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The current form-giving activity in industrial design is characterized by explorations that depend on the individual capability to mentally manipulate a solution space from which to select and express the intended result. Designers often rely on artistic experimentation, aesthetic inspiration, or product specifications. These approaches often lead to satisfactory results, but they could be augment

At Lund University Faculty of Technology a growing number of teachers develop active student learning methods. These methods can have some advantages in obtaining certain objectives with higher education. To take responsibility for the own learning process and also to learn how to independently handle information and use it in an adequate way are important skills to achieve during an university ed

In the present thesis molecular genetic methods were used to address different biological and clinical aspects of Philadelphia (Ph) chromosome-positive leukemias and the BCR and ABL genes. In the first study, children with Ph-positive chronic myeloid leukemia (CML) were found to have essentially the same breakpoint locations in BCR as adults, a pattern which differs from the one seen in Ph-positiv

Popular Abstract in Swedish BAKGRUND Hjärnskador till följd av otillräckligt blodflöde eller skallskador drabbar varje år ett stort antal människor i vårt land. Otillräckligt blodflöde till hjärnan (cerebral ischemi) uppträder vid en rad kliniska tillstånd, exempelvis slaganfall (stroke), hjärtstillestånd och gravt sänkt blodtryck. Hjärnskador till följd av våld mot huvudet (traumatiska hjärnskadIschemic and traumatic brain damage are major causes of disability and death. While much effort has been spent to develop pharmacological treatments for these conditions, no neuroprotective drugs are in clinical use. Neuronal death following ischemia and trauma occurs in selected cell populations of the brain at various time points after the insult. It is believed that death of neurons are in part

The effects of various concentrations of plasmin and activated protein C on the factor VIII procoagulant activity (VIII:C) and coagulant antigen (VIII:CAg) were studied in factor VIII concentrates and normal plasma. Small amounts (0.1 CTA U/ml) of plasmin rapidly destroyed VIII:C, and affected, but did not destroy VIII:CAg, in factor VIII concentrates. In normal plasma larger amounts of plasmin (1

The extracellular matrix (ECM) is a complex structural entity surrounding and supporting cells present in all tissue and organs. Cell-matrix interactions play fundamental roles during embryonic development, morphogenesis, tissue homoeostasis, wound healing, and tumourigenesis. Cell-matrix communication is kept in balance by physical contact and by transmembrane integrin receptors providing the dyn

An isolated, yet virtually intact contour feather (FUM-1980) from the lower Eocene Fur Formation of Denmark was analysed using multiple imaging and molecular techniques, including field emission gun scanning electron microscopy (FEG-SEM), X-ray absorption spectroscopy and time-of-flight secondary ion mass spectrometry (ToF-SIMS). Additionally, synchrotron radiation X-ray tomographic microscopy (SR

In the trend of academic entrepreneurship, practical and direct contribution of university research to the society has been emphasized, in which university scientists have increasingly engaged in commercial activities, university-industry relationships, and technology transfers. However, this trend has aroused concern about a potentially negative impact on the tradition of open science. Drawing on

Objective: To analyze the age- and trial-specific effects of the breast cancer screening trials with mammography in Malmö, Stockholm, and Göteborg. Methods: The original trial files were linked to the Swedish Cancer and Cause of Death Registers to obtain date of breast cancer diagnosis and date and cause of death. Relative risks and 95% confidence intervals were calculated using the evaluation mod

This paper investigates the association between infant mortality and macroeconomic shocks in the Dominican Republic, using the 2002 and 2007 Demographic and Health (DHS) surveys. The article starts by reviewing the recent evolution of macroeconomic and social indicators in the country, as well as infant mortality trends calculated from the DHS surveys. It then proceeds to estimate logit and s

Bakgrund: Fallolyckor har ökat den senaste tiden och orsakar stora kostnader för samhället samt lidande för den drabbade. Det är viktigt att sätta in insatser i fallprevention för att motverka detta. Socialstyrelsen har samordnat en kampanj på uppdrag från regeringskansliet för dessa insatser. I dagsläget används instrument med mått som är ospecifika samt svåra att kvantifiera för att utvärdera fa

Labour and environmental provisions became a prominent feature in trade agreements nowadays. Since 2011, the European Union devotes a whole chapter in its trade agreements to these issues - the trade and sustainable development (TSD) chapter. This paper argues that an important aspect of the EU’s approach are the institutional mechanisms which monitor the implementation of the TSD chapter. Applyin

Since April 2017, legislation fining people in ‘encampments’ in public spaces was enacted in Copenhagen. This regulation was tightened by July 2018 be-coming an effective ban, where the subject of the fine was expelled from the administrative limits of the municipality. The measure comes as an ineffective way to deal with homelessness as it does not address the conditions that lead to it, working