Sökresultat

Objectives: The present study aimed to identify multidimensional typologies of harmful alcohol use based on the Swedish Addiction Severity Index (ASI) assessment data on individuals aged 50 years and above.Methods: Latent class analysis examined 11 indicators from ASI data on 1747 individuals (men = 1255, women = 492) who reported they were troubled by alcohol problem at least one day in the past

As a researcher, I have spent countless hours hunting for tags. Recently, I started thinking about ways to represent not just my physical search, but also the thought process taking place alongside the visible bodily activities: remembering – for example – the style, medium, size and placement of previous tags of interest in order to better spot similar tags and their likely locations.This video i

Cancer often results from chronic inflammation, and anti-inflammatory medications are therefore potential candidates for drug repurposing for cancer therapy. H2-antihistamines such as cimetidine have long been studied for their promise as cancer medications, but H1-antihistamines have thus far not been studied widely for this purpose. We have previously shown an association with improved breast ca

Most of the common modeling approaches to premixed combustion in engineering applications are either based on the assumption of infinitely fast chemistry or the flamelet assumption with simple chemistry. The level-set flamelet library approach (FLA) has shown great potential in predicting major species and heat release, as well as intermediate and minor species, where more simple models often fail

Neoplastic disorders are characterized by recurrent somatically acquired chromosomal aberrations that alter the structure and/or expression of a large number of genes. Most “cancer genes” discovered to date in human neoplasms have been identified through isolation of genes at the breakpoints of balanced chromosomal translocations. Although functional studies of such cancer-causing genes have demon

Aim: To study (a) the covariation between patient reported experience measures (PREMs) and registered process measures of access and continuity when ranking providers in a primary care setting, and (b) whether registered process measures or PREMs provided more or less information about potential linkages between levels of access and continuity and explaining variables. Background: Access and conti

Sixteen years of hourly atmospheric pollutant data (1996-2011) in the Metropolitan Area of São Paulo (MASP), and seven years (2005-2011) of data measured in the Metropolitan Area of Rio de Janeiro (MARJ), were analyzed in order to study the extreme pollution events and their return period. In addition, the objective was to compare the air quality between the two largest Brazilian urban areas and p

The purpose of this article is (a) to review scholarly literature on entrepreneurship among Somalis in the United Kingdom and (b) through a field survey among Somali entrepreneurs in the UK assess if the prevailing image – derived from (a) – is valid or if some additional observations may alter the picture. Step (b) is accomplished through interviews with 36 Somalia-born entrepreneurs, most of the

Against the grain of the paradigmatic postcolonial analytics of the colonial state, this chapter presents a non-dichotomous comparison of two regimes within the late 18th century Danish empire, which are commonly presumed to be of essentially different kinds - namely the colonial state in Tranquebar in South East India and the metropolitan government of rural Danish society. By focusing, firstly,

The simulation of viscous, compressible flows around complex geometries or similar applications often inherit the task of solving large, stiff systems of ODEs. Domain-based implicit-explicit (IMEX) type schemes offer the possibility to apply two different schemes to different parts of the computational domain. The goal hereby is to decrease the computational cost by increasing the admissible step

The planning of facilities to improve the environment is often carried through in the form of locally based construction projects. These projects can be complex, involving a variety of issues and a number of different actors from both the public and private sectors. By drawing on previous research on project planning, an analytical model for analysing the issues connected with the planning and imp

Flexible manufacturing puts high demands on industrial automation in terms of affordable and competitive solutions and is of key importance for short-lot production typically found in small and medium sized enterprises, situations where today manual labour is extensively used despite environmental issues and harsh working conditions. Key factors in the successful introduction of new robot automati

The frame story
takes place in a dystopian Europe, possibly some kind of European Union around 2050 – in a state of conflicts and decay. The protagonists are a retired general, Piscator (cf. Fisher King) and a former journalist, Perle Vaus (cf. Perlesvaus/Perceval/Parsifal). She lost her home because of a new genderrelated law and stays homeless with others, covered by the Saxon bridge.

By "codex simulations" or codex simulaters" I intend the various hard- and software products that imitate the form of the codex and /or simulate the function of it. They can be designed with the main purpose either to transfer literary work, as with "ordinary" electronic books, or to communicate the looks of a specific original artefact, as with those simulaters used by libraries for displaying di

Introduction Proton pump inhibitors (PPIs) are used as prophylaxis, guarding against anastomotic stricture (AS) in the aftermath of reconstructed esophageal atresia (EA). The incidence of stricture formation was studied in this setting, comparing outcomes of 3- and 12-month PPI prophylactic regimens. Patients and Methods Patient characteristics (gestational age, birth weight, prevalence of chromo

This study describes the enzymatic characterization of dihydrolipoamide dehydrogenase (DLDH) from Streptococcus pneumoniae and is the first characterization of a DLDH that carries its own substrate (a lipoic acid covalently attached to a lipoyl protein domain) within its own sequence. Full-length recombinant DLDH (rDLDH) was expressed and compared with enzyme expressed in the absence of lipoic aci

Hydrogels are a hydrophilic network of polymers (usually cross-linked polysaccharides) that are natural or synthetic. Applications of hydrogels are many in the biomedical field. Because of the high water absorption (10 to 200 grams of water per gram of hydrogel), hydrogels have a high degree of flexibility similar to natural human tissue. Human cells can be incorporated into the hydrogel, which in

Diagonally implicit Runge–Kutta methods (DIRK) are evaluated and compared to standard solution procedures for finite strain crystal plasticity boundary value problems. The structure of the DIRK implementation is similar to that of a conventional implicit backward Euler scheme. It is shown that only very small modifications are required in order to transform the numerical scheme from one into the o

We have recently shown that the human Nuclear pore-associated protein (NPAP1)/C15orf2 gene encodes a nuclear pore-associated protein. This gene is one of several paternally expressed imprinted genes in the genomic region 15q11q13. Because the Prader–Willi syndrome is known to be caused by the loss of function of paternally expressed genes in 15q11q13, a phenotypic contribution of NPAP1 cannot be e