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Background: Persistent circulating cell-free tumor DNA (ctDNA) detection during neoadjuvant treatment of early-breast cancer (EBC) indicates high-risk disease. Detection of ctDNA post-resection of EBC (molecular residual disease, MRD) indicates occult metastatic disease and impending disease relapse. For ctDNA to be integrated into EBC management, accessible and scalable diagnostic tools are requi

Technical measurements allow an objective assessment of MSD risk factors at work. There is a need for common standards regarding data collection and processing, as well as an exchange platform storing measurement data of occupational physical activity and workload for further analysis. Several research institutes started a feasibility study to work on developing standards for assessment of risk fa

We have used the FERMI free-electron laser to perform time-resolved photoelectron imaging experiments on a complex group of resonances near 15.38 eV in the absorption spectrum of molecular nitrogen, N2, under jet-cooled conditions. The new data complement and extend the earlier work of Fushitani et al. [Opt. Express 27, 19702–19711 (2019)], who recorded time-resolved photoelectron spectra for this

BACKGROUND Trials evaluating the omission of completion axillary-lymph-node dissection in patients with clinically node-negative breast cancer and sentinel-lymph-node metastases have been compromised by limited statistical power, uncertain nodal radiotherapy target volumes, and a scarcity of data on relevant clinical subgroups. METHODS We conducted a noninferiority trial in which patients with cli

Background: The recent expansion of immunotherapy for stage IIB/IIC melanoma highlights a growing clinical need to identify patients at high risk of metastatic recurrence and, therefore, most likely to benefit from this therapeutic modality. Objective: To develop time-to-event risk prediction models for melanoma metastatic recurrence. Methods: Patients diagnosed with stage I/II primary cutaneous m

This roadmap, developed through collaborative discussions at the recent AI PolicyResearch Summit, reflects a shared vision for advancing research on responsibleAI policy and governance. It emphasizes the critical role of policy research inensuring that AI development is guided by robust evidence, ethicalconsiderations, and a commitment to sustainability and inclusivity. By prioritizingtransparency

OBJECTIVE: Glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR) is expressed on CD4(+) effector memory T cells and regulatory T cells; however, its role on these functionally opposing cell types in atherosclerosis is not fully understood.APPROACH AND RESULTS: Low-density lipoprotein receptor-deficient mice (Ldlr(-/-)) were lethally irradiated and reconstituted with e

Chlamydia trachomatis is responsible for both trachoma and sexually transmitted infections, causing substantial morbidity and economic cost globally. Despite this, our knowledge of its population and evolutionary genetics is limited. Here we present a detailed phylogeny based on whole-genome sequencing of representative strains of C. trachomatis from both trachoma and lymphogranuloma venereum (LGV

According to our current cosmological model, galaxies like the Milky Way are expected to experience many mergers over their lifetimes. The most massive of the merging galaxies will be dragged towards the disc plane, depositing stars and dark matter into an accreted disc structure. In this work, we utilize the chemodynamical template developed in Ruchti et al. to hunt for accreted stars. We apply t

Popular AbstractDetta är en histora över teorier om ojämnt utbyte och deras upphovsmän. Den börjar med merkantilismen och Richard Cantillons jordvärdeteori, ger en kort beskrivning av tidig klassisk ekonomi och Gerald Fitzhugh. Bland det tidiga 1900-talets marxistiska ekonomer spelade ojämnt utbyte en roll i Otto Bauers tolkning av nationalistiska motsättningar, och i Henryk Grossmanns verk som enThis is a history of theories and theorists of unequal exchange. Starting with mercantilists and Richard Cantillon's theory based on land values, it briefly covers the early Classical economists and Gerald Fitzhugh. Among early 20th century Marxist economists, unequal exchange appeared in Otto Bauer's explanation of nationalist antagonism, and in Henryk Grossmann as countering the breakdown of cap

For women and children, especially those who are poor and disadvantaged, to benefit from primary health care, they need to access and use cost-effective interventions for maternal, newborn, and child health. The challenge facing weak health systems is how to deliver such packages. Experiences from countries such as Iran, Malaysia, Sri Lanka, and China, and from projects in countries like Tanzania

This thesis investigates advanced Swedish students’ development of three grammatical phenomena: subject-verb concord, prepositions and article use in compositions and translations. In order to describe the students’ development of these categories, actual errors are related to potential errors forming so called ‘error scores’. When the error score for the first test opportunity is compared with th

The Swedish model of industrial relations is analyzed with respect to some closely related dimensions: collective agreements - legislation, cooperation - confrontation, self-regulation - state regulation and centralisation - decentralisation. Both the historical development and the present state of the model are discussed. In an analytical table the dimension self-regulation - state regulation is

Rheumatoid arthritis-associated joint pain is frequently observed independent of disease activity, suggesting unidentified pain mechanisms. We demonstrate that antibodies binding to cartilage, specific for collagen type II (CII) or cartilage oligomeric matrix protein (COMP), elicit mechanical hypersensitivity in mice, uncoupled from visual, histological and molecular indications of inflammation. C

Myeloid-derived suppressor cells (MDSCs) are known to contribute to immune evasion in cancer. However, the function of the human granulocytic (G)-MDSC subset during tumor progression is largely unknown, and there are no established markers for their identification in human tumor specimens. Using gene expression profiling, mass cytometry, and tumor microarrays, we here demonstrate that human G-MDSC

To provide a valid consent to – or refusal of – medical intervention, a patient must be legally capable to decide. This dissertation evaluates and compares when the assessment of mental abilities to refuse – or consent to – somatic medical intervention is required in England, Russia and Sweden, and what criteria must be applied to assess the ability to decide about somatic medical interventions in

We report the discovery from K2 of a transiting planet in an 18.25-d, eccentric (0.19 ± 0.04) orbit around K2-99, an 11th magnitude subgiant in Virgo. We con- firm the planetary nature of the companion with radial velocities, and determine that the star is a metal-rich ([Fe/H] = 0.20 ± 0.05) subgiant, with mass 1.60+0.14 -0.10 M⊙ and radius 3.1 ± 0.1 R⊙. The planet has a mass of 0.97 ± 0.09 MJup a

Arbetsordning för Lunds universitet FÖRSÄTTSSIDA STYRDOKUMENT Lunds universitets arbetsordning Typ av styrdokument: Arbetsordning Definition av typen av styrdokument: Enligt 2 kap. 2 § första stycket 8 p högskoleförordningen (1993:100) ska styrelsen för en högskola besluta om en arbetsordning med viktigare föreskrifter om högskolans övergripande organisation, delegering av beslutanderätt, handlägg

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2025-12/lunds-universitets-arbetsordning-251217.pdf - 2026-04-28