species that decrease grazing rates by plankt

An experimental system was developed for the rapid measurement of the aspiration/transfer efficiency of aerosol samplers in a wind tunnel. We attempted to measure the aspiration and particle transfer characteristics of two inlets commonly used for sampling airborne Particulate Matter ( PM): the 'Total Suspended Particulate' or TSP inlet, and the louvered 'dichotomous sampler inlet' typically used

The chapter by definition focuses on Swedish research and treatment practice in the area of comorbiditity. Three “ethiological” lines of comorbidity is outlined. it thus seems warranted to look upon patients with a precipitating psychiatric diagnosis and a consequent problem of alcohol and/or substance abuse as one specific model/type (1). A second type representting the drug and substance depende