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Protein aggregation is a key process in the development of many neurodegenerative disorders, including dementias such as Alzheimer's disease. Significant progress has been made in understanding the molecular mechanisms of aggregate formation in pure buffer systems, much of which was enabled by the development of integrated rate laws that allowed for mechanistic analysis of aggregation kinetics. Ho

Recent studies have explored the influence of obesity and critical illness on ciprofloxacin pharmacokinetics. However, variation across the subpopulation of individuals with obesity admitted to the intensive care unit (ICU) with varying renal function remains unexamined. This study aims to characterize ciprofloxacin pharmacokinetics in ICU patients with obesity and provide dose recommendations for

Objective: To translate and cross-culturally adapt the Stroke Self-Efficacy Questionnaire (SSEQ) from English to Swedish and to evaluate psychometric properties of the questionnaire. Methods: A cross-sectional study design, where the translation followed a process including initial translation, synthesis, backward translation, expert committee, and pretest. Content validity was assessed using Cont

Digitalization and emergence of new technologies including Artificial Intelligence has shaped new organizational principles for the functioning of economies and societies globally. Technology has also changed the landscape for taxation and interactions between tax administration and taxpayers. Recently various models of electronic reporting and invoicing, split-payment mechanisms as well electroni

Taking point of departure in two black dolls that once belonged to Sophie Christine Oxholm and to the family of Clara Asenath Schultz, the article explores aspects of childhood and childcare in colonial homes. Both girls grew up in the Danish West Indies in the nineteenth century and were cared for by African Caribbean nannies – the likely makers of the dolls. Drawing on historical and literary so

This article examines limits to per capita living space (i.e. living smaller and/or sharing living space) as a measure for achieving sufficiency in housing. It studies the acceptance, motivation and side-effects of voluntarily reducing living space in five European Union countries: Germany, Hungary, Latvia, Spain and Sweden. Insights are derived from an extensive collection of qualitative empirica

Multiple myeloma (MM) is an incurable malignancy of plasma cells. Epidemiological studies indicate a substantial heritable component, but the underlying mechanisms remain unclear. Here, in a genome-wide association study totaling 10,906 cases and 366,221 controls, we identify 35 MM risk loci, 12 of which are novel. Through functional fine-mapping and Mendelian randomization, we uncover two causal

Children's time investments in various activities may be important for reducing socioeconomic status (SES) gaps in educational and mental health outcomes. Using detailed time use diaries of Australian children aged 4–14, we observe that children from low SES backgrounds spend more time on digital media and less time on out-of-school enrichment activities, organised or for leisure. We explain the S

It has been established across several contexts that political attitudes are informed by heritable factors. However, it remains unclear how much of the stability we observe in political attitudes can be ascribed to environmental factors and how much of the stability is due to genetics. In this paper we show, using a unique three-wave panel dataset of twins (N = 2471) spanning ten years, that both

My written contribution responds to the questions: How des your practice relate to placemaking? How is it possible to use sense of place as material and starting point for research or artistic work? What methods do you use for co-creation and relationship building in relation to place?

The paper examines how the increasing datafication of society and advancements in artificial intelligence (AI) offer new empirical opportunities to better understand the Minimum Content of Nationality (MCN). Despite the critical importance of the MCN in statelessness, it has largely been ignored in academic and policy circles. The ambiguity that results from this lack of engagement greatly complic

Starch is generally regarded as safe for human consumption and has therefore attracted interest for several applications as medicinal products. This chapter focuses specifically on starch microspheres as carriers for drug delivery and as a medical device for, for example, vascular occlusion. Several methods for the preparation of starch microspheres by chemical or physical cross-linking are presen

Crop pests, such as aphids and bark beetles, represent a big challenge for agriculture worldwide. Due to their high adaptability and more suitable conditions because of climate change, they can thrive on a large number of hosts. One of the strategies to control the population of these pests in agricultural areas is the use of pheromones, either to lure them, repel them or to attract predators as a

Academic journals, archives, and repositories are seeing an increasing number of questionable research papers clearly produced using generative AI. They are often created with widely available, general-purpose AI applications, most likely ChatGPT, and mimic scientific writing. Google Scholar easily locates and lists these questionable papers alongside reputable, quality-controlled research. Our an