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Effects of Age and Multiple Vaginal Births on Lower Urinary Tract Structure and Function in Nonhuman Primates

Purpose: The relative roles of urinary sphincter damage, aging, and childbirth in stress urinary incontinence (SUI), have not been established. This study was performed to elucidate the roles of these factors. Methods: The study included: (1) 8 female cynomolgus monkeys (17–19 years of age and 7–8 vaginal births each); (2) six 5-year-old nulliparous monkeys with surgically created chronic urinary

Global distribution of DNA hydroxymethylation and DNA methylation in chronic lymphocytic leukemia

Background: Chronic lymphocytic leukemia (CLL) has been a good model system to understand the functional role of 5-methylcytosine (5-mC) in cancer progression. More recently, an oxidized form of 5-mC, 5-hydroxymethylcytosine (5-hmC) has gained lot of attention as a regulatory epigenetic modification with prognostic and diagnostic implications for several cancers. However, there is no global study

Antimicrobial peptide therapy for tuberculosis infections

Tuberculosis is a communicable disease that persists as a second leading cause for death, by an infectious agent. Several reasons contribute to this issue to this, of which an upsurge in antibiotic resistance is of top concern. Resistance patterns in the form of mono or multidrug resistance was reported to most clinical therapies at our disposal. This thesis aims to address this issue by studying

Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

Background Quinquennial overviews (1985-2000) of the randomised trials in early breast cancer have assessed the 5-year and 10-year effects of various systemic adjuvant therapies on breast cancer recurrence and survival. Here, we report the 10-year and 15-year effects. Methods Collaborative meta-analyses were undertaken of 194 unconfounded randomised trials of adjuvant chemotherapy or hormonal ther

Respiratory and allergic outcomes among 5-year-old children exposed to pesticides

Background: Little is known about the effects of pesticides on children's respiratory and allergic outcomes.We evaluated associations of prenatal and current pesticide exposures with respiratory and allergic outcomes in children from the Infants' Environmental Health Study in Costa Rica.Methods: Among 5-year-old children (n=303), we measured prenatal and current specific gravity-corrected urinary

Quantitative relationships of perfluoroalkyl acids in drinking water associated with serum concentrations above background in adults living near contamination hotspots in Sweden

Contaminated drinking water (DW) is a major source of exposure to per- and polyfluoroalkyl substances (PFAS) at locations around PFAS production/use facilities and military airports. This study aimed to investigate quantitative relationships between concentrations in DW and serum of nine perfluoroalkyl acids (PFAAs) in Swedish adult populations living near contamination hotspots. Short-chained (PF

Characterization of quantitative trait loci for growth and meat quality in a cross between commercial breeds of swine

A three-generation resource family was created by crossing two Berkshire grandsires with nine Yorkshire granddams to identify QTL affecting growth, body composition, and meat quality. A total of 512 F2 offspring were evaluated for 11 traits related to growth and body composition and 28 traits related to meat quality. All animals were initially genotyped for 125 markers across the genome. The objec

Pharyngotonsillitis in primary health care. Aetiology and clinical findings.

Faryngotonsillit, eller halsfluss, är en vanlig orsak till att patienter söker primär-vård och är även en vanlig orsak till antibiotikaförskrivning. Bakterien Grupp A-streptokocker (GAS) har sedan länge varit den viktigaste mikroorganismen vid halsfluss, inte minst på grund av dess koppling till följdsjukdomar som exempelvis reumatisk hjärtsjukdom, men det finns många andra bakterier och virus somPharyngotonsillitis, or acute sore throat, is a common reason for attending primary health care and a common reason for antibiotic prescription. Group A Streptococcus (GAS) has long been considered the most important pathogen in pharyngotonsillitis, but a wide array of other bacteria and viruses have also been associated with this condition. However, few studies have used modern approaches for aet

Sunrise of an Industry : Solar Energy under Financial and Industrial Capitalism in the U.S. and Japan, 1973 - 2005

The thesis addresses the question of how to mitigate climate change by studying the emergence of solar photovoltaic energy as an example of a low carbon industry. By outlining the social conditions behind the growth of that industry, I aim to further the understanding of low carbon industrial development in general. The dissertation is a historical comparative study of solar photovoltaic developme

Neurons against Noise : Neural adaptations for dim light vision in hawkmoths

Alla djur uppfattar världen med sina sinnen, vilka ger information till beslut och rörelser. Tyvärr har sinnena begränsningar och när de upphör att ge pålitlig information kommer djurets överlevnad att hotas. Synsinnet till exempel utmanas dagligen, eftersom dess signalstyrka minskar när mörkret faller och ökar igen när solen går upp. I denna avhandling undersökte jag synsystemets anpassningar hosAll animals perceive the world through their senses, which form the basis for their decisions and motor actions. However, when these all-important senses reach their limit and cease to provide reliable information, the animal’s survival is threatened. Among the senses, vision is brought to its limits on a daily basis, because its signal strength is diminished as night falls, and increases again as

Review and Benchmarking of Alternative Fuels in Conventional and Advanced Engine Concepts with Emphasis on Efficiency, CO2, and Regulated Emissions

Alternative fuels have been proposed as a means for future energy-secure and environmentally sustainable transportation. This review and benchmarking show that several of the alternative fuels (e.g. methanol, ethanol, higher alcohols, RME, HVO, DME, and biogas/CNG) work well with several different engine concepts such as conventional SI, DICI, and dual fuel, and with the emerging concepts HCCI, RC

Relation between the structure and spectroscopic properties of blue copper proteins

The electronic spectra of three rhombic type 1 blue copper proteins, nitrite reductase, pseudoazurin, and cucumber basic protein, have been studied by ab initio multiconfigurational second-order perturbation theory (the CASPT2 method). The six lowest excitations have been calculated and assigned with an error of less than 1800 cm-1. The singly occupied orbital in the ground-state forms a strongly

Quality of life and hernia development 5 years after open abdomen treatment with vacuum-assisted wound closure and mesh-mediated fascial traction

Purpose: To report incisional hernia (IH) incidence, abdominal wall (AW) discomfort and quality of life (QoL) 5 years after open abdomen treatment with vacuum-assisted wound closure and mesh-mediated fascial traction (VAWCM). Methods: Five-year follow-up of patients included in a prospective study 2006–2009. The protocol included physical examination, patient interview, chart review, questionnaire

İnsan Hakları Araştırmaları Hibe Programı (İHAHP) - The Raoul Wallenberg Institute of Human Rights a

İnsan Hakları Araştırmaları Hibe Programı (İHAHP) - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Eval

https://rwi.lu.se/insan-haklari-arastirmalari-hibe-programi-ihahp/ - 2026-06-05

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A 1. Identifikation och grundläggande uppgifter 1. Kurskod MHIA11 2. Kursens namn Mediehistoria: Grundkurs 3. Nivå och kod för fördjupning i förhållande till examensfordringarna G1N, Grundnivå har endast gymnasiala förkunskapskrav 4. Högskolepoäng 30 5. Beslutsuppgifter Fastställd 2013-05-23 i enlighet med Arbets- och delegationsordning för Humanistiska och teologiska fakulteterna. 6. Ändringsuppg

https://www.historiska.lu.se/media/utbildning/dokument/kursplaner/MHIA01.pdf - 2026-06-05

Evidence for archaeal methanogenesis within veins at the onshore serpentinite-hosted Chimaera seeps, Turkey

Serpentinite-hosted ecosystems are potential sites where life may first have evolved on Earth. Serpentinization reactions produce strongly reducing and highly alkaline fluids that are typified by high concentrations of molecular hydrogen (H2) and methane (CH4), which can be used as an energy source by chemosynthetic life. Low-temperature serpentinization at slow-spreading mid-ocean ridges provides

Lateralization of sucrose responsiveness and non-associative learning in honeybees

Lateralization is a fundamental property of the human brain that affects perceptual, motor, and cognitive processes. It is now acknowledged that left-right laterality is widespread across vertebrates and even some invertebrates such as fruit flies and bees. Honeybees, which learn to associate an odorant (the conditioned stimulus, CS) with sucrose solution (the unconditioned stimulus, US), recall t

Possible VAT implications due to voluntary and involuntary transfer pricing adjustments in the EU

Mervärdesskatt och Transfer Pricing är två av de stora områdena inom internationell skatterätt, då det förra är en indirekt skatt och baseras på det subjektiva priset och det senare området tillhör direkt beskattning och använder ett objektivt, fiktivt pris för beräkning kan de vid första anblick sakna anknytning. Det finns dock en risk att justeringar av det pris som använts för Transfer Pricing-Value added tax and Transfer Pricing are two of the major areas of international tax law, as the former one uses a subjective price for the calculation of taxation and the latter one uses an objective price the two regimes seemingly lack interaction. There is however a possibility that an adjustment of the price used for Transfer Pricing purposes might have an effect on the VAT due. VAT is a har

Immunological effects of alpha-lactalbumin-enriched low-protein infant formula : A randomized controlled trial

Objectives: Breast-fed (BF) have lower risk of infections during infancy compared to those formula-fed (FF). A higher content of alpha-lactalbumin (α-lac) in breast milk, which may promote a more favorable gut microbiota, could be one reason. In this study, we evaluated whether increased concentration of α-lac in low-protein infant formula affects the immune response and the incidence of infection

Rullande bärighetsmätning i vägprojekt

Syftet med detta arbete är att undersöka om rullande bärighetsmätningar RWD är ett alternativ till fallviktsmätningar FWD i arbetet kring vägbärighet i vägprojekt. Bärighet beskrivs av Trafikverket som ” Den högsta last, enstaka eller ackumulerad, som kan accepteras med hänsyn till uppkomst av sprickor eller deformationer”. Det vill säga hur tunga fordon en väg eller en bro kan belastas med sThe purpose of this project is to investigate if RWD is an alternative to FWD in analysing road bearing capacity in road projects. According to the Swedish Transport Administration (Trafikverket), the definition of bearing capacity is described as “the maximum load whether single or cumulative, that can be accepted without causing cracking or deformation”. In other words, it refers to how muc