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Socialt entreprenörskap – informations- och kommunikationsteknologi för lokal handlingsgemenskap

The theoretical findings of the thesis is composed of three parts, it consists of (i) a framework for social entrepreneurship, (ii) some pitfalls and success factors and (iii) a perspicuous design guide. These findings was a result of field research during a long time – more than 5 years, 2000-2005 – and the scientific purpose was to give a broad description and understanding of the research probl

Med Lenin på byrån - normer kring klass, genus och sexualitet i den svenska kommunistiska rörelsen 1921-1939

The thesis Med Lenin på byrån (With Lenin on the drawer) studies magazines produced by the Swedish communist movement during the inter-war years and has two aims; firstly to determine if (and how) class-norms were constructed through descriptions of gender and sexuality, and secondly if (and how) norms regarding gender and sexuality were constructed through descriptions of class. One of the underl

Defining a free market: drivers of unsustainability as illustrated with an example of shrimp farming in the mangrove forest in South East Asia

We apply causal loop diagrams (CLD) to picture how complex societal scenarios can be understood in terms of interdependent drivers and mechanisms between actors from the public and private sectors respectively. And we show how un-sustainable scenarios can be understood in terms of insufficient balancing feed-back in the system. We apply the methodology to picture such imbalances as funda- mental d

In-kind transfers of maize, commercialization and household consumption in Kenya

This article discusses in kind food transfers and whether such transfers should be interpreted as a sign of the failure of grain markets to meet the food demands of the poor. The paper elucidates on aspects of both consumption and in kind transfers of maize against a backdrop of poorly functioning markets. The paper adds to the theoretical understanding of household based linkages and provides a d

Influence of weather variables on methane and carbon dioxide flux from a shallow pond

Freshwaters are important sources of the greenhouse gases methane (CH4) and carbon dioxide (CO2) to the atmosphere. Knowledge about temporal variability in these fluxes is very limited, yet critical for proper study design and evaluating flux data. Further, to understand the reasons for the variability and allow predictive modeling, the temporal variability has to be related to relevant environmen

Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility

Genetic susceptibility accounts for similar to 35% of all colorectal cancer (CRC). Ten common low-risk variants contributing to CRC risk have been identified through genome-wide association studies (GWASs). In our GWAS, 610 664 genotyped single-nucleotide polymorphisms (SNPs) passed the quality control filtering in 371 German familial CRC patients and 1263 controls, and replication studies were co

Gold standard program for heavy smokers in a real-life setting.

Background: High-intensity smoking cessation programs generally lead to more continuous abstinence, however, lower rates of success have been reported among heavy smokers. The aim was to evaluate continuous abstinence among heavy smokers during the intensive 6-week Gold Standard Program (GSP) and to identify modifiable factors associated with continuous abstinence. Methods: In this nationwide clin

Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time

p53 is involved in stress response, metabolism and cardiovascular functioning. The C-allele of rs1042522 in the gene encoding for p53 is associated with longevity and cancer. In this study, we aimed to investigate the association of rs1042522 with changes in blood pressure, BMI and waist circumference using a longitudinal approach. Rs1042522 was analyzed in two longitudinal studies; the Doetinchem

Improving a plot-scale methane emission model and its performance at a northeastern Siberian tundra site

In order to better address the feedbacks between climate and wetland methane (CH4) emissions, we tested several mechanistic improvements to the wetland CH4 emission model Peatland-VU with a longer Arctic data set than any other model: (1) inclusion of an improved hydrological module, (2) incorporation of a gross primary productivity (GPP) module, and (3) a more realistic soil-freezing scheme. A lo

Comparison of the vasodilator responses of isolated human and rat middle meningeal arteries to migraine related compounds

Migraine attacks occur spontaneously in those who suffer from the condition, but migraine-like attacks can also be induced artificially by a number of substances. Previously published evidence makes the meninges a likely source of migraine related pain. This article investigates the effect of several vasodilators on meningeal arteries in order to find a connection between the effect of a substance

Best practices interventions to improve quality of care of people with dementia living at home.

Objective: To identify effective interventions which improve quality of care for people with dementia (PwD) living at home. METHODS: MEDLINE-(via PubMed), CINAHL, PsycINFO and ISI Web of Science databases were searched. Inclusion criteria: (1) randomized controlled trials; (2) published in English-language, peer-reviewed journals between 1990 and 2012; (3) evaluated strategies to improve quality

Non-ecological speciation, niche conservatism and thermal adaptation: how are they connected?

During the last decade, the ecological theory of adaptive radiation, and its corollary "ecological speciation", has been a major research theme in evolutionary biology. Briefly, this theory states that speciation is mainly or largely the result of divergent selection, arising from niche differences between populations or incipient species. Reproductive isolation evolves either as a result of direc

The 21st century landscape of adult fractures - Cohort study of a complete adult regional population.

Recent reports on adult fracture epidemiology have focused mainly on the hip in elderly where increasing rates lately have changed to a decline. New reports of the preponderance of non-hip fractures in expenditure call for a wider scope. We therefore examined current overall and site-specific fracture epidemiology in adults. We ascertained all fractures diagnosed in in- and out-patient care in all

Random mutagenesis of amelogenin for engineering protein nanoparticles.

Nanoparticles made from recombinant proteins offer excellent potential for several nanotechnological applications. However, only a very limited number of proteins are currently being used for such purposes due to limited availability and stability. Therefore, we have investigated the enamel matrix protein amelogenin as a new alternative protein for use as recombinant nanoparticles. Amelogenin is a

Left atrioventricular plane displacement determined by echocardiography: a clinically useful, independent predictor of mortality in patients with stable coronary artery disease

Background. Echocardiographically determined left atrioventricular plane displacement (AVPD) is strongly related to prognosis in patients with chronic heart failure and in postmyocardial infarction patients. We aimed at exploring whether AVPD, unlike ejection fraction, is related to mortality in patients with stable coronary artery disease (CAD). Methods and results. Atrioventricular plane displac

Reduced leptin concentrations in subjects with type 2 diabetes mellitus in Sudan.

Differences have been observed in the relationship between leptin and metabolic perturbations in glucose homeostasis. Because no information is available from indigenous African populations with diabetes, the purpose of this study was to investigate the possible associations between leptin and different clinical and biochemical characteristics of a large group of subjects with type 2 diabetes mell

Phase behavior of polyion-surfactant ion complex salts: Effects of surfactant chain length and polyion length

The aqueous phase behavior of a series of complex salts, containing cationic surfactants with polymeric counterions, has been investigated by visual inspection and small-angle X-ray scattering (SAXS). The salts were alkyltrimethylammonium polyacrylates, C(x)TAPA(y), based on all combinations of five surfactant chain lengths (C-6, C-8, C-10, C-12, and C-16) and two lengths of the polyacrylate chain

The Children’s Revised Impact of Event Scale (CRIES): Validity as a screening instrument for PTSD.

The Children’s Revised Impact of Event Scale (CRIES) is a brief child-friendly measure designed to screen children at risk for Posttraumatic Stress Disorder (PTSD). It has good face and construct validity, a stable factor structure, correlates well with other indices of distress, and has been used to screen very large samples of at-risk-children following a wide range of traumatic events. However,

Archaeal abundance across a pH gradient in an arable soil and its relationship with bacterial and fungal growth rates.

Soil pH is one of the most influential factors for the composition of bacterial and fungal communities, but the influence of soil pH on the distribution and composition of soil archaeal communities has yet to be systematically addressed. The primary aim of this study was to determine how total archaeal abundance (qPCR based estimates of 16S rRNA gene copy numbers) is related to soil pH across a pH