Sökresultat

Popular Abstract in Swedish Vår hud och våra slemhinnor är ständigt koloniserade med bakterier som lever i fredligt samspel med vår organism. Dessa bakterier tillhör vår normalflora och kan indelas i kommensaler respektive opportunistiska bakterier. Kommensalerna gagnar värden på olika sätt och orsakar inte sjukdom, till skillnad från opportunisterna som under vissa betingelser kan orsaka infektioAbstractBacteria in most environments encase themselves in a hydrated matrix of polysaccharide and protein, forming organized communities called biofilms. In the biofilm bacteria are protected against hostile environments. Biofilms are important clinically because of their persistence despite host defence and their recalcitrance to antimicrobials. This thesis presents three main findings: (i) biof

This work investigates the prospective impacts of climate change on wind-driven rain (WDR) and walls through simulating the hygrothermal performance of rain screen of common vertical wall constructions for the climatic conditions of Gothenburg in Sweden. While a substantial amount of work has been done on the impact of climate change on the thermal performance of buildings, this paper studies its

Cartilage is of vital importance for the function of joints. It is characterized by a prominent extracellular matrix (ECM) that is produced and maintained by relatively few cells of one type, the chondrocyte. The cartilage ECM consists of collagen fibrillar networks, proteoglycan aggregates, and a number of other molecules united in numerous interactions. This work focused at identifying catabolic

Föreliggande avhandling argumenterar för värdet av ett långsiktigt planetärt perspektiv i politiken. Vi har blivit vana att tänka på de risker som moderniteten genererar utifrån ett vidgat tidsligt och rumsligt perspektiv (till exempel utgör år 2100 en återkommande referenspunkt för forskningen kring globala klimatförändringar). På samma sätt bör vi fråga oss vilka politiska möjligheter som mänsklThis thesis propounds a techno-environmentalist position. Seeking to combine the need for natural restoration with human development, the thesis explores to what extent more radical forms of ecological modernization can offer a basis for political compromise and open new paths to global long-term sustainability. Based on three published articles, the thesis engages with existing literature on (a)

BACKGROUND: A horizontal gene transfer has brought an active nuclear gene, PgiC2, from a polyploid Poa species (P. palustris or a close relative) into the common grass sheep's fescue (Festuca ovina). The donor and the receptor species are strictly reproductively separated, and PgiC2 occurs in a polymorphic state within F. ovina. The active gene copy is normally closely linked to a very similar pse

Hybridization between populations or species can have pronounced fitness consequences. Yet little is known about how hybridization affects gene regulation. Three main models have been put forward to explain gene expression patterns in hybrids: additive, dominance or parental effects. Here we use high throughput RNA-sequencing to examine the extent to which hybrid gene expression follows prediction

The use of brominated flame retardants (BFRs) such as polybrominated diphenyl ethers (PBDEs) in aircraft is the result of high fire safety demands. Personnel working in or with aircraft might therefore be exposed to several BFRs. Previous studies have reported PBDE exposure in flight attendants and in passengers. One other group that may be subjected to significant BFR exposure via inhalation, are

Factor I (FI) is a serine protease that inhibits all complement pathways by degrading activated complement components C3b and C4b. FI functions only in the presence of several cofactors such as factor H, C4b-binding protein, complement receptor 1 and membrane cofactor protein. FI is composed of two chains linked by a disulphide bridge; the light chain comprises only the serine protease (SP) domain

Abstract The endangered minnow Iberochondrostoma almacai is an endemic Iberian cyprinid with a restricted and fragmented distribution. Here, we describe the genetic structure of the species and infer its demographic history from six nuclear-encoded microsatellite loci and mitochondrial cytochrome b sequences. Genetic diversity was low (microsatellite He<0.45; mtDNA π<0.0015), and both markers reso

This study evaluated a technique to allow the long-term monitoring of individual fishes of known sex in the wild using sex confirmation in close proximity to the reproductive period combined with individual tagging. Hundreds of partially migratory roach Rutilus rutilus were tagged with passive integrated transponders (PIT) following sex determination in spring and various performance measures were

Most of the traditional technicolor-based models are known to be in a strong tension with the electroweak precision tests. We show that this serious issue is naturally cured in strongly coupled sectors with chiral-symmetric vectorlike gauge interactions in the framework of the gauged linear sigma model. We discuss possible phenomenological implications of such a nonstandard chiral-symmetric techni

The bleeding patterns of severe von Willebrand's disease (VWD) adversely affect quality of life, and may be life threatening. There is a presumed role for prophylaxis with VWF-containing concentrates, but data are scarce. The von Willebrand Disease Prophylaxis Network (VWD PN) was formed to investigate the role of prophylaxis in clinically severe VWD that is not responsive to other treatment(s). U

Nocturnal passerine migrants could substantially reduce the amount of energy spent per distance covered if they fly with tailwind assistance and thus achieve ground speeds that exceed their airspeeds (the birds' speed in relation to the surrounding air). We analysed tracking radar data from two study sites in southern and northern Scandinavia and show that nocturnally migrating passerines, during

Background More than 1100 mutations that cause hemophilia B (HB) have been identified. At the same time, specific F9 mutations are present at high frequencies in certain populations, which raise questions about the origin of HB mutations. ObjectivesTo describe the mutation spectrum of all HB families in Sweden and investigate if mutations appearing in several families are due to independent recurr

Characterization of the count-rate performance of scintillation cameras should include not only the specification of count losses. At high count rates, there is also an image distortion due to the mispositioning of pile-up events. In this paper a simple and clinically relevant procedure to quantify this distortion is presented. The images of a square uniform technetium-99m phantom at high and low

A novel volatile microemulsion formed by the catanionic surfactant hexadecyltrimethylammonium octylsulfonate (TA(16)So(8)), heptane and water has been explored as a template for producing nanoparticles of hydrophobic organic materials. Butylated hydroxytoluene (BHT) was employed as the model hydrophobic substance. First, the oil-in-water microemulsion was formed, containing TA16So8 as the single e

Many issues in computational vision can be understood from the interplay between camera geometry and the structure of images and objects. Typically, the image structure is available and the goal is to reconstruct object structure and camera geometry. This is often difficult due to the complex interdependence between these three entities. The theme of this thesis is to use invariants to solve these

Intestinal spirochetes (Brachyspira spp.) are causative agents of intestinal disorders in animals and humans. Phylogenetic analysis of cloned 16S rRNA genes from biopsies of the intestinal mucosa of the colon from two Swedish 60-years old adults without clinical symptoms revealed the presence of intestinal spirochetes. Seventeen clones from two individuals and 11 reference strains were analyzed an

The effect of photodynamic therapy on tape-stripped normal human skin was explored ultrastructurally. Back skin areas of 3 healthy Caucasian volunteers, 2 men and 1 woman, were tape-stripped 10 consecutive times followed by topical treatment with 5-aminolevulinic acid (20%, w/w) for 4 hours under occlusion (Tegaderm(R)). Then the areas were irradiated for 30 minutes with Waldman PDT 1200 lamp (570