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Affärsnytta i användandet av simulering - En fallstudie av Holmen skog

Problem discussion: The process of paper production includes numerous steps from that a customer order is received to that a finished product is delivered to the customer. A desire exists at Holmen Paper to be able to ease and improve the complex operational methods through the use of computer-aided simulation. Based on the reasoning above the problem to solve in this master thesis is to resolve w

Small-scale climate variability and its ecosystem impacts in the sub-Arctic

Abstract in Undetermined To improve our knowledge of climate change and its impacts on ecosystem services, and to inform local people and governments that need assistance with the development of mitigation and adaptation strategies, climate impacts need to be understood urgently at the smaller scale. On one hand, the microclimate/topoclimate is known to be strongly decoupled from the general macro

Laccase from a Litter Degrading Fungus: Evaluation for Environmental Applications and Modification of Lignin to a Bioadhesive

Popular Abstract in Swedish The phenol oxidase “laccase” was first described towards the end of the 19th century from the wound sap of the lacquer tree Rhus vernicifera. However, its use in one of the oldest biotechnologies, i.e. the making of lacquerware in East-Asia, dates back to 5000-6000 BC. The enzyme has the widest distribution in nature among the multicopper oxidases. It catalyzes one elecLaccase, the phenol oxidizing enzyme, was first described towards the end of the 19th century from the wound sap of the lacquer tree Rhus vernicifera. The enzyme has the widest distribution in nature among the multicopper oxidases. It catalyzes single electron transfer oxidation in the presence of molecular oxygen producing water as by-product. Based on these highly desired mild oxidising conditio

Safer drug use in primary care - a pilot intervention study to identify improvement needs and make agreements for change in five Swedish primary care units

Background: There is an urgent need to improve patient safety in the area of medication treatment among the elderly. The aim of this study was to explore which improvement needs and strengths, relating to medication safety, arise from a multi-professional intervention in primary care and further to describe and follow up on the agreements for change that were established within the intervention. M

Concerns and quality of life before surgery and during the recovery period in patients with rectal cancer and an ostomy

PURPOSE: Rectal cancer is the most common reason for a person to undergo ostomy surgery. The aim of this study was to assess concerns and health-related quality of life (HRQOL) before surgery and during the first 6 months following ostomy surgery in the presence of rectal cancer.SUBJECTS AND SETTINGS: The sample comprised 57 patients at a university hospital in Gothenburg, Sweden. Their median age

Global, regional, and national levels of maternal mortality, 1990-2015 : a systematic analysis for the Global Burden of Disease Study 2015

BACKGROUND: In transitioning from the Millennium Development Goal to the Sustainable Development Goal era, it is imperative to comprehensively assess progress toward reducing maternal mortality to identify areas of success, remaining challenges, and frame policy discussions. We aimed to quantify maternal mortality throughout the world by underlying cause and age from 1990 to 2015.METHODS: We estim

Neurochemical profile of the developing mouse cortex determined by in vivo 1H NMR spectroscopy at 14.1 T and the effect of recurrent anaesthesia

The neurochemical profile of the cortex develops in a region and time specific manner, which can be distorted by psychiatric and other neurological pathologies. Pre-clinical studies often involve experimental mouse models. In this study, we determined the neurochemical profile of C57BL/6 mice in a longitudinal study design to provide a reference frame for the normal developing mouse cortex. Using

Experimental investigation on the influences of bluff-body's position on diffusion flame structures

Effects of the bluff-body's position on diffusion flame structures and flame instability characteristics were investigated experimentally. A flame regime diagram together with the corresponding flow fields were proposed to evaluate the influences caused by the alternation of bluff-body's position. The disk shape bluff-body was placed 10 mm downstream or at the same height with the annular channel

The (Im)Possibilities Of The Politics Of Solidarity: Human Rights Defenders Discourse, Humanitarian Aid Dynamics and Transmigrants Experiences In Mexico's Transit Assistance-Based Places.

Mexico has the most transited migratory corridor in the world . The complex migratory flows transiting the country—mainly Mexican, Central and South Amer- ican—have historically been perceived as economic and male . Scholars have not- ed as problematic the categorisation of the ‘labour migrant’ as being exclusive- ly voluntary. It has been demonstrated that framing agency through simplified unders

How proteins modify water dynamics

Much of biology happens at the protein-water interface, so all dynamical processes in this region are of fundamental importance. Local structural fluctuations in the hydration layer can be probed by 17O magnetic relaxation dispersion (MRD), which, at high frequencies, measures the integral of a biaxial rotational time correlation function (TCF) - the integral rotational correlation time. Numerous

Postnatal intervention for the treatment of FNAIT : a systematic review

Objective: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is associated with life-threatening bleeding. This systematic review of postnatal management of FNAIT examined transfusion of human platelet antigen (HPA) selected or unselected platelets, and/or IVIg on platelet increments, hemorrhage and mortality. Study design: MEDLINE, EMBASE and Cochrane searches were conducted until 11 May 20

Extraocular Vision in a Brittle Star Is Mediated by Chromatophore Movement in Response to Ambient Light

Almost all animals can sense light, but only those with spatial vision can “see.” Conventionally, this was restricted to animals possessing discrete visual organs (eyes), but extraocular vision could facilitate vision without eyes. Echinoderms form the focus of extraocular vision research [1–7], and the brittle star Ophiocoma wendtii, which exhibits light-responsive color change and shelter seekin

Climate innovations in the plastic industry: Prospects for decarbonisation

Plastics are efficient materials for many purposes, e.g. packaging and construction, but are also associated with significant problems. These span from littering in forests and oceans, toxicity of additives, to the fundamental dependence on fossil resource for the production of the plastic material. This report aims to give an overview of the challenges for decarbonisation of plastics, i.e. moving

Components of local adaptation and divergence in pollination efficacy in a coevolving species interaction

Selection leading to adaptation to interactions may generate rapid evolutionary feedbacks and drive diversification of species interactions. The challenge is to understand how the many traits of interacting species combine to shape local adaptation in ways directly or indirectly resulting in diversification. We used the well-studied interactions between Lithophragma plants (Saxifragaceae) and Grey

Age and sex differences in cause-specific excess mortality and years of life lost associated with COVID-19 infection in the Swedish population

Background: Estimating excess mortality and years of life lost (YLL) attributed to coronavirus disease 19 (COVID-19) infection provides a comprehensive picture of the mortality burden on society. We aimed to estimate the impact of the COVID-19 pandemic on age- and sex-specific excess mortality and YLL in Sweden during the first 17 months of the pandemic. Methods: In this population-based observati

Association between the rs1544410 polymorphism in the vitamin D receptor (VDR) gene and insulin secretion after gestational diabetes mellitus

BACKGROUND AND AIMS: Genetic variants involved in vitamin D metabolism have been associated with diabetes and related syndromes/diseases. We wanted to investigate possible associations of polymorphisms in genes involved in vitamin D metabolism with indices of insulin resistance and insulin secretion, and also with development of diabetes after gestational diabetes mellitus (GDM).MATERIALS AND METH

Avocado production and local trade in the southern highlands of Tanzania : A case of an emerging trade commodity from horticulture

Avocado crop in Tanzania is sparingly investigated regardless of being an important fruit commodity. This study was undertaken to explore the yield and the value chain of this crop in the country. Data were collected mainly by face-to-face interviews with 275 avocado farmers, 231 avocado traders and 16 key informants. Descriptive statistics, Chi-square test and one-way analysis of variance were us

Serologic markers of Chlamydia trachomatis and other sexually transmitted infections and subsequent ovarian cancer risk : Results from the EPIC cohort

A substantial proportion of epithelial ovarian cancer (EOC) arises in the fallopian tube and other epithelia of the upper genital tract; these epithelia may incur damage and neoplastic transformation after sexually transmitted infections (STI) and pelvic inflammatory disease. We investigated the hypothesis that past STI infection, particularly Chlamydia trachomatis, is associated with higher EOC r

Integrating spatial gene expression and breast tumour morphology via deep learning

Spatial transcriptomics allows for the measurement of RNA abundance at a high spatial resolution, making it possible to systematically link the morphology of cellular neighbourhoods and spatially localized gene expression. Here, we report the development of a deep learning algorithm for the prediction of local gene expression from haematoxylin-and-eosin-stained histopathology images using a new da

RECOMIA—a cloud-based platform for artificial intelligence research in nuclear medicine and radiology

Background: Artificial intelligence (AI) is about to transform medical imaging. The Research Consortium for Medical Image Analysis (RECOMIA), a not-for-profit organisation, has developed an online platform to facilitate collaboration between medical researchers and AI researchers. The aim is to minimise the time and effort researchers need to spend on technical aspects, such as transfer, display,