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Capsule and PspA Cooperatively Confer Resistance of Streptococcus pneumoniae to the Human Defensin HNP-1

Streptococcus pneumoniae resists host defenses through multiple surface factors, yet their specific contribution to protection against antimicrobial peptides remains incompletely understood. We examined the role of pneumococcal surface protein A (PspA) and the polysaccharide capsule in protection against the human defensin HNP-1. PspA conferred increased resistance to HNP-1-induced killing, shown

Overcoming Immune Evasion in Staphylococcus aureus : Strategies for Rational Vaccine Design.

Staphylococcus aureus remains one of the most elusive targets in bacterial vaccinology, primarily due to its complex immune evasion strategies and the phenomenon of immune imprinting. Despite decades of research and numerous clinical trials, no vaccine has demonstrated protective efficacy in humans. This review examines the underlying reasons for these failures and proposes a rational, integrativ

Identification of a novel gene associated with group B Streptococcus persister cell formation and biofilm production

Antibiotic persistence arises when a subset of cells in an otherwise susceptible bacterial population temporarily exhibits elevated tolerance to bactericidal antibiotics. While significant progress has been made in elucidating persister mechanisms, much of this research has focused on Gram-negative bacteria, and these findings are not always applicable to Gram-positive species. This study explores

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Charlotte Tornbjer Historiska institutionen Lunds universitet Box2074 220 02 Lund CV Utbildning Fil mag i historia, Lunds universitet, 1996 HT 1989–1995 Forskarutbildning i historia, Lunds universitet 1995–2002 Fil dr i historia vid Lunds universitet 2002 med avhandlingen, Den nationella modern. Moderskap i konstruktioner av svensk nationell gemenskap under 1900-talets första hälft. Högskolepedago

https://www.ht.lu.se/media/documents/persons/CharlotteTornbjer/CV_till_forskningsdatabasen.pdf - 2026-06-06

Carl Dalhammar

Professor Contact details Email: carl [dot] dalhammar [at] iiiee [dot] lu [dot] se Phone: +46 46 222 02 43Organisation The International Institute for Industrial Environmental Economics Service point: 53 WebpageCarl Dalhammars profile in Lund University research portalOther affiliations Profile area member LU Profile Area: Human rights Affiliated professor CIRCLE Researcher Environmental Law Senio

https://www.humanrights.lu.se/carl-dalhammar - 2026-06-06

A microgel-Pickering emulsion route to colloidal molecules with temperature-tunable interaction sites

A simple Pickering emulsion route has been developed for the assembly of temperature-responsive poly(N-isopropylacrylamide) (PNIPAM) microgel particles into colloidal molecules comprising a small number of discrete microgel interaction sites on a central oil emulsion droplet. Here, the surface activity of the microgels serves to drive their assembly through adsorption to growing polydimethylsiloxa

Anisotropic mesoporous silica/microgel core-shell responsive particles

Hybrid anisotropic microgels were synthesised using mesoporous silica as core particles. By finely controlling the synthesis conditions, the latter can be obtained with different shapes such as platelets, primary particles or rods. Using the core particles as seeds for precipitation polymerisation, a crosslinked poly(N-isopropylacrylamide) (PNIPAM) microgel shell could be grown at the surface, con

A Nationwide Cohort Study of Outcome after Pediatric Appendicitis

Introduction Children with appendicitis often present with complicated disease. The aim of this study was to describe the clinical management of pediatric appendicitis, and to report how disease severity and operative modality are associated with short- and long-term risks of adverse outcome. Materials and Methods A nationwide retrospective cohort study of all Swedish children (<18 years) diagnose

Crystal-to-Crystal Transitions in Binary Mixtures of Soft Colloids

In this article, we demonstrate a method for inducing reversible crystal-to-crystal transitions in binary mixtures of soft colloidal particles. Through a controlled decrease of salinity and increasingly dominating electrostatic interactions, a single sample is shown to reversibly organize into entropic crystals, electrostatic attraction-dominated crystals, or aggregated gels, which we quantify usi

Vulnerability Analyses of Interdependent Critical Infrastructures: Case study of the Swedish National Power transmission and Railway system

Critical infrastructures provide services that are essential for the functioning of our society and extensive disruptions in these can have widespread effects. These effects are not only limited to the directly affected infrastructure but also indirectly through interdependencies to other infrastructures. By only account-ing for the direct consequences when analysing critical infrastructures, the

Preterm birth and unintentional injuries: risks to children, adolescents and young adults show no consistent pattern.

AIM: Preterm birth is associated with a number of physical and mental health issues. The aim of this study was to find out if there was also any association between individuals born preterm in Sweden between 1984 and 2006 and the risk of unintentional injuries during childhood, adolescence and young adulthood METHODS: The study followed 2,297,134 individuals, including 5.9% born preterm, from 1985

Respiratory tract deposition of inhaled wood smoke particles in healthy volunteers

Background: Respiratory tract deposition of air pollution particles is a key to their adverse health effects. This study was aimed to determine the size-resolved deposition fraction (DF) of sooty wood smoke particles in the lungs of healthy subjects. The type of wood smoke investigated is typical for household air pollution from solid fuels, which is among the largest environmental health problems

Longitudinal trends in self-reported anxiety. Effects of age and birth cohort during 25 years

Background: Anxiety has been suggested to increase among young individuals, but previous studies on longitudinal trends are inconclusive. The aim of this study was to analyze longitudinally, the changes over time of prevalence of self-reported anxiety in the Swedish population between 1980/1981 and 2004/2005, in different birth cohorts and age groups. Methods: A random sample of non-institutionali

Effect of encapsulated protein on the dynamics of lipid sponge phase: a neutron spin echo and molecular dynamics simulation study

Lipid membranes are highly mobile systems with hierarchical, time and length scale dependent, collective motions including thickness fluctuations, undulations, and topological membrane changes, which play an important role in membrane interactions. In this work we have characterised the effect of encapsulating two industrially important enzymes, β-galactosidase and aspartic protease, in lipid spon

Structure and anisotropic dynamics of stimuli responsive colloidal ellipsoids at the nearest neighbor length scale

Stimuli-responsive self-assembly of (an) isotropic colloids has resulted in a plethora of self-assembled structures with potential applications in fabricating smart materials. A lack of detailed understanding of the interplay between these self-assembled structures and the resulting dynamics has often impeded the exploitation of their full potential. Herein, we have unveiled the relationship betwe

Spatially and temporally resolved laser/optical diagnostics of combustion processes : From fundamentals to practical applications

Laser diagnostic techniques have for more than five decades been used for gaining a deepened understanding of various combustion processes. The main reason for this is the possibility of non-intrusive measurements of key combustion parameters, e.g. species concentrations, temperatures and velocities, with high spatial and temporal resolution. The present paper will describe some development of the

ArGSLab : a tool for analyzing experimental or simulated particle networks

Microscopy and particle-based simulations are both powerful techniques to study aggregated particulate matter such as colloidal gels. The data provided by these techniques often contains information on a wide array of length scales, but structural analysis methods typically focus on the local particle arrangement, even though the data also contains information about the particle network on the mes

More than protection : The function of TiO2interlayers in hematite functionalized Si photoanodes

Worldwide significant efforts are ongoing to develop devices that store solar energy as fuels. In one such approach, solar energy is absorbed by semiconductors and utilized directly by catalysts at their surfaces to split water into H2 and O2. To protect the semiconductors in these photo-electrochemical cells (PEC) from corrosion, frequently thin TiO2 interlayers are applied. Employing a well-perf