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Pseudouridine synthases (PUSs) catalyze the isomerization of uridine (U)-to-pseudouridine (Ψ) and have emerging roles in development and disease. How PUSs adapt gene expression under stress remains mostly unexplored. We identify an unconventional role for the Ψ "writer" PUS10 impacting intracellular innate immunity. Using Pus10 knockout mice, we uncover cell-intrinsic upregulation of interferon (I
BACKGROUND: Skin cancer is a prevalent and clinically significant condition, with early and accurate diagnosis being crucial for improved patient outcomes. Dermoscopy and artificial intelligence (AI) hold promise in enhancing diagnostic accuracy. However, the impact of image quality, particularly high dynamic range (HDR) conversion in smartphone images, on diagnostic performance remains poorly und
Infrared excesses associated with debris disk host stars detected so far peak at wavelengths around ~100 μm or shorter. However, 6 out of 31 excess sources studied in the Herschel Open Time Key Programme, DUNES, have been seen to show significant—and in some cases extended—excess emission at 160 μm, which is larger than the 100 μm excess. This excess emission has been attributed to circumstellar d
An atomistic understanding of the photoinduced spin-state switching (PSS) within polynuclear systems of d4-d7 transition metal ion complexes is required for their rational integration into light-driven reactions of chemical and biological interest. However, in contrast to mononuclear systems, the multidimensional dynamics of the PSS in solvated molecular arrays have not yet been elucidated due to
Background: Diabetes is presently classified into two main forms, type 1 and type 2 diabetes, but type 2 diabetes in particular is highly heterogeneous. A refined classification could provide a powerful tool to individualise treatment regimens and identify individuals with increased risk of complications at diagnosis. Methods: We did data-driven cluster analysis (k-means and hierarchical clusterin
Atopic dermatitis (AD) is a complex disease with elevated risk of respiratory comorbidities.1,2 Severely affected patients are often treated with immune-modulating systemic drugs.3,4 On March 11th 2020, the World Health Organization declared the 2019 novel coronavirus severe acute respiratory syndrome (SARS-Cov-2) epidemic to be a pandemic. The number of cases worldwide is increasing exponentially
Postadress Box 192, 221 00 LUND Besöksadress LUX, Helgonavägen 3, LUND Telefon 046-222 00 00 Webbadress http://www.ht.lu.se Fakul te tss tyre lsens arbe tsutskot t Humanistiska och teologiska fakulteternas handlingsplan för jämställdhet, lika villkor och mångfald 2024–2026 HT-fakulteternas JLM-plan är ett fakultetsövergripande dokument som omfattar HT:s samtliga verksamheter. Synpunkter och inspel
Civilingenjör i datateknik | LTH, Lunds Tekniska Högskola Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera oc
https://www.lth.se/utbildning/datateknik300/ - 2026-04-27
Civilingenjör i lantmäteri | LTH, Lunds Tekniska Högskola Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera oc
https://www.lth.se/utbildning/lantmateri/ - 2026-04-27
Postadress Box 192, 221 00 LUND Besöksadress LUX, Helgonavägen 3, LUND Telefon 046-222 00 00 Webbadress http://www.ht.lu.se Fakul te tss tyre lsens arbe tsutskot t Humanistiska och teologiska fakulteternas handlingsplan för jämställdhet, lika villkor och mångfald 2024–2026 HT-fakulteternas JLM-plan är ett fakultetsövergripande dokument som omfattar HT:s samtliga verksamheter. Synpunkter och inspel
Postadress: LUX Box 192, 221 00 Lund Besöksadress: Helgonavägen 3, Lund Telefon: 046-222 64 74, 046-222 00 00 E-post: Charlotte.Tornbjer@ht.lu.se Hemsida: http://www.ht.lu.se Dri f tsenhet LUX Char lo t te Tornbjer , enhe tschef 2018-09-01 LUX – för anställda med arbetsplats på LUX På LUX har Centrum för teologi och religionsvetenskap, Filosofiska institutionen, Historiska institutionen, Instituti
https://www.fil.lu.se/fileadmin/user_upload/fil/dokument/Intranaetet/LUX_foer_anstaellda_2018.pdf - 2026-04-27
The purpose of the thesis is to analyse the problems of hybrid mismatch arrangements within the EU and how single taxation, which requires income to be taxed once, not more or less, can be secured under EU law. After the amendments of the Parent-Subsidiary Directive (PSD), where an anti-hybrid rule was enacted, the legal environment for companies within the European Union changed. Parent compani
Asylum Seeker Situation Urgent in Europe Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus Areas Business and Human Rights Internat
https://rwi.lu.se/2015/04/21/asylum-seeking-situation-urgent/ - 2026-04-28
föreläsning 2 FÖRELÄSNING 2 FRITS GÅVERTSSON FILOSOFISKA INSTITUTIONEN, LUNDS UNIVERSITET Rum 312 Kungshuset, Lundagård, 222 22 Lund, SWEDEN e-mail: frits.gavertsson@fil.lu.se tel:+46768482707 Praktisk filosofi vt-14 FPRA11:2 (Kritiskt tänkande i värdefrågor) Välvillighetsprincipen När man skall ta ställning till andras resonemang behöver man allt som oftast tolka dem. Följande princip bör då
https://www.fil.lu.se/media/utbildning/dokument/kurser/FPRA11/20141/frelsning_2.pdf - 2026-04-28
We announce the discovery of K2-139 b (EPIC 218916923 b), a transiting warm-Jupiter (Teq = 547± 25 K) on a 29-d orbit around an active (logR' HK =-4.46±0.06) K0V star in K2 Campaign 7.We derive the system's parameters by combining the K2 photometry with groundbased follow-up observations. With a mass of 0.387 -0.033+0.075 MJ and radius of 0.808 -0.033+0.034 RJ, K2-139 b is one of the transiting wa
The central component of the complement cascade, C3, is involved in various biological functions, including opsonization of foreign bodies, clearance of waste material, activation of immune cells, and triggering of pathways controlling development. Given its broad role in immune responses, particularly in phagocytosis and the clearance of microbes, a deficiency in complement C3 in humans is often
The concept of early vascular aging (EVA) was introduced to identify adults at risk of developing premature cardiovascular disease. EVA, or the dissociation between chronologic and biologic age of large arteries, is an evolving concept. In this review, we propose that EVA in youth characterizes the early life biological and environmental risk factors that precede overt EVA. During early infancy, c
Background: Persistent circulating cell-free tumor DNA (ctDNA) detection during neoadjuvant treatment of early-breast cancer (EBC) indicates high-risk disease. Detection of ctDNA post-resection of EBC (molecular residual disease, MRD) indicates occult metastatic disease and impending disease relapse. For ctDNA to be integrated into EBC management, accessible and scalable diagnostic tools are requi
