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Diagnostic measurements and pharmacokinetic studies were performed in 17 patients with various kinds of malignant, premalignant and benign lesions in the head and neck region by means of point monitoring laser-induced fluorescence. For marking different types of tissue, delta-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) was used. The ALA-induced PpIX synthesis was monitored at differ

Purpose: Photodynamic therapy utilising delta-aminoleuvlinic acid-induced protoporphyrin IX photosensitisation, was evaluated as a treatment modality for nonmelanoma skin malignancies of the eyelids and the periocular skin, Methods: Photodynamic therapy with laser light at 635 nm was performed in 13 patients with 19 basal cell carcinomas and one patient with 3 cutaneous T-cell lymphoma lesions. A

Considering that businesses, whether they operate on a global or a domestic market, are affected by globalization, cross-cultural management is without doubt an urgent topic in current management and education. However, despite this urgency and the commendable intention behind the endeavour to enhance people’s cultural knowledge, current models on national cultures are problematic since they rely

Popular Abstract in Swedish I avhandlingen studeras plasminogenaktiverings-systemets (PA-systemets) komponenter i livmoderslemhinnan. PA-systemet reglerar omvandlingen av plasminogen till plasmin. Plasminogen är ett inaktivt enzym som finns överallt i kroppsvätskor samt i kroppens olika organ. Aktiveringen katalyseras av aktivatorer, antingen urokinase plasminogen activator (uPA) eller tissue plasThe release of urokinase plasminogen activator (uPA) from endometrial stromal cells decreased after progesterone stimulation, due to upregulation of PA inhibitor 1 (PAI-1) and uPA receptor (uPAR). Subsequently, the uPA:PAI-1 complex was internalized and degraded via uPAR. Predecidual cells in the late secretory phase expressed PAI-1 and uPAR, supporting a specific role for predecidual cells in the

Popular Abstract in Swedish Den pågående ökningen av växthusgaser i atmosfären orsakar en ökning av den globala medeltemperaturen. En viktig påverkande faktor för koncentrationen koldioxid (CO2) i atmosfären är utbytet mellan atmosfären och biosfären; fotosyntesen tar upp CO2 och respirationen släpper ut CO2, vilket resulterar i ett nettoutbyte. För att öka vår förståelse av den spatiala och tempoThe ongoing increase in atmospheric greenhouse gas concentrations causes an increase in the global mean air temperature. One important moderator of the atmospheric carbon dioxide (CO2) concentration is the gas exchange between the atmosphere and the biosphere; photosynthesis extracts and respiration releases CO2, resulting in a net exchange. A variety of methods are used to improve our understandi

Popular Abstract in Swedish Utvecklingen av offentlig sektor har de senaste årtiondena till stor del påverkats av New Public Management. Som en konsekvens av detta har en ”marknadisering” av offentliga verksamheter och organisationer skett. Denna ”marknadisering” har resulterat i att det finns organisationer i offentlig sektor som varken passar in på beskrivningen av offentliga organisationer elleDuring the last decades the influence of New Public Management and the “marketisation” of public services, have given us organisations in the public sector that fit neither the mould of what constitutes public sector organisations nor that of private companies. Instead, we now have so-called hybrid organisations. These have become an attractive alternative to the more “bureaucratic” public agencie

We evaluated the use of two radiolabeled lambda DNA/Hpa II substrates to detect 5'-->3', 3'-->5' single and double stranded DNA dependent exonuclease and phosphatase activities found as contaminants in restriction and modifying enzyme preparations. Looking for the meaning of the radioactive assays results in a real cloning experience, we performed a cloning simulation assay using the same conditio

US-based philanthropies have long contributed to environmental conservation through non-repayable donations, but some are now beginning to embrace novel investment strategies that are profit-orientated. From the vantage points of political economy and geopolitics, this article investigates the potential ramifications of this shift in funding for large-scale marine protected areas (LMPAs), which ha

Biobanks are essential infrastructures in current health and biomedical research. Advanced scientific research increasingly relies on processing and correlating large amounts of genetic, clinical and behavioural data. These data are particularly sensitive in nature and the risk for privacy invasion and misuse is high. The EU General Data Protection Regulation (GDPR) developed and increased harmoni

Mt4 is a cDNA representing a phosphate-starvation-inducible gene from Medicago truncatula that is down-regulated in roots in response to inorganic phosphate (Pi) fertilization and colonization by arbuscular mycorrhizal fungi. Split-root experiments revealed that the expression of the Mt4 gene in M. truncatula roots is down-regulated systemically by both Pi fertilization and colonization by arbuscu

The vertebrate gene repertoire is characterized by “cryptic” genes whose identification has been hampered by their absence from the genomes of well-studied species. One example is the Bmp16 gene, a paralog of the developmental key genes Bmp2 and -4. We focus on the Bmp2/4/16 group of genes to study the evolutionary dynamics following gen(om)e duplications with special emphasis on the poorly studie

Models suggest that climate change mitigation now depends on negative emissions, i.e. the large‐scale removal of carbon dioxide from the atmosphere. This assumption has been criticised in the climate policy literature for being unfeasible and unjust. This article asks how critical scholars can make sense of, and contribute to these debates. It suggests that negative emissions can be conceived of a

Climate change's effect on sea surface temperature (SST) at the regional scale vary due to driving forces that include potential changes in ocean circulation and internal climate variability, ice cover, thermal stability, and ocean mixing layer depth. For a better understanding of future effects, it is important to analyze historical changes in SST at regional scales and test prediction techniques