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Robustness of distributed routing policies is studied for dynamical flow networks, with respect to adversarial disturbances that reduce the link flow capacities. A dynamical flow network is modeled as a system of ordinary differential equations derived from mass conservation laws on a directed acyclic graph with a single origin-destination pair and a constant inflow at the origin. Routing policies
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Electronic transport through a single-level quantum dot coupled to two ferromagnetic leads is studied in the sequential tunneling regime. Transport characteristics are calculated for arbitrary angle between magnetic moments of the electrodes. It is found that the diode feature in the transport characteristics is significantly suppressed for canted magnetic configurations. It is also shown that a s
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Introduction: Detection of circulating tumour cells (CTCs) in peripheral blood has an established prognostic significance in patients with metastatic breast cancer. Change in the number of detected CTCs is also an indication of response to therapy. Characterisation of CTCs could provide easily accessible treatment predictive information of present cancer cells within the patient and could reveal i
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BACKGROUND: At birth, infants' lungs are fluid-filled. For newborns to have a successful transition, this fluid must be replaced by air to enable gas exchange. Some infants are judged to have inadequate breathing at birth and are resuscitated with positive pressure ventilation (PPV). Giving prolonged (sustained) inflations at the start of PPV may help clear lung fluid and establish gas volume with
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Tuberculosis, is caused by various strains of Mycobacteria, and specifically the one by Mycobacterium tuberculosis needs effective treatment. Administration of antibiotics fails owing to multi-drug resistant capability of Mycobacterium. Traditional methods for the identification of a potential drug take time and require huge investment The present study was focused on virtual screening to identify
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In this analytical chapter we focus on human factors to shed light on what a 21st-century project might look like from within. Adopting a non-essentialist perspective to project-making, we at the same time acknowledge that the notion of human nature is blurred, dynamic, changeable, heterogeneous, and internally riven. The human condition, hence, always dictates what ontological position a project
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This study focuses on the influence of inhomogeneous corrosion on the quasi-static and cyclic properties of an Mg−Y−Nd alloy. Uniform corrosion is essential for biodegradable implant materials to avoid notching effects and premature failure. Previous studies on extruded Mg−3Y−3RE have shown a pitting tendency in Ringer’s solution at 37 °C. Tensile tests on pre-corroded samples with different corro
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Protein tyrosine phosphatases (PTPs) play an important role in cellular signaling and have been implicated in human cancers, diabetes, and obesity. Despite shared catalytic mechanisms and transition states for the chemical steps of catalysis, catalytic rates within the PTP family vary over several orders of magnitude. These rate differences have been implied to arise from differing conformational
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Climate change, migration, social injustice and loss of biodiversity are all examples of wicked problems that society is facing. The complexity and boundary-spanning nature of wicked problems require not only new competencies and skills, but also a different mindset. The responsibility of higher education is to ensure that the young people we educate are equipped with the knowledge, competencies a
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Arsenic methylating enzyme (AS3MT) genetic variations and their role in variability of As metabolism were evaluated in population of pregnant/non-pregnant women exposed to low levels of As. We have tested the associations between genotypes/haplotype of seven AS3MT SNPs and As metabolites in urine (methylation efficiency). Significant associations of individual SNPs and protective haplotype with ar
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Do we owe anything to our genetic relatives qua genetic relatives? The philosophical literature has primarily addressed this question in the context of procreation. But genetic matching databases raise the question of whether we owe anything to previously unknown genetic relatives. This article argues that influential philosophical arguments regarding moral claims to know one’s genetic origins (so
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There can be situations, for example if gas containers have been damaged in a vehicle crash, when the fire and rescue service would like to depressurize the gas containers through shooting with a civilian rifle. Modern high-pressure hydrogen containers are designed for a working pressure of 700 bars. This means that they have a very thick and strong shell made of composite material. At the same ti
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BACKGROUND: Butyric acid is produced by degradation of dietary fibre by microbiota and is crucial for maintaining a healthy colon. The physicochemical properties are important for butyric acid formation, and this study aimed to evaluate the use of malting to tailor the functional characteristics of barley dietary fibre. The effect of different steeping conditions was evaluated in laboratory-scale
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In this paper, we cast the idea of antithetic sampling, widely used in standard Monte Carlo simulation, into the framework of sequential Monte Carlo methods. We propose a version of the standard auxiliary particle filter where the particles are mutated blockwise in such a way that all particles within each block are, first, offspring of a common ancestor and, second, negatively correlated conditio
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The Swedish alternative movement’s place-making activities in the seventies have been understood as an attempt to escape the political sphere. In this thesis, I investigate the ideas and practices of societal transformation seen in rural intentional communities and, to a lesser degree, urban sites. Challenging the idea that such intentional communities were solely concerned with the creation of ‘p
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Manufacturing Renaissance, i.e. return of manufacturing to west, has been recently observed. This paper analyzes the patterns observed within each of the four main drivers behind this new phenomenon and delves more deeply into the driver that centers on the new manufacturing technologies such as Additive Manufacturing (AM) and 3D Printing. Next, this paper will make the case that the location of m
